Best Creams Cortisone Treatments of 2025

Bonnie Salem Avatar
Bonnie Salem
Last Updated: Jan 4, 2025

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Creams Cortisone Treatments are a range of topical creams that are designed to provide relief from skin irritations and inflammations. These creams contain cortisone, a steroid hormone that helps to reduce inflammation and redness in the affected area. Creams Cortisone Treatments are available in various strengths, from mild to extra-strength, and are suitable for use on a variety of skin conditions, including eczema, psoriasis, and insect bites. The creams are easy to apply and are quickly absorbed into the skin, providing fast and effective relief from symptoms. With their proven effectiveness and ease of use, Creams Cortisone Treatments are a popular choice for those seeking relief from skin irritations.

At a Glance: Our Top Picks

Cortizone-10 Maximum Strength Anti-Itch Cream Cover #TOP 1
Cortizone-10 Maximum Strength Anti-Itch Cream
ftb score rating icon 9.9
Cortizone 10 Maximum Strength Cream Cover #TOP 2
Cortizone 10 Maximum Strength Cream
ftb score rating icon 9.8
Cortizone-10 Ultra Soothing Anti-Itch Cream Cover #TOP 3
Cortizone-10 Ultra Soothing Anti-Itch Cream
ftb score rating icon 9.6

Top 10 Creams Cortisone Treatments

#TOP 1

Cortizone-10 Maximum Strength Anti-Itch Cream

SA00215
Multicolor
2 Ounce (Pack of 1)
Cortizone-10 Maximum Strength Anti-Itch Cream Cover
Cortizone 10 Maximum Strength Anti-Itch Cream with Soothing Aloe, 1% Hydrocortisone Creme, 2 oz.

Cortizone-10 Anti-Itch Cream is a maximum-strength cream that provides fast relief for itch and inflammation associated with eczema, psoriasis, and poison oak, ivy, and sumac. With its 1% hydrocortisone formula, this cream offers the highest level of itch relief without a prescription. In just under 10 minutes, it effectively relieves itch and provides long-lasting relief that lasts for hours. The cream is also fragrance-free and dye-free, making it suitable for those with sensitive skin. Cortizone-10 Anti-Itch Cream is the #1 Doctor-Recommended OTC Anti-Itch Brand, according to a 2021 IQVIA Study. Experience the soothing and fast-acting relief of Cortizone-10 Anti-Itch Cream today!

What We Like
Fast relief for itch and inflammation
Lasts for hours
Doctor-Recommended
#TOP 2

Cortizone 10 Maximum Strength Cream

842805
White
2 Ounce (Pack of 1)
Cortizone 10 Maximum Strength Cream Cover
Cortizone 10 Maximum Strength Intensive Moisture Anti-Itch Cream, 1% Hydrocortisone, 2 oz.

Cortizone 10 Anti-Itch Cream provides quick relief from itchiness caused by minor skin irritations such as dryness and chafing. With its powerful 1% hydrocortisone formula, you can expect noticeable results in under 10 minutes. This cream also includes seven moisturizers and essential vitamins A, C, and E, ensuring that your skin stays nourished and hydrated. Enjoy the convenience of 24-hour moisture without any fragrances or dyes, making it gentle for all skin types. Experience effective itch relief without needing a prescription.

What We Like
Fast itch relief
Long-lasting moisture
Gentle on skin
Contains vitamins
#TOP 3

Cortizone-10 Ultra Soothing Anti-Itch Cream

Multicolor
2 Ounce (Pack of 1)
Cortizone-10 Ultra Soothing Anti-Itch Cream Cover
Cortizone 10 Maximum Strength Ultra Soothing Anti-Itch Cream, 1% Hydrocortisone Creme, 2 oz.

Cortizone-10 Ultra Soothing Anti-Itch Cream, also known as Cortizone-10 Itch Cream, is a maximum strength cream that provides fast relief for itch and inflammation associated with eczema, psoriasis, and poison oak, ivy, and sumac. With its 1% hydrocortisone formula, this cream offers maximum-strength itch relief without a prescription. It contains 10 moisturizers and aloe, which help to soften and soothe the skin. The cream is non-irritating, fragrance-free, and dye-free, making it suitable for sensitive skin. Cortizone-10 Ultra Soothing Anti-Itch Cream provides quick relief in under 10 minutes and lasts for hours, allowing you to go about your day without the discomfort of itching and inflammation.

