Best Poison Ivy Treatments of 2026

"I found this cream to be very effective for relieving the itching from my psoriasis. The menthol delivers a cooling sensation that really soothes my skin during flare-ups. It's also non-greasy and budget-friendly."

"My dermatologist suggested this lotion for my neuropathy pain, and it's been a real help. The lightweight, non-greasy texture absorbs fast, and it eases the soreness on my feet at night. It's not a cure, but definitely offers soothing relief."

"The lotion itself is excellent at stopping itching and soothing dry skin. However, the pump can be tricky—it stopped working halfway through, making it tough to get the rest out. Still, the lotion's quality makes it worth the effort."

"I was desperate for relief after an allergic reaction left my arm unbearably itchy. As soon as I applied this lotion, the itching vanished instantly! I was so impressed I immediately ordered a second bottle. This stuff is a total game changer!"

"After spending a night outdoors, I ended up with dozens of mosquito bites. This calamine lotion was a lifesaver—it not only stopped nearly all the itching but also helped dry out the bites and speed up healing. The formula is thicker than other brands, making it much easier to use. Absolutely worth every penny!"

"I’ve tried countless products for bug bites and nothing came close to this. Caladryl lotion worked fast and dried up my No-See-Um bites quickly. Even though it leaves pink dots on my skin, the relief from constant itching is so worth it. Highly recommended!"

"I've tried many products, but this one has been exceptional at protecting my baby from rashes and even helped with my own. Highly recommend it for anyone dealing with skin irritation."

"Whenever I experience dyshidrotic eczema, this ointment instantly relieves the burning itch and helps blisters heal fast. My dermatologist was even impressed with the results."

"This is so much more effective than standard ointments for my baby's diaper rash and eczema. Visible improvement happens within hours."

"I struggled with persistent ear eczema and recurring MRSA infections, especially during pregnancy. After countless doctor visits and expensive prescriptions that barely helped, Domeboro made a huge difference. Within days, my symptoms improved dramatically—the constant itching and crusting stopped, and I finally got some relief. It truly felt like a lifesaver."

"Nothing I've tried has worked as well on poison ivy as this. With Domeboro, I experienced almost instant relief when I brushed it on my legs. It's a bit messy, but the results were totally worth it."

"I developed an intense itch from an allergic reaction, and even prescription-strength ointments couldn't help. Domeboro provided immediate and lasting relief—it was like a miracle for my skin."

"I always keep this on hand because it’s the most reliable solution whenever I get exposed to poison ivy. It’s incredibly simple to use—just follow the washing directions and the relief is almost immediate. It saves me from pain, discomfort, and unnecessary medical bills. After a lineman recommended it to me years ago, I would never be without it."

"I’ve tried nearly everything for poison ivy, from gasoline to brake cleaner, but this ointment ended up being the only thing that really worked. It stops the itching for hours and helped my rash heal without any medication or steroids. I use it every time I’m in the woods. While it can feel a bit rough on the skin, I’m convinced it’s the most effective at removing the oil. Now I just wish it was a bit cheaper or came in a bigger tube!"

"After accidentally coming into contact with poison ivy, I tried various pharmacy products with no luck. As soon as I applied this scrub, the rashes and itching began to fade within hours. My usual two to three week reaction was cut down significantly. It’s so effective that I’ll always keep it stocked at home from now on."

"Whenever my family gets mosquito bites, I always reach for this cream. It calms the itch quickly and isn’t greasy at all. The cream goes on white so it’s easy to see where you’re applying, but it dries clear and works fast."

"This is a reliable solution for stubborn itching. It acts within minutes and the extra strength formula really makes a difference. I keep it handy for emergencies because it’s a trusted product."

"I was surprised by how immediately it stops itching from insect bites. I’m happy with the results and definitely think it’s worth every penny."

"I struggled with poison ivy at the end of summer, and calamine lotion was useless. This cream was a total lifesaver—it soothed the itch almost immediately, reduced swelling and redness, and stayed on really well."

"Whenever I get poison ivy or bug bites, this is my go-to solution. It acts quickly, lasts long, and always dries up the rash fast."

"While this cream felt soothing right after application, the relief didn't last long for me. The itching returned quickly, so it didn't provide the long-term relief I was hoping for."

"I've struggled with poison ivy since childhood, and nothing worked as well as this soap. Within 24 hours, the itching stopped and the rash stopped spreading. It cleared up faster than any other product I’ve used before. I’ll definitely be stocking up for summer!"

"After my sister recommended this soap, I tried it on my poison ivy breakout. The itching and redness faded overnight, and now I always keep a bar handy when working outdoors. It’s become a must-have for me."

"My husband developed a bad poison ivy rash and this soap was a lifesaver. He noticed a dramatic improvement, especially when letting it dry on his skin. It helped reduce discomfort and symptoms, making his day much easier."

"I bought this for my husband when he developed a mysterious rash on his chest. After trying it, the relief was almost immediate—no need for a doctor visit. The spray is easy to apply and definitely worth a shot."

"After a nasty run-in with poison ivy, I sprayed this on and, while it has a pretty strong smell, it instantly cooled the itch. After a week, the rash was almost gone. I used to deal with these rashes for weeks, but this spray made a clear difference. Highly recommended!"

"Living on a farm surrounded by poison ivy, I keep this handy. It stops the itching fast and helps the rash dry out quickly—what used to be weeks of discomfort is now over in just days. Best product I’ve found for poison ivy."

"I've relied on these wipes for years, especially when I'm working outdoors or out camping. They’re incredibly handy, effective, and never harm my clothes, gear, or even my dog’s fur. Not having to lug around a bottle is a huge advantage for me."

"As a Search and Rescue volunteer, these wipes are a must-have in my kit. One wipe covers my face, neck, arms, and even my equipment. The individual packs let me easily share with teammates who might have poison oak exposure. For us, they’re a real lifesaver."

"After decades without a problem, I finally ran into a horrible poison ivy reaction. These wipes became my go-to solution for cleaning myself, my dog, and every surface I might have touched. They truly helped me control the situation and gave me peace of mind during a really tough time."