Best L-Arginine Supplements for Cholesterol Support of 2026

Elisa Drew Avatar
Elisa Drew
Last Updated: Jan 13, 2026

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L-Arginine supplements are a popular choice for those looking to support their cholesterol levels. L-Arginine is an amino acid that helps to produce nitric oxide, which can help to relax blood vessels and improve blood flow. This can lead to a reduction in cholesterol levels, as well as improved cardiovascular health. L-Arginine supplements are available in a variety of forms, including capsules, powders, and tablets, and can be found at many health food stores and online retailers. As with any supplement, it is important to speak with a healthcare provider before adding L-Arginine to your routine.

At a Glance: Our Top Picks

NOW Supplements L-Arginine 1000mg Tablets Cover #TOP 1
NOW Supplements L-Arginine 1000mg Tablets
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Nature's Bounty L-Arginine Tablets Cover #TOP 2
Nature's Bounty L-Arginine Tablets
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HAVASU NUTRITION L-Arginine L-Citrulline Nitric Oxide Supplement Cover #TOP 3
HAVASU NUTRITION L-Arginine L-Citrulline Nitric Oxide Supplement
ftb score rating icon 9.6

Top 10 L-Arginine Supplements for Cholesterol Support

NOW Supplements L-Arginine 1000mg Tablets

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NOW Supplements L-Arginine 1000mg Tablets Cover
NOW Foods Supplements, L-Arginine 1,000 mg, Nitric Oxide Precursor*, Amino Acid, 120 Tablets

The NOW Supplements L-Arginine 1000mg Tablets are a non-GMO, double-strength supplement that supports vascular health and metabolism management. Arginine is an important precursor of nitric oxide, which plays a role in the dilation of blood vessels. The product is pharmaceutical-grade, and the tablets come in a bottle of 120-count. The product is also Kosher, Soy-free, and gluten-free. However, customers are advised to be available during product delivery to prevent damage due to exposure to heat or sunlight.

What We Like
Effective amino acid support
Improved workout performance
Enhanced circulation and recovery
Great value per bottle
Consistent product quality

Nature's Bounty L-Arginine Tablets

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Nature’s Bounty L-Arginine 1000mg for Supporting Blood Flow and Vascular Function – Non-GMO, Gluten Free, 50 Tablets

Improve your heart health with Nature's Bounty L-Arginine. This supplement supports nitric oxide synthesis and circulation, which helps to promote healthy blood flow and heart function. As a protein building block, it also contributes to healthy muscles. The tablets are vegetarian and gluten-free, making them easy to incorporate into any diet. However, customers are advised to be available during delivery to avoid heat or sunlight exposure, which may damage the product.

What We Like
Improved blood flow
Enhanced workout performance
Supports heart health
Increased male vitality
Non-GMO, no artificial additives

HAVASU NUTRITION L-Arginine L-Citrulline Nitric Oxide Supplement

HAVASU NUTRITION L-Arginine L-Citrulline Nitric Oxide Supplement Cover
L-Arginine Capsules with L-Citrulline - Nitric Oxide Supplement - L Arginine and L Citrulline Blend - 60 Count - Vegan, Non-GMO Capsules for Performance, Endurance and Muscle Support - 1 Month Supply

HAVASU NUTRITION L-Arginine L-Citrulline Nitric Oxide Supplement is a vegan capsule supplement that provides an ultimate blend of L-arginine, L-citrulline, and beetroot powder, which are necessary for optimal pump, growth, and endurance. The high dosage of nitric oxide precursors in this supplement helps to increase blood flow and circulation, making it the perfect pre-workout supplement for men. With an optimal blood flow supplement, you can achieve a bulk muscle look and quick recovery. This blend is stronger than other leading brands, making it the best blood circulation supplement to help you become an alpha prime male.

What We Like
Improved circulation and blood flow
Gentle, non-stimulant energy boost
Supports workout performance and stamina
Easy to take capsules
Synergistic L-Arginine & L-Citrulline blend

Best Naturals L-Arginine Supplement

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Best Naturals L-Arginine Supplement Cover
(New Improved Formula) Best Naturals L-Arginine 1000 mg 120 Tablets - Pharmaceutical Grade L Arginine Supplement Promotes Nitric Oxide Synthesis

The Best Naturals L-Arginine Supplement is a great product to promote nitric oxide synthesis and support heart health. Each tablet contains 1000mg of L-Arginine and the bottle includes 120 tablets. The product is non-GMO, gluten-free, and has been 3rd party lab tested for purity and quality. It is proudly made in the USA, in a GMP compliant and FDA registered facility. Additionally, the product is free of artificial colors, flavors, sweeteners, and preservatives, as well as common allergens such as milk, soy, and wheat.

What We Like
Improved circulation support
Boosts energy and strength
Affordable price point
GMP certified quality
Supports men's health

Puritan's Pride L-arginine Capsules

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Puritan's Pride L-Arinine 1000mg, Dietary Supplement Supports Nitric Oxide Levels and Heart and Circulatory Heath, 100 Day Supply, 100 Tablets

Get the most out of your workouts and boost your immune system with Puritan's Pride L-arginine 1000 Mg Capsules. Arginine serves as a source of energy and supports exercise effects, and is one of the most important amino acids in immune function. Be mindful of product delivery as exposure to heat or sunlight may lead to melting or damage. This unflavored supplement comes in a bottle of 100 count capsules, making it convenient for adult use.

