Best Natural Mushrooms Supplements of 2025

Elisa Drew Avatar
Elisa Drew
Last Updated: Jan 9, 2025

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Natural mushroom supplements are a popular choice for those looking to boost their overall health and wellbeing. These supplements are made from a variety of different mushroom species, each with its own unique set of benefits. Some of the most popular mushroom supplements include reishi, cordyceps, and lion's mane. Reishi mushrooms are known for their immune-boosting properties, while cordyceps are often used to improve athletic performance and endurance. Lion's mane mushrooms are believed to support cognitive function and may even have neuroprotective effects. Overall, natural mushroom supplements offer a safe and effective way to support your health and wellness goals.

At a Glance: Our Top Picks

Kaya Naturals Mushroom Complex Supplement Cover #TOP 1
Kaya Naturals Mushroom Complex Supplement
ftb score rating icon 9.8
Genius Mushroom Supplement Cover #TOP 2
Genius Mushroom Supplement
ftb score rating icon 9.7
Dr. Emil Nutrition Lions Mane Mushroom Supplement Cover #TOP 3
Dr. Emil Nutrition Lions Mane Mushroom Supplement
ftb score rating icon 9.5

Top 10 Natural Mushrooms Supplements

#TOP 1

Kaya Naturals Mushroom Complex Supplement

KNMUS180
Kaya Naturals Mushroom Complex Supplement Cover
Kaya Naturals Premium Mushroom Complex Potent | Organic Mushroom Supplement| Mushroom Complex Capsules 1995mg Per Serving - Aids Mental Clarity Supports Immune System, Wellness & Vitality | 180 Count

Kaya Naturals Premium Mushroom Complex Potent Supplement is a blend of 10 organic and potent mushrooms that helps in boosting the user's immune system, energy levels, brain health, and cognition. One of the key benefits of using this mushroom supplement is its antioxidant properties that help in fighting off free-radicals and combat oxidative stress. The supplement is made in the USA with all-natural, non-GMO, and gluten-free ingredients that are 3rd party lab-tested to ensure the highest quality.

What We Like
Contains 10 of nature's most potent and beneficial mushrooms
Boosts energy levels and vitality
Supports healthy immune system and brain health
All-natural, non-GMO, and gluten-free ingredients
3rd party lab-tested to ensure highest quality

Genius Mushroom Supplement

GEN1006/100/101
Cream
Genius Mushroom Supplement Cover
Genius Mushroom Supplement - Lions Mane, Cordyceps, Reishi - Brain Nootropic for Energy, Focus, Overall Wellness, & Immune Support - 90 Capsules

Genius Mushroom Supplement is a unique blend of three of the most researched mycological species on the planet. This organic formula enhances mental clarity, immune function, natural energy, and more. It is a caffeine-free energy supplement that elevates energy levels naturally via ATP production with Cordyceps Sinensis. The Lions Mane provides a safe alternative to highly questionable nootropics and smart drugs hitting the market nowadays. This species is a proven brain booster, great for work and studying. The Reishi mushroom extract elevates immune support to another level. It has been used for centuries as an immune booster to stay healthy and avoid the common cold. Reishi has also been shown to improve mood and potentially act as a detoxifying liver cleanse. There isn't another formula on the market that delivers like this.

What We Like
Boosts immune system
Enhances brain function
Natural energy support
#TOP 3

Dr. Emil Nutrition Lions Mane Mushroom Supplement

Dr. Emil Nutrition Lions Mane Mushroom Supplement Cover
DR. EMIL NUTRITION 9000mg Organic Lions Mane Supplement Capsules with Chaga, Reishi & Maitake - Natural Mushroom Blend for Wellness Support

The Dr. Emil Lions Mane Supplement offers natural support for your cognitive health and mental clarity, helping you maintain focus throughout the day. Each serving delivers a potent dose of 900mg of Lion's Mane extract, equivalent to 9000mg of mushroom powder, ensuring you receive maximum benefits. Additionally, this supplement features a blend of other beneficial mushrooms like Chaga, Maitake, and Reishi, each contributing to your overall wellness. Sourced from high-quality, USA-grown mushrooms and processed using advanced methods, these capsules are designed to retain essential nutrients for optimal health support.

