Best Denture Cleansers of 2026

Elisa Drew Avatar
Elisa Drew
Last Updated: Jan 13, 2026

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Denture cleansers are products specifically designed to clean and maintain dentures. They come in various forms such as tablets, powders or solutions, and are formulated to remove stains, plaque, and bacteria from dentures. Denture cleansers are easy to use and provide effective cleaning without damaging the dentures. They are a great way to keep dentures looking and feeling fresh, and to prevent bad breath and oral infections. Denture cleansers are available in most pharmacies and can be used on a regular basis to ensure optimal oral health.

At a Glance: Our Top Picks

M3 Naturals Retainer Cleaner Tablets 4 Month Supply Cover #TOP 1
M3 Naturals Retainer Cleaner Tablets 4 Month Supply
ftb score rating icon 9.8
Retainer Brite Tablets Cover #TOP 2
Retainer Brite Tablets
ftb score rating icon 9.7
Polident 3 Minute Antibacterial Cleanser Tablets 180 Count Cover #TOP 3
Polident 3 Minute Antibacterial Cleanser Tablets 180 Count
ftb score rating icon 9.5

Top 10 Denture Cleansers

#TOP 1

M3 Naturals Retainer Cleaner Tablets 4 Month Supply

Retainer Cleaner 120
M3 Naturals Retainer Cleaner Tablets 4 Month Supply Cover
M3 Naturals Retainer Cleaner Tablets Invisalign Cleaner FSA HSA Approved Remove Odors Discoloration Stains and Plaque 4 Month Supply Denture Cleansers Retainers Mouth Guards Denture Bath Mint

M3 Naturals Extra Strength Cleaning Tablets are designed to remove unwanted odor, discoloration, stains, plaque, and tartar from any oral dental appliance and denture bath. With 120 individually wrapped cleaning tablets, they are perfect for denture baths, retainers, aligners, Invisalign, mouth guards, night guards, snore guards, sport, TMJ devices, and all other removable dental appliances. Just drop one tablet into warm tap water along with your dental bath appliance and let it do the rest! Soaking daily in a denture bath is highly recommended to prevent food particle, cloudy film, and plaque buildup.

What We Like
Removes odor and stains
Dissolves quickly and fully
No chemical aftertaste
Keeps retainers clear and fresh
Long-lasting and cost-effective
What We Don't Like
Slightly higher price
#TOP 2

Retainer Brite Tablets

Retainer Brite Tablets Cover
Retainer Brite Retainer Cleaner Tablets for Ultrasonic Cleaners, Used for Cleaning Invisalign, Mouth Guard, Night Guard and More, 4 Month Supply, Made in USA,120 Tablets

Retainer Brite Dental Tablets are a convenient and effective solution for keeping your dental appliances clean and odor-free. Whether you use clear retainers, aligners, wire retainers, sports mouthguards, or nightguards, these tablets are designed to provide fast and easy cleaning. Simply soak your dental appliances in the solution daily for the best results. With 120 individually wrapped tablets in each package, you'll have a 4-month supply to keep your appliances clear, bright, and fresh. Say goodbye to the hassle of manual cleaning and enjoy the convenience of Retainer Brite Dental Tablets.

What We Like
Removes odor and buildup
Easy to use tablets
Individually wrapped for travel
Works with Invisalign and retainers
No aftertaste or residue
What We Don't Like
Poor packaging for some orders
Box may arrive dented
#TOP 3

Polident 3 Minute Antibacterial Cleanser Tablets 180 Count

Polident 3 Minute Antibacterial Cleanser Tablets 180 Count Cover
Polident 3 Minute Antibacterial Dental Appliance Cleanser Tablets, 90 Count (2 Pack)

The Polident Antibacterial Cleanser Tablets come in two boxes with 90 tablets each, giving you plenty of supply for your dental appliance care. This product features an improved formula that uses active power bubbles to reach and clean even the toughest spots on your dentures, retainers, or mouthguards. It kills 99.9% of odor-causing bacteria, helping to keep your appliance fresh and odor-free for longer. Designed specifically for various dental appliances including full and partial dentures, retainers, and aligners, these tablets provide a reliable and easy way to maintain your dental hygiene. Just soak, brush, rinse, and you're ready to go.

