Best Creams Cortisone Treatments of 2026

Bonnie Salem Avatar
Bonnie Salem
Last Updated: Jan 16, 2026

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Creams Cortisone Treatments are a range of topical creams that are designed to provide relief from skin irritations and inflammations. These creams contain cortisone, a steroid hormone that helps to reduce inflammation and redness in the affected area. Creams Cortisone Treatments are available in various strengths, from mild to extra-strength, and are suitable for use on a variety of skin conditions, including eczema, psoriasis, and insect bites. The creams are easy to apply and are quickly absorbed into the skin, providing fast and effective relief from symptoms. With their proven effectiveness and ease of use, Creams Cortisone Treatments are a popular choice for those seeking relief from skin irritations.

At a Glance: Our Top Picks

Cortizone 10 Maximum Strength Cream Cover #TOP 1
Cortizone 10 Maximum Strength Cream
ftb score rating icon 9.9
Amazon Basic Care Anti-Itch Cream Plus 10 Moisturizers Cover #TOP 2
Amazon Basic Care Anti-Itch Cream Plus 10 Moisturizers
ftb score rating icon 9.8
Cortizone-10 Maximum Strength Anti-Itch Cream Cover #TOP 3
Cortizone-10 Maximum Strength Anti-Itch Cream
ftb score rating icon 9.6

Top 10 Creams Cortisone Treatments

#TOP 1

Cortizone 10 Maximum Strength Cream

842805
White
2 Ounce (Pack of 1)
Cortizone 10 Maximum Strength Cream Cover
Cortizone-10 Maximum Strength Intensive Healing Itch Relief Cream, 1% Hydrocortisone, Fast-Acting, Anti-Itch Cream for Bug Bites, Rash, Eczema, Psoriasis, Poison Ivy, Oak, Sumac & More, 2 oz

Cortizone 10 Anti-Itch Cream provides quick relief from itchiness caused by minor skin irritations such as dryness and chafing. With its powerful 1% hydrocortisone formula, you can expect noticeable results in under 10 minutes. This cream also includes seven moisturizers and essential vitamins A, C, and E, ensuring that your skin stays nourished and hydrated. Enjoy the convenience of 24-hour moisture without any fragrances or dyes, making it gentle for all skin types. Experience effective itch relief without needing a prescription.

What We Like
Fast itch relief
Soothes sensitive skin
No sticky residue
Good value
Moisturizing effect
#TOP 2

Amazon Basic Care Anti-Itch Cream Plus 10 Moisturizers

Amazon Basic Care
S0056AN
2 Ounce (Pack of 1)
Amazon Basic Care Anti-Itch Cream Plus 10 Moisturizers Cover
Amazon Basic Care Maximum Strength Hydrocortisone 1 Percent Anti-Itch Cream Plus 10 Moisturizers, 2 ounce (Pack of 1)

Amazon Basic Care Maximum Strength Hydrocortisone 1 Percent Anti-Itch Cream Plus 10 Moisturizers is a fast-acting cream that relieves itching and rashes associated with poison ivy, oak, and sumac, as well as insect bites, eczema, and more. It contains vitamins A, D, and E, aloe, and the active ingredient hydrocortisone 1 percent, which is the number one doctor-recommended anti-itch active ingredient. This cream is ultra-moisturizing and enriched with 10 soothing moisturizers that provide relief for skin redness, irritation, rashes, and inflammation, making it an essential item for your first aid kit and medicine cabinet.

What We Like
Fast itch relief
Moisturizing formula
Non-greasy texture
Budget-friendly price
Versatile use
#TOP 3

Cortizone-10 Maximum Strength Anti-Itch Cream

SA00215
Multicolor
2 Ounce (Pack of 1)
Cortizone-10 Maximum Strength Anti-Itch Cream Cover
Cortizone-10 Maximum Strength Soothing Aloe Itch Relief Cream, 1% Hydrocortisone, Fast-Acting, Anti-Itch Cream for Bug Bites, Rash, Eczema, Psoriasis, Poison Ivy, Oak, Sumac & More, 2 oz

Cortizone-10 Anti-Itch Cream is a maximum-strength cream that provides fast relief for itch and inflammation associated with eczema, psoriasis, and poison oak, ivy, and sumac. With its 1% hydrocortisone formula, this cream offers the highest level of itch relief without a prescription. In just under 10 minutes, it effectively relieves itch and provides long-lasting relief that lasts for hours. The cream is also fragrance-free and dye-free, making it suitable for those with sensitive skin. Cortizone-10 Anti-Itch Cream is the #1 Doctor-Recommended OTC Anti-Itch Brand, according to a 2021 IQVIA Study. Experience the soothing and fast-acting relief of Cortizone-10 Anti-Itch Cream today!

