Best Antibacterial Denture Cleansers of 2026

Elisa Drew Avatar
Elisa Drew
Last Updated: Jan 13, 2026

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Antibacterial denture cleansers are a popular choice for those looking to keep their dentures clean and free from harmful bacteria. These cleansers are specially formulated to kill bacteria and remove stains, leaving dentures looking and feeling fresh. They come in different forms, including tablets, powders, and liquids, making them easy to use and convenient for most people. Some of these cleansers even come with added benefits like fresh breath and improved oral health. Overall, antibacterial denture cleansers are a great investment for anyone looking to maintain the cleanliness and hygiene of their dentures.

At a Glance: Our Top Picks

Polident 3 Minute Antibacterial Cleanser Tablets 180 Count Cover #TOP 1
Polident 3 Minute Antibacterial Cleanser Tablets 180 Count
ftb score rating icon 9.8
Polident 3 Minute Antibacterial Cleanser Tablets 60 Count Cover #TOP 2
Polident 3 Minute Antibacterial Cleanser Tablets 60 Count
ftb score rating icon 9.7
Polident Overnight Whitening Dental Appliance Cleanser Tablets 90 Count 2 Pack Cover #TOP 3
Polident Overnight Whitening Dental Appliance Cleanser Tablets 90 Count 2 Pack
ftb score rating icon 9.5

Top 7 Antibacterial Denture Cleansers

#TOP 1

Polident 3 Minute Antibacterial Cleanser Tablets 180 Count

Polident 3 Minute Antibacterial Cleanser Tablets 180 Count Cover
Polident 3 Minute Antibacterial Dental Appliance Cleanser Tablets, 90 Count (2 Pack)

The Polident Antibacterial Cleanser Tablets come in two boxes with 90 tablets each, giving you plenty of supply for your dental appliance care. This product features an improved formula that uses active power bubbles to reach and clean even the toughest spots on your dentures, retainers, or mouthguards. It kills 99.9% of odor-causing bacteria, helping to keep your appliance fresh and odor-free for longer. Designed specifically for various dental appliances including full and partial dentures, retainers, and aligners, these tablets provide a reliable and easy way to maintain your dental hygiene. Just soak, brush, rinse, and you're ready to go.

What We Like
Quick cleaning action
Kills 99.9% bacteria
No aftertaste or residue
Effective stain and odor removal
Good value pack
#TOP 2

Polident 3 Minute Antibacterial Cleanser Tablets 60 Count

Polident 3 Minute Antibacterial Cleanser Tablets 60 Count Cover
Polident 3 Minute Antibacterial Dental Appliance Cleanser Tablets, 60 Count

The Polident 3 Minute Cleanser offers a quick and effective way to clean your dental appliances. With 60 tablets included, you have plenty of supply to keep your retainers, dentures, or mouthguards fresh. Its improved formula features active power bubbles that reach even the toughest spots, ensuring a thorough clean. This cleanser also kills 99.9% of odor-causing bacteria, helping to keep your dental devices smelling fresh for longer. Designed for various dental appliances, it provides a deep, gentle clean that protects your items while making your daily routine easier.

What We Like
Quick cleaning time
Effective stain removal
No residue or odor
Fresh minty scent
Safe for dentures and retainers
#TOP 3

Polident Overnight Whitening Dental Appliance Cleanser Tablets 90 Count 2 Pack

Polident Overnight Whitening Dental Appliance Cleanser Tablets 90 Count 2 Pack Cover
Polident Overnight Whitening Antibacterial Dental Appliance Cleanser Tablets, 90 Count (2 Pack)

The Polident Whitening Cleanser Tablets offer a powerful cleaning solution for your dental appliances. With an improved formula featuring active power bubbles, these tablets reach even the most difficult spots, ensuring a thorough clean. You can trust these tablets to eliminate 99.9% of odor-causing bacteria, which helps keep your retainer or denture fresh and odor-free for longer periods. Plus, the cleanser removes stains effectively without the need for brushing, saving you time and effort while maintaining the appearance of your dental appliance. The Polident Whitening Cleanser Tablets are an easy and efficient way to keep your dental devices clean and fresh every day.

What We Like
Effective cleaning performance
Easy to use
Antibacterial protection
Subtle whitening effect
Good value multi-pack
#TOP 4

Efferdent Retainer Cleaning Tablets

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Efferdent Retainer Cleaning Tablets Cover
Efferdent Retainer Cleaning Tablets, Denture Cleaning Tablets for Dental Appliances, Minty Fresh & Clean, 126 Count

Efferdent Cleaning Tablets are a convenient solution for keeping your dental appliances clean and fresh. Whether you have retainers, full-plate dentures, partials, aligners, or other dental appliances, these tablets are designed to effectively remove plaque build-up and kill odor-causing bacteria. With just a 3-minute cleaning, they can eliminate 99.99% of bacteria, leaving your appliances fresh and ready to use. The powerful oxi-action formula also helps to remove stubborn stains in hard-to-reach places, ensuring a thorough clean. Plus, the minty fresh flavor not only cleanses your dental appliances but also leaves them with a refreshing taste. With Efferdent Cleaning Tablets, you can maintain the cleanliness and hygiene of your dental appliances effortlessly.