What We Like
Quick cleaning action
Kills 99.9% bacteria
No aftertaste or residue
Effective stain and odor removal
Good value pack
What We Don't Like
Generic brands less effective
#TOP 4

Efferdent Retainer Cleaning Tablets

10814832017054
Efferdent Retainer Cleaning Tablets Cover
Efferdent Retainer Cleaning Tablets, Denture Cleaning Tablets for Dental Appliances, Minty Fresh & Clean, 126 Count

Efferdent Cleaning Tablets are a convenient solution for keeping your dental appliances clean and fresh. Whether you have retainers, full-plate dentures, partials, aligners, or other dental appliances, these tablets are designed to effectively remove plaque build-up and kill odor-causing bacteria. With just a 3-minute cleaning, they can eliminate 99.99% of bacteria, leaving your appliances fresh and ready to use. The powerful oxi-action formula also helps to remove stubborn stains in hard-to-reach places, ensuring a thorough clean. Plus, the minty fresh flavor not only cleanses your dental appliances but also leaves them with a refreshing taste. With Efferdent Cleaning Tablets, you can maintain the cleanliness and hygiene of your dental appliances effortlessly.

What We Like
Effective cleaning power
Removes odor and stains
Easy and quick to use
Affordable price
Convenient for daily routine
What We Don't Like
Packaging tears awkwardly
#TOP 5

Zima Dental Pod Ultrasonic Cleaner

Zima Dental
KPD16
Arctic White
Zima Dental Pod Ultrasonic Cleaner Cover
Zima Dental Pod: Ultrasonic Retainer Cleaner. The Original Retainer Cleaner Machine, Aligner Cleaner, Nightguard Cleaner, Mouthguard Cleaner, Denture Cleaner. Ultrasonic Cleaner For Oral Dental Care

The Zima Dental Pod Cleaner uses advanced ultrasonic technology to effectively remove stains and plaque from your dental appliances without causing any damage. It’s incredibly easy to use: just fill it with water, place your appliance inside, and activate it for five minutes to achieve a sparkling clean. For those stubborn stains, adding a Zima Dental tablet enhances the cleaning process. Plus, with a risk-free 30-day money-back guarantee and a 12-month warranty, you can have peace of mind about your purchase.

What We Like
Easy to use
Thorough cleaning performance
Excellent customer service
Compact and sleek design
Good for multiple appliances
What We Don't Like
Occasional device malfunction
Water drainage minor issue
#TOP 6

Polident 3 Minute Antibacterial Cleanser Tablets 60 Count

Polident 3 Minute Antibacterial Cleanser Tablets 60 Count Cover
Polident 3 Minute Antibacterial Dental Appliance Cleanser Tablets, 60 Count

The Polident 3 Minute Cleanser offers a quick and effective way to clean your dental appliances. With 60 tablets included, you have plenty of supply to keep your retainers, dentures, or mouthguards fresh. Its improved formula features active power bubbles that reach even the toughest spots, ensuring a thorough clean. This cleanser also kills 99.9% of odor-causing bacteria, helping to keep your dental devices smelling fresh for longer. Designed for various dental appliances, it provides a deep, gentle clean that protects your items while making your daily routine easier.

What We Like
Quick cleaning time
Effective stain removal
No residue or odor
Fresh minty scent
Safe for dentures and retainers
What We Don't Like
Uncertain cleanliness for some users
#TOP 7

Efferdent Retainer Cleaning Tablets, 126 Tablets

01588
Multicolor
Efferdent Retainer Cleaning Tablets, 126 Tablets Cover
Efferdent Denture Cleaner Tablets – Dental Appliances, Aligners, Mouth Guard, and Retainer Cleaner Tablets, Complete Clean, 126 Count

Use Efferdent Retainer Cleaning Tablets daily to clean retainers, full-plate dentures, partials, aligners, and other dental appliances. The Complete Clean formula kills 99.99% of odor-causing bacteria in 3 minutes while being gentle and non-abrasive. The powerful oxi-action of the tablets removes stubborn stains in hard-to-reach places and fights plaque build-up. Efferdent Retainer Cleaning Tablets leave dental appliances fresh and ready-to-use.

