Best Hypoallergenic Crib Mattresses of 2025

The Serta Perfect Slumber Dual Sided Crib and Toddler Mattress is an excellent choice for parents seeking a non-toxic, hypoallergenic sleeping option for their child. Made from premium, sustainably sourced fiber core, the mattress is GREENGUARD Gold certified and meets or exceeds all flammability, lead, phthalate and CPSIA testing. The waterproof vinyl cover is easy to clean and both sides of the mattress feature a waterproof cover, making it easy to flip when it's time for your baby to move to a toddler bed. With a 7-year warranty, this lightweight mattress is made in the USA and fits standard cribs and toddler beds.

The Sealy Flex Cool Crib Mattress is a top-rated safety mattress that has been certified by GREENGUARD GOLD, ASTM, and CPSIA. It features a 2-stage firmness design that offers a firmer side for infants and a cozier side for toddlers. The breathable cotton cover and waterproof barrier make cleaning easy, while the 204 durable steel coils provide premium posture support for your baby. Made in the USA, this mattress fits all standard-size cribs and toddler beds and comes with a lifetime warranty. With its dual firmness, safety certifications, and premium support features, the Sealy Flex Cool Crib Mattress is an excellent choice for your baby's sleeping needs.

The Organic Cotton Dual-Sided Crib Mattress is a 2-stage premium memory foam CertiPUR-US hypoallergenic baby mattress with firm support for infants and cooling gel for toddlers. It is perfect for providing a safe and comfortable sleeping surface for your baby. The infant side is made of high-density foam to provide optimal firmness, thickness, flat surface, and stable edges while the toddler side has a breathable, cooling gel foam material that supports healthy posture and enhances relaxation. The organic cotton cover is easy to clean and hypoallergenic. All materials used are CertiPUR-US certified and laboratory tested for maximum safety assurance.

The Sealy Airy Night Crib Mattress is a premium and safe choice for your baby's nursery. It is GREENGUARD GOLD Air Quality Certified, ensuring a healthier indoor environment by limiting the presence of harmful chemicals and VOCs. The 2-Stage mattress features a breathable mesh and antibacterial surfaces, providing comfort and protection for your little one. The waterproof cover with rayon from bamboo silky mesh allows for breathability on the infant side, while the hospital-grade antibacterial surface on the toddler side helps prevent bacterial growth. This mattress also meets ASTM safety standards, reducing the risk of suffocation. The Sealy Airy Night Crib Mattress is made with sustainable materials and offers a lifetime warranty, making it a trusted and reliable choice for your baby's crib.

The Sealy Posturepedic Grace 2-Stage Waterproof Baby Crib and Toddler Mattress features Posturepedic Advanced Zone Support that offers targeted support and comfort as your child grows. The hybrid design includes 204 premium steel innerspring and family-friendly soybean memory foam for a lifetime of support. The mattress comes with a breathable cotton waterproof cover, earth-friendly cushioning, and a 2-stage design that is safety tested for infants and toddlers.

The Sealy Perfect Rest Waterproof Baby Crib and Toddler Mattress is an extra firm mattress made with 150 premium coils in the USA. The waterproof surface is easy to clean and the airy cushioning provides comfort for infants and toddlers. It is non-toxic and GREENGUARD GOLD certified, passing regulations for over 80 chemicals. Additionally, it fits into a standard crib and toddler bed with excellent sheet fit.

The iMMDOKIN Crib Mattress offers a safe and comfortable sleeping environment for your baby. With its CertiPUR-US certified foam and OEKO-TEX STANDARD 100 cover, you can feel confident about your child's safety. The allergen-resistant design features a waterproof cover that protects against spills and allergens, keeping your baby's skin safe. Its dual-sided design caters to your child's growth, providing a firmer side for infants and a softer side for toddlers. Plus, the easy-to-clean cover allows you to quickly wipe away stains or toss it in the washing machine for a thorough clean, saving you time and effort.

This non-toxic crib mattress features no seams, providing a tight fit to standard size cribs and toddler beds. Made of soft and strong high grade memory foam, it offers good support and stability, reducing the risk of physical injury and suffocation. The surface is made of breathable and odorless high-grade velvet. Convenient to use, it can quickly recover and is ready for normal use in 3-5 days. Customer support is available.

The Newton Baby Crib Mattress is a 2-stage crib mattress designed to support your growing baby, with an innovative Breathe-Thru Technology that allows your baby to breathe right through, reducing the risk of suffocation and CO2 rebreathing. The mattress is also 100% washable from cover to core, making it easy to clean and maintain. It is made without foam, glue, latex or springs, and is the only 100% recyclable crib mattress. The right level of comfort, support and air circulation means your baby will sleep better on a Newton. The mattress is GREENGUARD Gold certified and recommended by pediatricians for your baby's health, safety and development.

The Nature Bee Crib Mattress is designed with your baby's safety in mind. Its zero-toxin promise means no harmful materials like foam or fiberglass are included, creating a healthier sleep space. The mattress is fully breathable, allowing air to flow freely from the core to the surface, which helps regulate your baby's temperature. With a honeycomb fiber core, it enhances airflow for a more comfortable sleep. Additionally, the organic cotton surface is hypoallergenic, making it gentle on your baby's sensitive skin. This combination ensures a safe and cozy environment for your little one.