What We Like
Fast itch relief
Soothing and cooling effect
Non-greasy, absorbs quickly
No scent or odor
Good value for money
#TOP 4

Globe Hydrocortisone Cream

Globe
8899-FBA-4
1 Ounce (Pack of 4)
Globe Hydrocortisone Cream Cover
Globe (4 Pack) Hydrocortisone Maximum Strength Anti-Itch Cream 1% w/Aloe, Intensive Formula for Redness, Rash, Bug & Mosquito Bites, Eczema, Hemorrhoids, Sensitive Skin, Instant Itch Relief,1 oz Tube

Globe Hydrocortisone Cream is a fast and effective solution for skin irritation and rashes. With the power of hydrocortisone 1% and the soothing properties of aloe vera, it provides relief for inflammation, redness, and itching caused by insect bites, poison ivy, oak, and sumac. It is also beneficial for conditions like eczema, psoriasis, and seborrheic dermatitis. This pharmacist-recommended cream is safe for adults and children 12 years and older. It can be used as a home remedy or included in your first aid kit for immediate relief. Globe Hydrocortisone Cream comes in a pack of 4 tubes, offering amazing value compared to leading brands.

What We Like
Fast itch relief
Affordable price
Works as well as name brands
Helps eczema and cracked skin
Non-greasy texture
#TOP 5

Medpride Hydrocortisone 1% Anti Itch Cream

Medpride Hydrocortisone 1% Anti Itch Cream Cover
MED Pride 1% Hydrocortisone Cream Bulk 16 Oz Maximum Strength Itch Relief for Eczema, Dermatitis, Rashes, Mosquito Bites

Medpride Hydrocortisone 1% Anti Itch Cream provides instant relief against itch, rash, and pain caused by skin conditions such as eczema, dermatitis, skin rashes, allergic reactions, and hyper-sensitive skin. Suitable for all skin types, including children, it has a fast-acting formula that delivers instant results without causing any discomfort. Its maximum strength formula contains 1% hydrocortisone, which combats redness, swelling, and inflammation, making it a proven effective solution for an array of skin conditions. You can apply the cream up to 3 times a day to the affected area and soon all the pain and discomfort will be gone.

What We Like
Relieves skin itchiness quickly
Large, long-lasting container
Affordable price
Smooth, easy application
#TOP 6

Cortizone 10 Maximum Strength Ointment

Multicolor
2 Ounce (Pack of 1)
Cortizone 10 Maximum Strength Ointment Cover
Cortizone-10 Maximum Strength Water Resistant Itch Relief Ointment, 1% Hydrocortisone, Fast-Acting, Anti-Itch Cream for Bug Bites, Rash, Eczema, Psoriasis, Poison Ivy, Oak, Sumac & More, 2 oz

Cortizone 10 Anti-Itch Ointment is designed to provide quick relief from itching and inflammation caused by conditions like eczema, psoriasis, and reactions to poison ivy, oak, or sumac. This ointment contains 1% hydrocortisone, offering maximum-strength relief without needing a prescription. Its water-resistant formula, enriched with petrolatum, helps create a protective barrier on your skin while locking in moisture. You can expect relief in under 10 minutes, with effects that last for hours, making it a convenient choice for those seeking effective itch relief.

What We Like
Fast itch relief
Long-lasting waterproof formula
Easy application
No unpleasant odor
Repairs damaged skin
#TOP 7

Cortizone-10 Ultra Soothing Anti-Itch Cream

Multicolor
2 Ounce (Pack of 1)
Cortizone-10 Ultra Soothing Anti-Itch Cream Cover
Cortizone-10 Maximum Strength Ultra Soothing Itch Relief Cream, 1% Hydrocortisone, Fast-Acting, Anti-Itch Cream for Bug Bites, Rash, Eczema, Psoriasis, Poison Ivy, Oak, Sumac & More, 2 oz

Cortizone-10 Ultra Soothing Anti-Itch Cream, also known as Cortizone-10 Itch Cream, is a maximum strength cream that provides fast relief for itch and inflammation associated with eczema, psoriasis, and poison oak, ivy, and sumac. With its 1% hydrocortisone formula, this cream offers maximum-strength itch relief without a prescription. It contains 10 moisturizers and aloe, which help to soften and soothe the skin. The cream is non-irritating, fragrance-free, and dye-free, making it suitable for sensitive skin. Cortizone-10 Ultra Soothing Anti-Itch Cream provides quick relief in under 10 minutes and lasts for hours, allowing you to go about your day without the discomfort of itching and inflammation.

