Best Antiseptic Mouthwashes of 2025

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Antiseptic mouthwashes are a popular choice for individuals looking to maintain good oral hygiene. These products are designed to kill bacteria and germs that can cause bad breath, gum disease, and other oral health issues. They typically contain active ingredients such as alcohol, chlorhexidine, or hydrogen peroxide, which work to kill bacteria and freshen breath. Some antiseptic mouthwashes may also contain fluoride, which can help to strengthen tooth enamel and prevent tooth decay. Overall, antiseptic mouthwashes are a convenient and effective way to maintain good oral health and keep your mouth feeling fresh and clean.
At a Glance: Our Top Picks
Top 10 Antiseptic Mouthwashes
TheraBreath Deep Clean Mouthwash
TheraBreath Mouthwash offers a refreshing fresh mint flavor while effectively combating bad breath and oral health issues. This dentist-formulated mouthwash kills 99.9% of germs linked to bad breath, plaque, and gingivitis, ensuring you can smile with confidence. Unlike many mouthwashes, it is alcohol-free, which means you won’t experience any burning sensation while rinsing. It is also free from harmful additives like dyes, sulfates, and parabens, making it a safer choice for your daily oral care routine. With its vegan and gluten-free certification, this mouthwash caters to diverse dietary needs.
Amazon Basics Antiseptic Mouthwash Blue Mint
Amazon Basics Mouthwash is a 1.5-liter bottle of antiseptic rinse in a refreshing blue mint flavor. This mouthwash is designed to help you manage plaque buildup, which can lead to gingivitis, ensuring your gums stay healthy. It also improves your overall oral hygiene and effectively combats bad breath, giving you confidence throughout the day. For best results, use it morning and night. If you enjoy Listerine, you might find this alternative just as effective. Plus, with Alexa voice shopping, reordering is as easy as saying, “Alexa, reorder Amazon Basics Mouthwash.”
Colgate Peroxyl Antiseptic Mouthwash, 1.5% Hydrogen Peroxide, Mild Mint - 500ml
Colgate Peroxyl Antiseptic Mouthwash is a mouth rinse that helps cleanse and promote healing of minor oral wounds, such as oral sores and irritations. Its oxygenating action removes debris and soothes minor gum inflammation from dental procedures, dentures, and orthodontic appliances. With a mild mint flavor, this alcohol-free formula is perfect for those with sensitive mouths.
Amazon Basics Antiseptic Mouthwash
Amazon Mouthwash is a 1-liter antiseptic spring mint mouthwash that helps control plaque leading to gingivitis and kills germs causing gum disease. Its refreshing mint flavor leaves your mouth feeling clean and fresh. Using it morning and night can improve your oral hygiene. If you like Listerine Freshburst Antiseptic Mouthwash, Amazon Mouthwash is a great alternative. Alexa voice shopping enables you to reorder with ease, just say, “Alexa, reorder Amazon Basics Mouthwash." Amazon Basics offers a satisfaction guarantee, so if you aren't satisfied, they'll refund you for any reason within a year of purchase.
Listerine Freshburst Antiseptic Mouthwash, Spearmint, 1 L, Pack of 2
Get rid of bad breath and keep your mouth clean with Listerine Freshburst Antiseptic Mouthwash. This 2 pack of 1-liter bottles kills 99.9% of germs that cause plaque, gingivitis and bad breath. It's clinically shown to reduce 52% more plaque and 21% more gingivitis than brushing and flossing alone. The Freshburst spearmint flavor of this mouthwash leaves your mouth fresh and clean. It's ADA-accepted for fighting, preventing, and reducing plaque and gingivitis. Use it twice a day, both morning and night for 24-hour germ protection.
Amazon Basics Antiseptic Rinse, 1L
Amazon Basics Multi Action Antiseptic Rinse is a 1-liter bottle of mouthwash that helps control plaque leading to gingivitis. This alcohol-free mouthwash has a fresh mint flavor and is perfect for morning and night use to achieve better oral hygiene. It is Alexa voice shopping enabled and comes with a satisfaction guarantee. If you're a fan of Listerine Antiseptic Mouthwash, you will love Amazon Basics Multi Action Antiseptic Rinse.
Amazon Basics Antiseptic Mouthwash, 4-Pack
Amazon Basics Mouthwash is a pack of four 1.5-liter bottles of antiseptic original mouthwash that helps control plaque that leads to gingivitis. It kills germs that cause plaque and gum disease, ensuring better oral hygiene when used morning and night. The product has an original flavor and is Alexa voice shopping enabled, making it easier for you to reorder by just saying, “Alexa, reorder Amazon Basics Mouthwash." If you are a fan of Listerine Antiseptic Mouthwash, you should try Amazon Basics Multi Action Antiseptic Rinse. Amazon Basics also offers a satisfaction guarantee, promising to refund you for any reason within a year of purchase.
Listerine Original Antiseptic Mouthwash, 1L
Listerine Original Antiseptic Mouthwash is a germ-killing mouthwash that kills 99.9% of germs causing bad breath, plaque, and gingivitis. Clinically proven to reduce plaque and gingivitis more than brushing and flossing alone, it offers 24-hour germ protection with twice daily use. Its refreshing original flavor leaves your mouth feeling clean and fresh, and it's an ADA-accepted mouthwash. Use it twice daily by rinsing full strength for 30 seconds with 20 mL for optimal results.
Listerine Clinical Solutions Gum Health Mouthwash
Listerine Gum Health Mouthwash is designed to promote healthier gums and combat plaque buildup. This mouthwash effectively kills the germs responsible for gum issues, helping to reduce gingivitis in just one week. By using this rinse regularly, you can maintain your gum health for up to 12 weeks, surpassing the results of brushing alone. The formula, enriched with zinc, works to prevent stubborn plaque accumulation and reduces bacteria below the gumline. With a refreshing icy mint flavor, this mouthwash makes your oral care routine more enjoyable and effective.
Listerine Cool Mint Antiseptic Mouthwash, 1 L (Pack of 2)
Listerine Cool Mint Antiseptic Mouthwash is a germ-killing mouthwash for bad breath that comes in a pack of two 1-liter bottles. It kills 99.9% of germs that cause bad breath, plaque, and gingivitis, giving you fresh breath and germ protection. This ADA-accepted antiseptic mouthwash reduces plaque by up to 52% more than brushing and flossing alone and reduces gingivitis by 21% more. With approximately 2 months of supply, use it twice daily for 30 seconds to achieve maximum results and enjoy a refreshing and clean feeling.
During our antiseptic mouthwash research, we found 24 antiseptic mouthwash products and shortlisted 10 quality products. We collected and analyzed 509,312 customer reviews through our big data system to write the antiseptic mouthwashes list. We found that most customers choose antiseptic mouthwashes with an average price of $16.40.
The antiseptic mouthwashes are available for purchase. We have researched hundreds of brands and picked the top brands of antiseptic mouthwashes, including TheraBreath, Colgate, Listerine. The seller of top 1 product has received honest feedback from 385 consumers with an average rating of 4.7.

Elisa Drew is a really professional copywriter specializing in baby products with five years of experience working as a pediatrician once. She has published a series of baby books purchased by over thirty thousand people in the United States.