Best Antiseptic Mouthwashes of 2026

Name: Colgate Peroxyl Antiseptic Mouthwash, 1.5% Hydrogen Peroxide, Mild Mint - 500ml
Brand: Colgate

Elisa Drew

Last Updated: Jan 11, 2026

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Antiseptic mouthwashes are a popular choice for individuals looking to maintain good oral hygiene. These products are designed to kill bacteria and germs that can cause bad breath, gum disease, and other oral health issues. They typically contain active ingredients such as alcohol, chlorhexidine, or hydrogen peroxide, which work to kill bacteria and freshen breath. Some antiseptic mouthwashes may also contain fluoride, which can help to strengthen tooth enamel and prevent tooth decay. Overall, antiseptic mouthwashes are a convenient and effective way to maintain good oral health and keep your mouth feeling fresh and clean.

At a Glance: Our Top Picks

#TOP 1

Colgate Peroxyl Antiseptic Mouthwash, 1.5% Hydrogen Peroxide, Mild Mint - 500ml

9.9

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#TOP 2

Listerine Cool Mint Antiseptic Mouthwash, 1 L (Pack of 2)

9.8

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#TOP 3

TheraBreath Deep Clean Mouthwash

9.6

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Top 6 Antiseptic Mouthwashes

#TOP 1 Best Hydrogen Peroxide Mouthwash

Colgate Peroxyl Antiseptic Mouthwash, 1.5% Hydrogen Peroxide, Mild Mint - 500ml

Colgate
10035000320299
Blue

Colgate Peroxyl Antiseptic Mouthwash and Mouth Sore Rinse, 1.5% Hydrogen Peroxide, Mild Mint - 500ml, 16.9 Fluid Ounces

Colgate Peroxyl Antiseptic Mouthwash is a mouth rinse that helps cleanse and promote healing of minor oral wounds, such as oral sores and irritations. Its oxygenating action removes debris and soothes minor gum inflammation from dental procedures, dentures, and orthodontic appliances. With a mild mint flavor, this alcohol-free formula is perfect for those with sensitive mouths.

9.9

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What We Like

Fast canker sore relief
Gentle foaming action
Mild mint flavor
No alcohol or burning
Effective for mouth wounds

#TOP 2

Listerine Cool Mint Antiseptic Mouthwash, 1 L (Pack of 2)

Listerine
312547780292
Blue

Listerine Cool Mint Antiseptic Mouthwash, Kills 99.9% of Germs That Cause Bad Breath, Plaque & Gingivitis, ADA Accepted, Clinically Proven, Cool Mint Flavor, for Adults, 1L Bottles, 2 Pack

Listerine Cool Mint Antiseptic Mouthwash is a germ-killing mouthwash for bad breath that comes in a pack of two 1-liter bottles. It kills 99.9% of germs that cause bad breath, plaque, and gingivitis, giving you fresh breath and germ protection. This ADA-accepted antiseptic mouthwash reduces plaque by up to 52% more than brushing and flossing alone and reduces gingivitis by 21% more. With approximately 2 months of supply, use it twice daily for 30 seconds to achieve maximum results and enjoy a refreshing and clean feeling.

9.8

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What We Like

Long-lasting fresh breath
Effective germ and plaque removal
Invigorating cool mint flavor
Great value for size
Improves gum health

#TOP 3

TheraBreath Deep Clean Mouthwash

TheraBreath
697029010556
White

TheraBreath Deep Clean Mouthwash, Antiseptic Benefits, Fresh Mint Flavor, Dentist Formulated, Alcohol Free, 16 fl oz (Pack of 2)

TheraBreath Mouthwash offers a refreshing fresh mint flavor while effectively combating bad breath and oral health issues. This dentist-formulated mouthwash kills 99.9% of germs linked to bad breath, plaque, and gingivitis, ensuring you can smile with confidence. Unlike many mouthwashes, it is alcohol-free, which means you won’t experience any burning sensation while rinsing. It is also free from harmful additives like dyes, sulfates, and parabens, making it a safer choice for your daily oral care routine. With its vegan and gluten-free certification, this mouthwash caters to diverse dietary needs.