What We Like
Fast relief
Maximum-strength itch relief
Long-lasting effect
#TOP 4

Globe Hydrocortisone Cream

Globe
8899-FBA-4
1 Ounce (Pack of 4)
Globe Hydrocortisone Cream Cover
Globe (4 Pack) Hydrocortisone Maximum Strength Anti-Itch Cream 1% w/Aloe, Intensive Formula for Redness, Rash, Bug & Mosquito Bites, Eczema, Hemorrhoids, Sensitive Skin, Instant Itch Relief,1 oz Tube

Globe Hydrocortisone Cream is a fast and effective solution for skin irritation and rashes. With the power of hydrocortisone 1% and the soothing properties of aloe vera, it provides relief for inflammation, redness, and itching caused by insect bites, poison ivy, oak, and sumac. It is also beneficial for conditions like eczema, psoriasis, and seborrheic dermatitis. This pharmacist-recommended cream is safe for adults and children 12 years and older. It can be used as a home remedy or included in your first aid kit for immediate relief. Globe Hydrocortisone Cream comes in a pack of 4 tubes, offering amazing value compared to leading brands.

What We Like
Fast and effective relief
Combines hydrocortisone and aloe vera
Safe for adults and children
#TOP 5

Globe Hydrocortisone Maximum Strength Cream 1% w/Aloe, 16 oz

Globe
8897-FBA
White Cream
16 Ounce
Globe Hydrocortisone Maximum Strength Cream 1% w/Aloe, 16 oz Cover
Globe Hydrocortisone Maximum Strength Cream 1% w/Aloe, 16 oz, Anti-Itch Cream for Redness, Swelling, Itching, Rash, Bug/Mosquito Bites, Eczema, Hemorrhoids & More, 16 oz Jar

Globe Hydrocortisone Maximum Strength Cream combines hydrocortisone 1% with aloe vera, providing fast and effective relief for skin irritation, rashes, inflammation, redness, insect bites, poison ivy, oak, and sumac. It can also ease the symptoms of eczema, psoriasis, and other forms of dermatitis. This safe and effective home remedy is recommended by pharmacists and comes in a 16 oz jar for the price of 2 oz of the leading name brand.

What We Like
Fast and effective relief for various skin conditions
Combines hydrocortisone 1% with aloe vera for added healing properties
Recommended by pharmacists
Large 16 oz jar provides excellent value for money
#TOP 6

Medpride Hydrocortisone 1% Anti Itch Cream

Medpride Hydrocortisone 1% Anti Itch Cream Cover
Medpride 1% Hydrocortisone Cream - Maximum Strength Itch Relief for Mosquito Bites, Eczema, Dermatitis - 16 oz

Medpride Hydrocortisone 1% Anti Itch Cream provides instant relief against itch, rash, and pain caused by skin conditions such as eczema, dermatitis, skin rashes, allergic reactions, and hyper-sensitive skin. Suitable for all skin types, including children, it has a fast-acting formula that delivers instant results without causing any discomfort. Its maximum strength formula contains 1% hydrocortisone, which combats redness, swelling, and inflammation, making it a proven effective solution for an array of skin conditions. You can apply the cream up to 3 times a day to the affected area and soon all the pain and discomfort will be gone.

What We Like
Instant relief against itch, rash, and pain
Fast-acting formula for instant results
Suitable for all skin types, including children
#TOP 7

Cortizone 10 Maximum Strength Anti-Itch Cream

SA00210
Multicolor
1 Ounce (Pack of 1)
Cortizone 10 Maximum Strength Anti-Itch Cream Cover
Cortizone 10 Maximum Strength Anti-Itch Cream with Soothing Aloe, 1% Hydrocortisone Creme, 1 oz.

Cortizone 10 Anti-Itch Cream offers quick relief from itching and inflammation caused by conditions like eczema, psoriasis, and reactions to poison ivy, oak, and sumac. Formulated with 1% hydrocortisone, it provides maximum-strength relief without needing a prescription. The inclusion of soothing aloe vera helps calm your skin while the hydrocortisone tackles the itch. You can expect relief in under 10 minutes, making it a convenient solution for those sudden itch flare-ups. This cream is also fragrance-free and dye-free, ensuring it's gentle on your skin.

What We Like
Fast relief from itch
Soothes with aloe vera
Maximum strength without prescription
Fragrance and dye free
#TOP 8

Globe Hydrocortisone Cream for Skin Irritation and Rashes

8899-SL
1 Ounce (Pack of 3)
Globe Hydrocortisone Cream for Skin Irritation and Rashes Cover
(3 Pack) Globe Hydrocortisone Maximum Strength Cream 1% w/Aloe, Anti-Itch Cream for Redness, Swelling, Itching, Rash, Bug/Mosquito Bites, Eczema, Hemorrhoids & More

Globe Hydrocortisone Maximum Strength Cream is a fast and effective relief for skin irritation, rashes, inflammation, insect bites, poison ivy, oak, and sumac. It contains hydrocortisone 1% and aloe vera that soothes, moisturizes and heals the skin. Recommended by pharmacists, this cream is safe and useful for adults and children 12 years and older. It can ease the symptoms of eczema, psoriasis, seborrheic dermatitis, and other dermatitis. With three tubes of 1 oz each, it is an amazing deal.

