Best Cortisone Treatments of 2026

"I found this cream to be highly effective at relieving itching and irritation very quickly. The texture is pleasant and not greasy, and it lasts a long time. In my experience, it works just as well as pricier brands but at a much more affordable price."

"When I had a flare-up of eczema and a mild rash, I tried this product and was impressed by its soothing and moisturizing qualities. It calmed my itchiness fast, felt gentle on my skin, and a small amount went a long way. I appreciate the value for size and price, and definitely recommend keeping it in your medicine cabinet or first aid kit."

"As someone dealing with minor irritation from balanitis, I was relieved to find this cream is safe for sensitive areas and provides fast relief. It's also effective on bug bites and offers a good amount for a low price. I find it very useful and versatile."

"I have very sensitive skin and often get rashes, but this cortisone cream is truly the best I’ve used. It provides quick relief from itching and is such a great value that I’ll keep buying it. I highly recommend it to anyone with similar skin issues."

"Summers where I live mean mosquito bites everywhere. This cream gives immediate itch relief and feels moisturizing and soothing. It doesn’t keep the itch away forever, but for quick comfort, it really works."

"Switching from expensive prescription creams to Cortizone was a great choice for my eczema. It keeps my skin moisturized, soothes itchiness within minutes, and doesn’t leave any sticky residue or irritating scents. My only gripe is the tube is smaller than it used to be, but it’s still the best option for my skin."

"I always keep this cream in my home because it's exceptional for calming angry or irritated skin—from rashes to burns or even poison ivy. It works within minutes, never stings, and leaves no sticky or unpleasant residue. The tube is easy to use, and a little goes a long way, making it a fantastic value compared to store prices."

"After trying a pricey anti-itch cream that did nothing, I switched to this one on a recommendation, and the relief was immediate. My skin gets irritated by synthetic fabrics, but this cream completely stops the itch and provides a cool, soothing feel. While I transition my wardrobe, this product is an absolute lifesaver."

"I have especially sensitive skin that flares up with heat rashes or bug bites, so this cortizone cream has become my go-to solution for any irritation. It cools and soothes my skin instantly, absorbs fast, and never feels greasy. The tube is generously sized, and I never run out because it honestly works wonders on my skin."

"I've had a severe, itchy scalp for months and tried countless treatments, but nothing worked until this. After just five days, my scalp is about 75% healed, and the itch is gone immediately after application. It's not oily and washes off easily. This product is effective and offers real value."

"My daughter has struggled with severe seborrheic dermatitis for years, and every other product either didn't work or made her hair brittle. After just one use of this treatment, her flakes disappeared for weeks, and her scalp stayed clear with just 1-2 applications a month. It's a real game changer for us, though I wish the bottle were bigger."

"For almost thirty years, I've battled a stubborn dry scalp patch. After using this product for less than a week, my scalp issue is 90% gone. The cooling tingle is satisfying, and there's no greasy feel or smell. For anyone with persistent scalp problems, this is a miracle in a bottle."

"I was skeptical at first because of the low price, but this cream truly delivers fast itch relief, even on sweaty feet. I now keep a tube handy in every bag I use. It's just as effective as expensive brands and not greasy at all."

"After struggling with eczema and trying several pricey creams that did nothing, I found that using this hydrocortisone cream three times a day cleared up my red, itchy skin within three days. Nothing else worked this well—it's the best by far."

"My husband has sensitive skin, and this product has been a real help. It goes on smoothly, isn’t greasy, and provides great value. We're both very pleased with the results."

"I've found this cream to be very effective for relieving skin itchiness, especially when other moisturizers didn't work for me. The price is much better than other options, and I've made it part of my daily routine. One minor complaint was the lid was on very tight, but it was worth it for how well the product performs."

"I bought this to deal with contact dermatitis from chlorine and sunscreen, and it really delivered great results. I appreciate that the tub is generously sized and should last a long time. The scent reminds me of band aids, but it fades quickly and doesn't bother me much."

"I've relied on this product for years for my husband's skin issues. However, since they switched to a bigger container with a plastic insert, I've noticed the cream is much thinner and watery. I still buy it out of necessity, but I really hope they bring back the original, thicker formula and packaging."

"I found that Cortizone-10 ointment delivers rapid relief from itching and irritation. The waterproof formula really lasts, and it keeps my skin feeling comfortable. Applying it is simple and mess-free."

"My doctor recommended Cortisone 10, but the cream version gave me a strong burning sensation. When I switched to the gel, it felt soothing and worked without pain or irritation. The gel was much gentler and calmed my skin fast."

"This ointment surpassed my expectations — it has no noticeable smell and quickly stopped my itching and discomfort. It even helped heal my rash and redness. The 2oz size is practical, though I agree the box could be sturdier."

"I've found this ointment to be incredibly effective for relieving itchiness, both for myself and my grandkids. My skin is sensitive and dry, and a small amount of this prevents me from scratching and breaking the skin. I always keep it handy."

"This ointment was a lifesaver during our trip to Mexico. Both my baby and I got lots of bug bites, and the relief was almost immediate. I also noticed there’s no strong smell and the texture is light enough that my toddler doesn't mind it."

"I really like that this product combines Aquaphor and hydrocortisone. It’s super convenient for treating my kids’ rashes and eczema. The only downside is I wish it were a bit more affordable."

"I've battled with extremely sensitive skin and even Aveeno was too harsh for me, but this ointment was a lifesaver. It’s gentle, spreads easily, and instantly soothes irritation. Yes, it leaves a bit of a slippery feel, but the relief it delivers is absolutely worth it."

"After trying every cheaper alternative, this is the only product that actually works for my chronic itching due to hidradenitis. It acts fast, lasts all day, and even though it's pricier, I’ll keep buying it because nothing else compares in effectiveness and duration."

"My son struggled with diaper rash for ages, and this is the only cream that clears it up quickly. Just a little bit on irritated skin and the rash disappears in hours. It feels like magic—highly recommended for parents!"

"I found this product to be extremely helpful for calming itching and it’s also simple to open and use. It really supported the healing process, which I appreciate."

"After developing an allergy to flower seeds, I used this and it made my recovery much easier."

"I was amazed by how well this worked for me—just a small amount eased my skin irritation and reduced redness. I’ve tried many calming lotions, but nothing else has been this effective!"