What We Like
Cognitive function support
High dosage of Lion's Mane
Includes additional beneficial mushrooms
Quality USA-grown ingredients

Lions Mane Mushroom Supplement with 20 Types of Mushroom Extract

Mushroom Supplement 20in1
Natural
Lions Mane Mushroom Supplement with 20 Types of Mushroom Extract Cover
Clean Nutraceuticals Lions Mane 20in1 Mushroom Supplement with Turkey Tail Reishi Cordyceps Chaga Maitake Meshima Poria Cocos Shiitake Oyster Porcini Enoki - Pack

Clean Nutra's Lions Mane Mushroom Supplement is an all-in-one solution that contains 20 different types of mushroom extract. It includes 5 full-dose mushroom supplements in one, containing a full lions mane powder, turkey tail mushroom powder, reishi mushroom extract, chaga powder, and cordyceps capsules in a convenient 2 capsule dosage. The ShroomZoom Blend also includes 15 additional powerhouse mushrooms such as Maitake, Meshima, Poria Cocos, Shiitake, Tremella, Oyster, Agaricus, Porcini, Enoki and more. It's a powerful cognitive support supplement and nootropic booster, made with vetted and trusted ingredients in the USA.

What We Like
Contains 20 different types of mushroom extract
Powerful cognitive support supplement and nootropic booster
Vetted and trusted ingredients made in the USA
#TOP 5

Lions Mane Mushroom Gummies - Mushroom Complex Immune Defense

DNIUTY
Mixed Fruits
Lions Mane Mushroom Gummies - Mushroom Complex Immune Defense Cover
Ashwagandha and Lions Mane Mushroom Supplement Gummies - Organic - Reishi, Cordyceps, Turkey Tail, Maitake, Shitake, Chaga - Immune Defense, Boosts Cognitive Performance, Vegan, Low Carb

The Lions Mane Mushroom Supplement Gummies are a premium mushroom vitamin gummy that act as an effective immune defense booster. This advanced mushroom blend includes Chaga, Maitake, Turkey Tail, Shitake, Reishi, and Cordyceps, as well as the added benefits of lion's mane and ashwagandha. These mushrooms have been traditionally used to support overall health and wellness, mental clarity, and focus. It is a 100% vegan-friendly formula, non-GMO, gluten-free, and contains organic ingredients which ensures purity, safety, and effectiveness. The natural berry flavor makes it a delicious daily supplement.

What We Like
Premium and advanced mushroom blend
Effective immune defense booster
100% vegan-friendly formula
Non-GMO and gluten-free
Delicious natural berry flavor
#TOP 6

Mushroom Supplement for Immune System & Brain Performance

Mushroom Supplement for Immune System & Brain Performance Cover
ACEWORKZ 10 Mushroom Complex Supplement - Lions Mane, Reishi and Cordyceps & More - Nootropic for Brain Health, Memory & Focus - Immunity & Energy (90 Capsules)

ACEWORKZ Mushroom Supplement features 10 types of mushrooms that optimize your Mind, Body, and Spirit. The formula is designed to support clarity, focus, memory recall, and help reduce brain fog. The 10-in-1 formula balances nature's best mushrooms in two capsules, delivering the optimal potency and purest ingredients per serving. It also strengthens and supports your immune system, fuel energy and relieves stress. The mushrooms naturally elevate energy levels leading to more productivity and athletic endurance. The blend is refined to support stress with the mushrooms natural calming properties. The product comes with a 60-day 100% satisfaction guarantee.

What We Like
Improved focus
Natural energy boost
Immune booster

Etta Vita Organic Mushrooms Capsules

Etta Vita Organic Mushrooms Capsules Cover
USDA Organic Lions Mane Supplement Capsules with Ashwagandha, Chaga, Reishi, Cordyceps, Turkey Tail (18,600mg/serv) 10x Adaptogenic Mushroom Complex as Focus Supplement - Energy, Immunity & Nootropic

Etta Vita Mushrooms Supplement is a USDA Organic blend of 10 mushrooms like Lion's Mane, Reishi, and Cordyceps. This supplement, made in the USA, offers a potent mix of nutrients and health-promoting compounds. With a 10x concentration, it supports focus, energy, immunity, and nootropic benefits. The inclusion of adaptogenic mushrooms helps your body adapt to stress, promoting overall well-being. Additionally, the product provides enhanced immune support, fortifying your natural defenses. Trust the USDA organic badge for superior quality and efficacy.

What We Like
USDA Organic
10-in-1 Mushroom Blend
Enhanced Immune Support
#TOP 8

HERBIFY Lions Mane Mushroom Supplement

4 Fl Oz (Pack of 1)
HERBIFY Lions Mane Mushroom Supplement Cover
Lions Mane Supplement - Daily Mushroom Supplement for Memory, Focus & Clarity - Brain Booster - Lions Mane Tincture for Natural Immune Support - Vegan, Organic - 4 Fl oz

Boost your brain power and immune system with HERBIFY Lions Mane Mushroom Supplement. Made from pure and organic wild ingredients, this lion's mane tincture comes in an easy-to-use glass dropper that enhances your daily life. This supplement is loaded with antioxidants that promote a strong immune response versus stressors. Taking Lions Mane in liquid form is more effective than taking powder, making it a superior quality product. Made in the USA with strict quality control, this supplement is suitable for adults who need immune support. Plus, satisfaction is guaranteed or your money back!