What We Like
Fast and effective relief for skin irritation and rashes
Contains hydrocortisone 1% and aloe vera to soothe, moisturize, and heal the skin
Recommended by pharmacists for treating eczema, psoriasis, and other dermatitis
Useful for adults and children 12 years and older
An amazing deal with three tubes of 1 oz each
#TOP 9

CareAll (3 Pack) 1% Hydrocortisone Cream

HYD1-3PK
1 Ounce (Pack of 3)
CareAll (3 Pack) 1% Hydrocortisone Cream Cover
CareAll Hydrocortisone 1%, 1oz Tube (Pack of 3), Maximum Strength Anti-Itch Cream, Relief from Itching and Redness from Bug Bites, Eczema, Psoriasis, Poison Ivy, Oak and Sumac

This 3 pack of CareAll cream contains 1% hydrocortisone, which provides maximum strength relief for itching and redness associated with minor skin irritations, inflammations, and rashes. It also relieves itching from eczema, psoriasis, insect bites, and other skin irritations. Each 1oz tube is tamper-proof and has a safety seal. The product is FDA registered with a National Drug Code Number and expiration date clearly printed on the packaging.

What We Like
Provides maximum strength relief for various itching and redness
Tamper-proof and safety sealed packaging
Contains 3 tubes of 1oz hydrocortisone cream
#TOP 10

Amazon Basic Care Hydrocortisone 1% Anti-itch Cream

Amazon Basic Care
1 Ounce (Pack of 1)
Amazon Basic Care Hydrocortisone 1% Anti-itch Cream Cover
Amazon Basic Care Maximum Strength Anti-Itch Cream, Hydrocortisone 1 Percent Intensive Healing Formula, Itch Relief For Bug Bites, Eczema, Psoriasis, Poison Ivy, Oak and Sumac, 1 ounce (Pack of 1)

Amazon Basic Care Hydrocortisone Cream is a powerful anti-itch cream that provides fast relief for various skin irritations. Its active ingredient, hydrocortisone 1%, is recommended by doctors and helps to alleviate itching caused by rashes, inflammation, insect bites, and more. With a maximum strength formula, this cream lasts up to 10 hours when used as directed. It is safe for sensitive skin and can be used by both adults and children aged 2 and older. Additionally, this intensive healing formula is clinically proven to moisturize for up to 24 hours, thanks to its nourishing ingredients like chamomile and Vitamins A, C, and E. With Amazon Basic Care Hydrocortisone Cream, you can experience fast and long-lasting relief from itching and irritation.

What We Like
Fast relief for itching
Maximum strength formula
Safe for sensitive skin
Buying Guide Image

Frequently Asked Questions (FAQs)

1. What is cortisone cream best for?

This medication is used to treat a variety of skin conditions (such as insect bites, poison oak/ivy, eczema, dermatitis, allergies, rash, itching of the outer female genitals, anal itching). Hydrocortisone reduces the swelling, itching, and redness that can occur in these types of conditions.

2. Can I buy cortisone cream over the counter?

Mild corticosteroids, such as clobetasone, hydrocortisone skin cream and hydrocortisone for piles and itchy bottom, can often be bought over the counter from pharmacies. Stronger types, such as beclometasone, betamethasone, clobetasol, fluticasone and mometasone, are only available on prescription.

3. What is better cortisone cream or ointment?

Creams are better for skin that is moist and weepy. Ointments are thicker and greasier, and are better for dry or flaky areas of skin. Most people need to use hydrocortisone cream or ointment once or twice a day.

Editor's Notes

During our creams cortisone treatment research, we found 24 creams cortisone treatment products and shortlisted 10 quality products. We collected and analyzed 220,429 customer reviews through our big data system to write the creams cortisone treatments list. We found that most customers choose creams cortisone treatments with an average price of $6.48.

The creams cortisone treatments are available for purchase. We have researched hundreds of brands and picked the top brands of creams cortisone treatments, including Cortizone 10, Globe, MED PRIDE, Globe Pharmacy, CareAll. The seller of top 1 product has received honest feedback from 385 consumers with an average rating of 4.7.

Written by
Bonnie Salem Avatar

Bonnie Salem is a stay-at-home mother with two-year-old twins and has spent almost half of her life surrounded by baby products. As a mother and a professional copywriter, she has an insightful and unique eye for researching products suitable for infants. Bonnie Salem is an expert in health and nutrition who lives with her family in New Jersey. She has over 15 years of working experience in an institute of medicine after graduating from the University of Toronto. She is highly interested in personal health and wellness.