9.6

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What We Like

Alcohol-free formula
Eliminates bad breath germs
Gentle on the mouth
Vegan and gluten-free

#TOP 4

Listerine Freshburst Antiseptic Mouthwash, Spearmint, 1 L, Pack of 2

Listerine
Green

Listerine Freshburst Antiseptic Mouthwash for Bad Breath, Kills 99.9% of Bad Breath Germs & Fights Plaque & Gingivitis, ADA Accepted Mouthwash, Spearmint, Convenience Pack, 2 x 1 L

Get rid of bad breath and keep your mouth clean with Listerine Freshburst Antiseptic Mouthwash. This 2 pack of 1-liter bottles kills 99.9% of germs that cause plaque, gingivitis and bad breath. It's clinically shown to reduce 52% more plaque and 21% more gingivitis than brushing and flossing alone. The Freshburst spearmint flavor of this mouthwash leaves your mouth fresh and clean. It's ADA-accepted for fighting, preventing, and reducing plaque and gingivitis. Use it twice a day, both morning and night for 24-hour germ protection.

9.6

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What We Like

Fresh clean feeling
Effective bad breath solution
Fast acting and easy to use
Long-lasting freshness

#TOP 5

Listerine Original Antiseptic Mouthwash, 1L

Listerine
PPAX1256840
Yellow

Listerine Original Antiseptic Oral Care Mouthwash to Kill 99.9% of Germs That Cause Bad Breath, Plaque and Gingivitis, ADA-Accepted Mouthwash, Original Flavored Oral Rinse, 1 L

Listerine Original Antiseptic Mouthwash is a germ-killing mouthwash that kills 99.9% of germs causing bad breath, plaque, and gingivitis. Clinically proven to reduce plaque and gingivitis more than brushing and flossing alone, it offers 24-hour germ protection with twice daily use. Its refreshing original flavor leaves your mouth feeling clean and fresh, and it's an ADA-accepted mouthwash. Use it twice daily by rinsing full strength for 30 seconds with 20 mL for optimal results.

9.5

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What We Like

Kills 99.9% of germs causing bad breath, plaque, and gingivitis
Clinically proven to reduce plaque and gingivitis more than brushing and flossing alone
Offers 24-hour germ protection with twice daily use

#TOP 6

Amazon Basics Blue Mint Antiseptic Mouthwash, 1L

Amazon Basics
ghh5
Blue

Amazon Basics Antiseptic Mouthwash, Blue Mint, 1 Liter, 33.8 Fluid Ounces, 1-Pack (Previously Solimo)

Improve your oral hygiene and control bad breath with Amazon Basics Blue Mint Antiseptic Mouthwash. This 1-liter bottle helps control plaque that leads to gingivitis, leaving you with a healthier mouth. The blue mint flavor provides a refreshing sensation while you rinse, and using it morning and night will keep your mouth feeling fresh all day. Alexa voice shopping enables you to reorder with ease, and the satisfaction guarantee ensures you can try it risk-free.

9.4

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What We Like

Good value for money
Works just as well as name brand
Long-lasting freshness
Similar taste to Listerine
Versatile for use with water flosser

Editor's Notes

During our antiseptic mouthwash research, we found 24 antiseptic mouthwash products and shortlisted 6 quality products. We collected and analyzed 964,988 customer reviews through our big data system to write the antiseptic mouthwashes list. We found that most customers choose antiseptic mouthwashes with an average price of $11.42.

The antiseptic mouthwashes are available for purchase. We have researched hundreds of brands and picked the top brands of antiseptic mouthwashes, including Colgate, Listerine, TheraBreath. The seller of top 1 product has received honest feedback from 384 consumers with an average rating of 4.7.

Written by

Elisa Drew

Elisa Drew is a really professional copywriter specializing in baby products with five years of experience working as a pediatrician once. She has published a series of baby books purchased by over thirty thousand people in the United States.