Best Dry Eye Relief Products of 2025

Ocusoft Retaine MGD Ophthalmic Emulsion is a preservative-free solution that moisturizes, lubricates, and protects moderate to severe dry eyes. This product utilizes Nova orb technology that effectively delivers ingredients through electrostatic attraction, which provides long-lasting relief. The emulsion's hypo tonicity adds moisture by lowering the salt concentration of tears, while the lipid component lubricates and protects the surface of the eye.

Systane Eye Ointment is the #1 Dr Recommended Brand of Artificial Tears, providing nighttime relief for dry eye symptoms. The ointment soothes and protects against dry, irritated eyes, forming a long-lasting, protective layer while you sleep. This preservative-free formula ensures safety for your eyes.

OPTASE Dry Eye Intense Drops are preservative-free eye drops that are designed to moisturize, protect, and hydrate your eyes to improve tear quality. Its long-lasting formulation provides relief from moderate to severe dry eye symptoms and post-operative symptoms. The advanced multi-use drop bottle maintains sterility for up to 3 months without preservatives, making it convenient for use while on the go. OPTASE is recommended by doctors for tackling the cause and symptoms of Dry Eyes, Blepharitis, and Meibomian Gland Dysfunction (MGD).

iVIZIA Sterile Lubricant Eye Drops are a moisturizing and preservative-free solution designed for dry eye relief. The unique formulation includes hydrating polymers, moisturizing hyaluronic acid, and trehalose for long-lasting moisture. The patented ABAK bottle allows for easy dispensing drop-by-drop, without streaming, and is contact lens friendly. The bottle is also ergonomic, easy to open, hold, and squeeze.

TheraTears Extra Dry Eye Therapy Lubricating Eye Drops provide up to 12 hours of hydration and comfort for dry eyes. This one-of-a-kind silky hydration helps to rehydrate, protect against further irritation, and support a natural tear pH level. It contains the 5 vital electrolytes found in natural tears and corrects the salt imbalance that can cause dry eye symptoms. Customers have found this product to be helpful in relieving dry eyes, with some noting that it is more viscous than other brands and lasts longer.

Systane Hydration eye drops provide long-lasting relief for dry eyes with advanced hydration from hyaluronate. These preservative-free drops are safe for use with all contact lenses and extra moisturizing for sensitive eyes. Clinically proven to protect and soothe dry eye symptoms.

The OTBK Eye Humidifier is designed to provide quick relief for dry and fatigued eyes. It acts as a cleanser, moisturizer, and treatment, ensuring your eyes remain hydrated and comfortable throughout the day. If you spend long hours in front of screens or often wear contact lenses, this device can help alleviate discomfort and eye strain. Its multifunctionality allows it to serve as a portable nebulizer and face steamer, making it a versatile addition to your daily routine. Plus, it’s easy to use—just fill it with water or diluted eye drops, press a button, and enjoy instant moisture.

TheraTears Dry Eye Therapy Lubricant Eye Drops, Preservative Free, provide immediate, long-lasting relief of dry eye symptoms. Created by an ophthalmologist after 18 years of research, these drops contain the 5 vital electrolytes found in natural tears and are preservative free for sensitive eyes. Customers praise the product for its soothing effects and its ability to provide relief from dry eye symptoms. However, some customers have noted that the single-use vials can be sharp and poke the eye if not handled carefully.

Blink NutriTears Supplement offers effective hydration for your eyes from the inside out. It targets the main causes of dry eyes, promoting healthier tear production. With its unique blend of ingredients like lutein and vitamin D, you can experience continuous relief from dryness, allowing your eyes to function comfortably throughout the day. This supplement helps keep your eyes moisturized for a longer duration, making it easier for you to focus on your daily tasks without discomfort.

LUMIFY Eye Drops effectively tackle red eyes, helping you achieve a brighter and whiter appearance. These drops work quickly, reducing redness in just one minute and lasting up to eight hours. Unlike other over-the-counter eye drops, LUMIFY contains brimonidine, which specifically targets redness while minimizing potential side effects. Being FDA approved and free from bleach and dyes, you can trust that these drops are safe for your eyes. With over 150 years of expertise in eye care from Bausch and Lomb, you can feel confident in using LUMIFY to enhance your natural beauty.