What We Like
Improved workout performance
Enhanced blood flow
No aftertaste
Easy to swallow
High-quality supplement
#TOP 6

Nutricost L-Arginine 1000mg Tablets

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Nutricost L-Arginine 1000mg, Amino Acid Tablets (150 Tablets)

The Nutricost L-Arginine 1000mg Tablets come in a bottle of 150 tablets, with each tablet containing 1000mg of L-Arginine. This supplement is double strength and non-GMO, soy-free, and gluten-free. It is made in a GMP compliant, FDA registered facility, ensuring quality and safety. One bottle provides 150 servings of L-Arginine, which can potentially improve blood flow, exercise performance, and immune system function.

What We Like
Effective energy boost
Good value price
Easy to take
Quality ingredients
#TOP 7

Nutricost L-Arginine L-Citrulline Capsules

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Nutricost L-Arginine L-Citrulline Complex 750mg, 240 Capsules - Non-GMO

Get the perfect combination of L-Arginine and L-Citrulline with Nutricost's high quality supplement. Each capsule contains 500mg of L-Arginine and 250mg of L-Citrulline, providing 750mg per capsule. This potent free-form amino acid combination comes in a 240 capsule bottle, and is non-gmo, gluten-free and 3rd party tested for safety and quality. Made in a GMP compliant, FDA registered facility, this supplement is perfect for adults who want to improve their overall well-being and performance.

What We Like
Contains a powerful blend of L-Arginine and L-Citrulline
Non-GMO, gluten-free, and 3rd party tested for safety and quality
Comes in a 240 capsule bottle, providing a long-lasting supply
Made in a GMP compliant, FDA registered facility
#TOP 8

Force Factor L-Arginine Nitric Oxide Supplement

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Force Factor L-Arginine Nitric Oxide Supplement with BioPerine to Help Build Muscle and Support Stronger Blood Flow, Circulation, Nutrient Delivery, and Pumps, L-Arginine 3000mg, 3g, 150 Capsules

Force Factor L-Arginine Nitric Oxide Supplement is designed to strengthen blood flow, provide an optimal daily dose of 3000mg of L-Arginine, and ensure superior absorption with BioPerine. This supplement is ideal for enhancing performance, delivering essential nutrients and oxygen to muscles, and supporting nutrient delivery and pumps. Additionally, it is formulated to stack well with other Force Factor supplements and is produced in cGMP facilities in the USA with high-quality ingredients sourced from all over the world.

What We Like
Easier to swallow
Increases energy and clarity
Improves blood flow
Supports muscle growth
#TOP 9

Thorne Perfusia-SR L-Arginine Capsules

Thorne Research
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THORNE - L-Arginine Sustained Release (Formerly Perfusia-SR) - Support Heart Function, Nitric Oxide Production & Optimal Blood Flow* - 60 Servings

Sustained-release Thorne Perfusia-SR L-arginine capsules support heart health, nitric oxide production, wound healing, immune function and optimal blood flow. With twice-daily dosing, these capsules promote relaxation of arteries and support lean muscle mass and work capacity during exercise. Additionally, every Thorne product is made with the purest possible ingredients, without gluten or other major allergens, soy, dairy, shellfish, or fish. Thorne adheres to the FDA’s current Good Manufacturing Practices (cGMPs) and has the highest number of NSF Certified for Sport products which tests for more than 200 banned substances for elite athletic competitions.

What We Like
Effective for blood pressure control
Natural supplement backed by research
No significant side effects
Trustworthy quality product
Improves bruising recovery time
#TOP 10

NOW L-Arginine 500mg, 250 Capsules

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NOW L-Arginine 500mg, 250 Capsules Cover
NOW Foods Supplements, L-Arginine 500 mg, Nitric Oxide Precursor*, Amino Acid, 250 Veg Capsules

NOW L-Arginine 500mg is a non-GMO, kosher, and soy-free amino acid supplement, involved in urea metabolism, protein production, and blood vessel dilation. The product is GMP quality assured, ensuring compliance with sanitation, processing, documentation, and testing requirements for consistent and safe product quality. NOW L-Arginine is packaged by a family-owned business in the USA since 1968.

What We Like
Nitric oxide support
Improved energy levels
Convenient dosage
Enhanced recovery
Quality assurance
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Frequently Asked Questions (FAQs)

1. Is L-arginine good for lowering cholesterol?

The most recent research suggests that L-arginine may lower blood pressure, improve cholesterol and improve overall blood vessel health.

2. Does L-arginine help with arteries?

Some evidence shows that arginine may help improve blood flow in the arteries of the heart. That may improve symptoms of clogged arteries, chest pain or angina, and coronary artery disease.

3. Is L-arginine good to take everyday?

L-arginine is considered to be generally safe. It might be effective at lowering blood pressure, reducing the symptoms of angina and PAD , and treating erectile dysfunction due to a physical cause.

4. Who should not take L-arginine?

For example, those with asthma, cirrhosis of the liver, kidney disease, low blood pressure, and guanidinoacetate methyltransferase deficiency — an inherited disorder that affects arginine metabolism, should avoid L-arginine due to the potential for adverse effects (22).

Editor's Notes

During our l-arginine supplement for cholesterol support research, we found 24 l-arginine supplement for cholesterol support products and shortlisted 10 quality products. We collected and analyzed 451,504 customer reviews through our big data system to write the l-arginine supplements for cholesterol support list. We found that most customers choose l-arginine supplements for cholesterol support with an average price of $19.08.

The l-arginine supplements for cholesterol support are available for purchase. We have researched hundreds of brands and picked the top brands of l-arginine supplements for cholesterol support, including NOW Foods, Nature's Bounty, HAVASU NUTRITION, Best Naturals, Puritan's Pride. The seller of top 1 product has received honest feedback from 384 consumers with an average rating of 4.7.

Written by
Elisa Drew Avatar

Elisa Drew is a really professional copywriter specializing in baby products with five years of experience working as a pediatrician once. She has published a series of baby books purchased by over thirty thousand people in the United States.