What We Like
Easy daily cleaning process
Prevents odor and buildup
No strong aftertaste or scent
Affordable and budget-friendly
Works on multiple appliances
What We Don't Like
May not remove all odors
Less effective in cold water
#TOP 8

Polident Overnight Whitening Dental Appliance Cleanser Tablets 90 Count 2 Pack

Polident Overnight Whitening Dental Appliance Cleanser Tablets 90 Count 2 Pack Cover
Polident Overnight Whitening Antibacterial Dental Appliance Cleanser Tablets, 90 Count (2 Pack)

The Polident Whitening Cleanser Tablets offer a powerful cleaning solution for your dental appliances. With an improved formula featuring active power bubbles, these tablets reach even the most difficult spots, ensuring a thorough clean. You can trust these tablets to eliminate 99.9% of odor-causing bacteria, which helps keep your retainer or denture fresh and odor-free for longer periods. Plus, the cleanser removes stains effectively without the need for brushing, saving you time and effort while maintaining the appearance of your dental appliance. The Polident Whitening Cleanser Tablets are an easy and efficient way to keep your dental devices clean and fresh every day.

What We Like
Effective cleaning performance
Easy to use
Antibacterial protection
Subtle whitening effect
Good value multi-pack
What We Don't Like
Slightly higher price
Whitening effect is mild
#TOP 9

Jepwe Ultrasonic Retainer Cleaner with UV-C

jepwe
GT03
White
Jepwe Ultrasonic Retainer Cleaner with UV-C Cover
Jepwe Ultrasonic Retainer Cleaner with UV-C, 45kHz Rechargeable Dental Cleaning Machine 4000mAh, 200ML for Denture, Mouth Guard, Night Guard, Aligner, 3 Modes & 6 Cleaning Tablets

The Jepwe Ultrasonic Retainer Cleaner offers powerful 45kHz ultrasonic waves that create tiny bubbles to deeply clean your dental appliances, removing plaque, stains, and food debris without causing any damage. It combines this ultrasonic action with built-in UV-C light, which helps eliminate odors and harmful germs without needing harsh chemicals, keeping your retainers and aligners fresh and hygienic. You can choose from three cleaning modes to fit your schedule, whether you need a quick daily clean, a deeper stain removal, or just a refreshing UV-C treatment. Plus, its compact size with a 200ml tank makes it easy to use at home or on the go, fitting various dental devices comfortably.

What We Like
Superior buildup removal
Gentle on retainers
Easy nightly use
No scratching on clear trays
Thorough cleaning performance
#TOP 10

Retainer Brite Cleaning Tablets 96 Count

RB-92
Basic
Retainer Brite Cleaning Tablets 96 Count Cover
Retainer Brite Tablets for Cleaner Retainers and Dental Appliances - 96 Count

Retainer Brite Cleaning Tablets are designed to keep your dental appliances fresh and spotless. If you wear clear retainers, aligners, wire retainers, sports mouthguards, or nightguards, these tablets help remove buildup and odors, making your appliances feel clean and comfortable daily. They are simple to use—just soak your items in the solution, and the fast-acting formula works to dissolve cloudy films and plaque, which can affect both hygiene and appearance. This product is especially made for removable dental devices, giving you an easy way to maintain your oral gear without hassle.

What We Like
Easy to use
Keeps retainers clear
Removes stains and odor
Effective for various appliances
Reasonable price
What We Don't Like
Not suitable for soldered metal
Results may vary by usage
Buying Guide Image

The Complete Guide to Buying Denture Cleansers

Introduction to Denture Cleansers

If you wear dentures, then you know how important it is to keep them clean and well-maintained. Not only do clean dentures look and smell better, but they can also help to prevent infections and other dental problems. One way to keep your dentures clean is by using a denture cleanser. In this article, we will discuss how to choose the best denture cleanser for your needs.

Types of Denture Cleansers

There are several types of denture cleansers available on the market, each with its own unique set of benefits and drawbacks. Some of the most common types of denture cleansers include:

  • Powdered denture cleansers: Powdered denture cleansers are typically mixed with water to create a foamy solution that can be used to clean dentures. They are often more affordable than other types of denture cleansers, but they can be messy and may not be as effective at removing tough stains.

  • Liquid denture cleansers: Liquid denture cleansers are pre-mixed solutions that are easy to use and typically come in convenient squeeze bottles. They are generally more effective at removing tough stains and are less messy than powdered denture cleansers, but they can be more expensive.