What We Like
Pure and organic wild ingredients
More effective than taking powder
Loaded with antioxidants for a strong immune response
Made in the USA with strict quality control
Satisfaction guaranteed or your money back
#TOP 9

NATURELO Mushroom Supplement for Brain & Immune Health

MUSH-90-FBM-US
NATURELO Mushroom Supplement for Brain & Immune Health Cover
NATURELO Mushroom Supplement – Brain & Immune Health Blend with Lion’s Mane, Reishi, Turkey Tail – 90 Vegan Friendly Capsules

Looking for a natural way to support your immune system and brain health? Try NATURELO Mushroom Supplement. It features three of the most well-researched functional mushrooms, including lion's mane, reishi, and turkey tail, known for their immune-boosting and brain-nourishing effects. The supplement is made from organic mushroom extracts with verified beta glucan levels, ensuring the potency of the beneficial active compound. It's also non-GMO, vegan-friendly, and free of gluten, dairy, or soy.

What We Like
Contains three well-researched functional mushrooms for immune and brain health.
Uses standardized mushroom extracts with confirmed beta glucan levels for potency.
Supports everyday immune health with antioxidants, nutrients, and beta glucan.
May help support normal, healthy brain and nerve cell function.
Derived from organic mushrooms with no added preservatives, coloring, or artificial additives.
#TOP 10

Real Mushrooms Lion's Mane Mushroom Supplement

RM-LM60C-AZN-CM
White
Real Mushrooms Lion's Mane Mushroom Supplement Cover
Lions Mane Mushroom Cognition Capsules (120 Capsules) Lions Mane Mushroom Powder Extract Capsules | Brain Supplement, Brain Vitamins, Focus Supplement

The Real Mushrooms Lion's Mane Mushroom Supplement is a non-GMO and gluten-free dietary supplement that provides unparalleled brain function with every capsule. Made from real lions mane mushroom extract, this supplement is hand-picked and analyzed by experts to ensure the best extract possible. It contains >30% beta-glucans and measured levels of beneficial compounds, providing overall health, wellness, and superior focus factor. With 1000 mg of extract in each serving, one bottle is already good for 2 months, making it an excellent value for your money.

What We Like
Hand-picked and analyzed by experts to ensure the best extract possible
Contains >30% beta-glucans and measured levels of beneficial compounds
Good for 2 months with 1000 mg of extract in each serving
Provides overall health, wellness, and superior focus factor
Non-GMO, gluten-free, vegan, dairy-free, nut-free, and organic
Buying Guide Image

Frequently Asked Questions (FAQs)

1. Are mushrooms supplements good for you?

“Some of the benefits you could expect from mushroom supplements include increased energy, improved muscle recovery, immune support, heart health, antioxidants, anti-inflammatory, and concentration or cognition.”

2. Which is the best mushroom supplement to take?

Our Picks for the Best Mushroom Supplements. Best Coffee Substitute: MUD/WTR.Best Overall: Medterra Wellness Capsules.Best Mushroom Powder: Four Sigmatic Mushroom Blend.Best Value: NOW Cordyceps 750 mg Veg Capsules.Best for Stress: Your Super Magic Mushroom Mix.Best for Cognitive Enhancement: Vital Plan Brain Boost.

3. What are the benefits of taking mushroom extract?

The potential health benefits modern science has looked into include:. Boosted Exercise Performance.Potential Anti-Tumor Effects.Anti-Aging Properties.Anti-Inflammatory.Immune System Boost.Anti-Cancer Properties.

4. Are mushroom powders effective?

Powders made with Chaga advertise that they're good for immunity and digestion. Often they come with tag lines like “immune support,” and “sacred antioxidants.” Cordyceps is usually tied to fitness and performance, with terms like “energy,” “stamina” and “endurance.”

Editor's Notes

During our natural mushrooms supplement research, we found 24 natural mushrooms supplement products and shortlisted 10 quality products. We collected and analyzed 281,194 customer reviews through our big data system to write the natural mushrooms supplements list. We found that most customers choose natural mushrooms supplements with an average price of $23.18.

The natural mushrooms supplements are available for purchase. We have researched hundreds of brands and picked the top brands of natural mushrooms supplements, including Kaya Naturals, The Genius Brand, DR. EMIL NUTRITION, Clean Nutraceuticals, Drops Of Nature. The seller of top 1 product has received honest feedback from 651 consumers with an average rating of 4.8.

Written by
Elisa Drew Avatar

Elisa Drew is a really professional copywriter specializing in baby products with five years of experience working as a pediatrician once. She has published a series of baby books purchased by over thirty thousand people in the United States.