What We Like
Itch relief
Easy application
Reduces irritation and redness
Speeds healing
Effective for burns and cuts
#TOP 8

Globe Hydrocortisone Maximum Strength Cream 1% w/Aloe, 16 oz

Globe
8897-FBA
White Cream
16 Ounce
Globe Hydrocortisone Maximum Strength Cream 1% w/Aloe, 16 oz Cover
Globe Hydrocortisone Maximum Strength Cream 1% w/Aloe, 16 oz, Anti-Itch Cream for Redness, Swelling, Itching, Rash, Bug/Mosquito Bites, Eczema, Hemorrhoids & More, 16 oz Jar

Globe Hydrocortisone Maximum Strength Cream combines hydrocortisone 1% with aloe vera, providing fast and effective relief for skin irritation, rashes, inflammation, redness, insect bites, poison ivy, oak, and sumac. It can also ease the symptoms of eczema, psoriasis, and other forms of dermatitis. This safe and effective home remedy is recommended by pharmacists and comes in a 16 oz jar for the price of 2 oz of the leading name brand.

What We Like
Great for sensitive dry skin
Cost-effective compared to smaller sizes
Good quality and quick shipping
Easy to use and spreads well
#TOP 9

MED Pride Hydrocortisone Cream 1% Bulk Pack

1 Ounce (Pack of 4)
MED Pride Hydrocortisone Cream 1% Bulk Pack Cover
MED Pride Hydro Cortisone (Hydrocortisone) Cream 1% OTC Bulk Pack of 4 X 1 Oz Anti-Itch Ointment for Rash, Eczema, Bug Bites

The MED Pride Hydrocortisone Cream is a reliable solution for soothing itchy and irritated skin. It contains 1% hydrocortisone, which helps reduce redness, swelling, and itchiness caused by rashes, eczema, bug bites, and more. You can easily apply it to affected areas for quick relief from mosquito bites and other skin discomforts. This cream is also versatile, making it useful for various skin problems, so it’s a handy addition to your first aid supplies. With MED Pride Hydrocortisone Cream, you get fast and effective relief without needing a prescription.

What We Like
Effective itch relief
Reduces redness and swelling
Easy topical application
Versatile for multiple skin issues
#TOP 10

CareAll Hydrocortisone 1% Anti-Itch Cream 4-Pack

HYD1-4PK
1 Ounce (Pack of 4)
CareAll Hydrocortisone 1% Anti-Itch Cream 4-Pack Cover
CareAll Hydrocortisone 1%, 1oz Tube (Pack of 4), Maximum Strength Anti-Itch Cream, Relief from Itching and Redness from Bug Bites, Eczema, Psoriasis, Poison Ivy, Oak and Sumac

The CareAll Hydrocortisone Cream offers strong relief for itching caused by various skin irritations. Its 1% hydrocortisone formula helps calm minor rashes and inflammation, making it easier for you to feel comfortable. This cream is designed to provide maximum relief from itchiness due to eczema, psoriasis, poison ivy, insect bites, and more, so you can get back to your day without distraction. Each 1oz tube comes with a tamper-evident seal, ensuring the product is safe and secure before you use it. This thoughtful packaging gives you peace of mind about the cream’s quality and freshness.

What We Like
1% Hydrocortisone active ingredient
Effective itch and inflammation relief
Maximum strength formula
Tamper-evident safety seal
Buying Guide Image

Frequently Asked Questions (FAQs)

1. What is cortisone cream best for?

This medication is used to treat a variety of skin conditions (such as insect bites, poison oak/ivy, eczema, dermatitis, allergies, rash, itching of the outer female genitals, anal itching). Hydrocortisone reduces the swelling, itching, and redness that can occur in these types of conditions.

2. Can I buy cortisone cream over the counter?

Mild corticosteroids, such as clobetasone, hydrocortisone skin cream and hydrocortisone for piles and itchy bottom, can often be bought over the counter from pharmacies. Stronger types, such as beclometasone, betamethasone, clobetasol, fluticasone and mometasone, are only available on prescription.

3. What is better cortisone cream or ointment?

Creams are better for skin that is moist and weepy. Ointments are thicker and greasier, and are better for dry or flaky areas of skin. Most people need to use hydrocortisone cream or ointment once or twice a day.

Editor's Notes

During our creams cortisone treatment research, we found 24 creams cortisone treatment products and shortlisted 10 quality products. We collected and analyzed 303,016 customer reviews through our big data system to write the creams cortisone treatments list. We found that most customers choose creams cortisone treatments with an average price of $7.33.

The creams cortisone treatments are available for purchase. We have researched hundreds of brands and picked the top brands of creams cortisone treatments, including Cortizone 10, Globe, MED PRIDE, CareAll. The seller of top 1 product has received honest feedback from 384 consumers with an average rating of 4.7.

Written by
Bonnie Salem Avatar

Bonnie Salem is a stay-at-home mother with two-year-old twins and has spent almost half of her life surrounded by baby products. As a mother and a professional copywriter, she has an insightful and unique eye for researching products suitable for infants. Bonnie Salem is an expert in health and nutrition who lives with her family in New Jersey. She has over 15 years of working experience in an institute of medicine after graduating from the University of Toronto. She is highly interested in personal health and wellness.