  • Tablets: Denture cleaning tablets are another popular option. These tablets are typically dropped into a cup of water, where they dissolve and create a cleaning solution. They are easy to use and are generally more effective at removing tough stains than powdered or liquid denture cleansers. However, they can be more expensive and may not be as effective at removing plaque and bacteria.

Considerations When Choosing a Denture Cleanser

When choosing a denture cleanser, there are a few key factors to consider. These include:

  • Effectiveness: The most important factor to consider when choosing a denture cleanser is its effectiveness at cleaning and disinfecting your dentures. Look for cleansers that are specifically designed to remove tough stains, plaque, and bacteria.

  • Convenience: Another important factor to consider is the convenience of the denture cleanser. Powdered and liquid denture cleansers can be messy and require you to mix and measure the solution, while tablets are easy to use but may be more expensive. Consider your personal preferences and lifestyle when choosing a denture cleanser.

  • Cost: Denture cleansers can vary widely in price, so it's important to consider your budget when choosing one. Powdered denture cleansers are typically the most affordable option, while tablets are often the most expensive.

  • Compatibility: Some denture cleansers may not be suitable for certain types of dentures, such as those made of acrylic or those with metal attachments. Be sure to check the label of the denture cleanser to ensure that it is compatible with your dentures.

Conclusion

Choosing the right denture cleanser is an important decision that can help to keep your dentures clean and well-maintained. Consider the different types of denture cleansers, their effectiveness, convenience, cost, and compatibility when making your decision. By taking the time to find the right denture cleanser for your needs, you can help to ensure that your dentures are clean and healthy for years to come.

Frequently Asked Questions (FAQs)

1. How can I get my dentures really clean?

To get your dentures really clean, brush them first to remove any food particles. Use a non-abrasive denture cleaner instead of toothpaste. Always clean your dentures over a bowl of water or a folded towel in case you accidentally drop them.

2. What can I soak my dentures in to remove plaque?

You can prepare a solution of two teaspoons of baking soda mixed with one cup of warm water to soak your dentures overnight. The enzymatic properties of baking soda will help remove plaque. Thoroughly brush your dentures the next morning to clean any remaining plaque deposits.

3. Can you leave dentures in Efferdent overnight?

Yes, Efferdent overnight denture cleanser can be safely used to soak dentures overnight. The product has been recognized by the ADA Council on Scientific Affairs for its safety and efficacy in cleaning removable prostheses when used as directed.

4. Can I soak my dentures in hydrogen peroxide overnight?

No, household hydrogen peroxide should not be used to soak dentures. It can potentially harm your dentures and cause warping or shape changes. Stick to recommended denture cleansers for soaking your dentures.

5. Can I soak my dentures in Listerine overnight?

Yes, it is safe to soak your dentures in Listerine overnight. Listerine will not damage your dentures. Remember to keep your mouth and dentures clean for overall oral hygiene.

6. How do you remove built-up plaque from dentures?

To remove built-up plaque from dentures, soak them in a baking soda solution for 30 minutes. Mix a tablespoon of baking soda with a cup of warm water. After soaking, brush your dentures with a toothbrush to remove any remaining plaque.

7. How long do you soak dentures in cleanser?

The soaking time for dentures in cleanser varies. It can range from 3 to 5 minutes up to an hour. Most dentures do not need to soak overnight. After soaking, use a soft brush to clean the denture with the cleaning solution. Rinse the denture well under cool running water.

Editor's Notes

During our denture cleanser research, we found 24 denture cleanser products and shortlisted 10 quality products. We collected and analyzed 594,562 customer reviews through our big data system to write the denture cleansers list. We found that most customers choose denture cleansers with an average price of $28.95.

The denture cleansers are available for purchase. We have researched hundreds of brands and picked the top brands of denture cleansers, including Retainer Brite, Polident, efferdent, Zima Dental, jepwe. The seller of top 1 product has received honest feedback from 1,251 consumers with an average rating of 4.9.

Written by
Elisa Drew Avatar

Elisa Drew is a really professional copywriter specializing in baby products with five years of experience working as a pediatrician once. She has published a series of baby books purchased by over thirty thousand people in the United States.