What We Like
Effective cleaning power
Removes odor and stains
Easy and quick to use
Affordable price
Convenient for daily routine
#TOP 5

Polident Overnight Whitening Cleanser Tablets, 60 Count

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Polident Overnight Whitening Cleanser Tablets, 60 Count Cover
Polident Overnight Whitening Antibacterial Dental Appliance Cleanser Tablets, 60 Count

The Polident Whitening Cleanser offers a convenient way to keep your dental appliances clean and fresh. With 60 tablets in the pack, you get long-lasting use. The improved formula uses powerful bubbles to reach and clean even the toughest spots, ensuring a thorough clean. This cleanser kills 99.9% of odor-causing bacteria, helping you maintain a fresher appliance for longer periods. Plus, it removes stains effectively without the need for brushing, saving you time and effort while keeping your dentures, retainers, or aligners looking their best.

What We Like
Effective stain removal
Kills odor-causing bacteria
Deep cleaning bubbles
Suitable for various appliances
Large 60-count pack
#TOP 6

Efferdent Retainer Cleaning Tablets, 126 Tablets

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Multicolor
Efferdent Retainer Cleaning Tablets, 126 Tablets Cover
Efferdent Denture Cleaner Tablets – Dental Appliances, Aligners, Mouth Guard, and Retainer Cleaner Tablets, Complete Clean, 126 Count

Use Efferdent Retainer Cleaning Tablets daily to clean retainers, full-plate dentures, partials, aligners, and other dental appliances. The Complete Clean formula kills 99.99% of odor-causing bacteria in 3 minutes while being gentle and non-abrasive. The powerful oxi-action of the tablets removes stubborn stains in hard-to-reach places and fights plaque build-up. Efferdent Retainer Cleaning Tablets leave dental appliances fresh and ready-to-use.

What We Like
Easy daily cleaning process
Prevents odor and buildup
No strong aftertaste or scent
Affordable and budget-friendly
Works on multiple appliances
#TOP 7

Polident Smokers Antibacterial Cleanser Tablets 90 Count

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90 Count
Polident Smokers Antibacterial Cleanser Tablets 90 Count Cover
Polident Smokers Antibacterial Dental Appliance Cleanser Tablets, 90 Count

The Polident Smokers Cleanser offers a powerful cleaning solution designed especially for dental appliances. With its new improved formula, it creates active bubbles that reach every corner of your dentures, ensuring a thorough clean. This cleanser kills 99.9% of bacteria that cause odors, helping you keep your dental appliance fresh throughout the day. It is also effective at removing tough stains from coffee, tea, and tobacco, giving your appliance a brighter, cleaner look. Using this product means you can enjoy a fresher, cleaner dental appliance with less effort and more confidence.

What We Like
Powerful active bubbles
Kills 99.9% odor bacteria
Removes tough coffee and tobacco stains
Suitable for various dental appliances
Dentist recommended brand
Buying Guide Image

Frequently Asked Questions (FAQs)

1. How do you clean bacteria off dentures?

You can use common household items to sanitise them. All you need for this option is the microwave in your kitchen! This is because scientists have found that microwaving dentures can kill off any MRSA bacteria that are present. Simply microwave your set of dentures for three minutes each week.

2. Can you use antibacterial soap on dentures?

Denture-wearers should maintain good oral hygiene by following these steps: Dentures should be rinsed after eating. Use a soft toothbrush, nailbrush, or denture brush to clean your dentures at least once a day and use dish soap, liquid antibacterial soap, or denture cleanser to remove any debris.

3. Can you disinfect dentures?

Brush your dentures at least daily. Soak and brush them with a soft-bristled brush and nonabrasive denture cleanser to remove food, plaque and other deposits. If you use denture adhesive, clean the grooves that fit against your gums to remove any remaining adhesive. Don't use denture cleansers inside your mouth.

4. Are denture tablets antibacterial?

Promote good oral hygiene by keeping your dentures in prime condition with the Antibacterial Denture Tablets from up & up™. These antibacterial denture cleaning tablets easily dissolve in water to remove tough stains, while killing up to 99.99% of odor-causing bacteria to give you a clean and confident smile.

Editor's Notes

During our antibacterial denture cleanser research, we found 24 antibacterial denture cleanser products and shortlisted 7 quality products. We collected and analyzed 413,103 customer reviews through our big data system to write the antibacterial denture cleansers list. We found that most customers choose antibacterial denture cleansers with an average price of $15.83.

The antibacterial denture cleansers are available for purchase. We have researched hundreds of brands and picked the top brands of antibacterial denture cleansers, including Polident, efferdent. The seller of top 1 product has received honest feedback from 384 consumers with an average rating of 4.7.

Written by
Elisa Drew Avatar

Elisa Drew is a really professional copywriter specializing in baby products with five years of experience working as a pediatrician once. She has published a series of baby books purchased by over thirty thousand people in the United States.