Best Cortisone Treatments of 2025

Bonnie Salem Avatar
Bonnie Salem
Last Updated: Jan 14, 2025

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Cortisone treatments are a type of medication used to reduce inflammation and swelling in the body. They are often prescribed by doctors to treat conditions such as arthritis, asthma, and skin disorders. Cortisone is a steroid hormone that is naturally produced by the body's adrenal gland, but can also be manufactured as a medication. Cortisone treatments are available in various forms, including pills, injections, and creams. While they can be effective in reducing inflammation, cortisone treatments can also have side effects, such as weight gain, mood changes, and weakened immune system. It is important to consult with a doctor before starting any cortisone treatment.

At a Glance: Our Top Picks

Amazon Basic Care Hydrocortisone 1% Anti-itch Cream Cover #TOP 1
Amazon Basic Care Hydrocortisone 1% Anti-itch Cream
ftb score rating icon 9.8
Cortizone-10 Maximum Strength Anti-Itch Cream Cover #TOP 2
Cortizone-10 Maximum Strength Anti-Itch Cream
ftb score rating icon 9.7
Cortizone 10 Maximum Strength Cream Cover #TOP 3
Cortizone 10 Maximum Strength Cream
ftb score rating icon 9.5

Top 10 Cortisone Treatments

#TOP 1

Amazon Basic Care Hydrocortisone 1% Anti-itch Cream

Amazon Basic Care
1 Ounce (Pack of 1)
Amazon Basic Care Hydrocortisone 1% Anti-itch Cream Cover
Amazon Basic Care Maximum Strength Anti-Itch Cream, Hydrocortisone 1 Percent Intensive Healing Formula, Itch Relief For Bug Bites, Eczema, Psoriasis, Poison Ivy, Oak and Sumac, 1 ounce (Pack of 1)

Amazon Basic Care Hydrocortisone Cream is a powerful anti-itch cream that provides fast relief for various skin irritations. Its active ingredient, hydrocortisone 1%, is recommended by doctors and helps to alleviate itching caused by rashes, inflammation, insect bites, and more. With a maximum strength formula, this cream lasts up to 10 hours when used as directed. It is safe for sensitive skin and can be used by both adults and children aged 2 and older. Additionally, this intensive healing formula is clinically proven to moisturize for up to 24 hours, thanks to its nourishing ingredients like chamomile and Vitamins A, C, and E. With Amazon Basic Care Hydrocortisone Cream, you can experience fast and long-lasting relief from itching and irritation.

What We Like
Effective quick relief
Absorbs without greasy residue
Affordable price point
Versatile for various skin issues
Long-lasting soothing effect
What We Don't Like
Strong scent
May require reapplication
#TOP 2

Cortizone-10 Maximum Strength Anti-Itch Cream

SA00215
Multicolor
2 Ounce (Pack of 1)
Cortizone-10 Maximum Strength Anti-Itch Cream Cover
Cortizone 10 Maximum Strength Anti-Itch Cream with Soothing Aloe, 1% Hydrocortisone Creme, 2 oz.

Cortizone-10 Anti-Itch Cream is a maximum-strength cream that provides fast relief for itch and inflammation associated with eczema, psoriasis, and poison oak, ivy, and sumac. With its 1% hydrocortisone formula, this cream offers the highest level of itch relief without a prescription. In just under 10 minutes, it effectively relieves itch and provides long-lasting relief that lasts for hours. The cream is also fragrance-free and dye-free, making it suitable for those with sensitive skin. Cortizone-10 Anti-Itch Cream is the #1 Doctor-Recommended OTC Anti-Itch Brand, according to a 2021 IQVIA Study. Experience the soothing and fast-acting relief of Cortizone-10 Anti-Itch Cream today!

What We Like
Effective itch relief
Moisturizing with soothing aloe
Great value for the price
Convenient size for travel
Quick-acting formula
What We Don't Like
Can get chalky if not cleaned
May need reapplication during sweating
#TOP 3

Cortizone 10 Maximum Strength Cream

842805
White
2 Ounce (Pack of 1)
Cortizone 10 Maximum Strength Cream Cover
Cortizone 10 Maximum Strength Intensive Moisture Anti-Itch Cream, 1% Hydrocortisone, 2 oz.

Cortizone 10 Anti-Itch Cream provides quick relief from itchiness caused by minor skin irritations such as dryness and chafing. With its powerful 1% hydrocortisone formula, you can expect noticeable results in under 10 minutes. This cream also includes seven moisturizers and essential vitamins A, C, and E, ensuring that your skin stays nourished and hydrated. Enjoy the convenience of 24-hour moisture without any fragrances or dyes, making it gentle for all skin types. Experience effective itch relief without needing a prescription.

What We Like
Quick relief from itchiness
Gentle on sensitive skin
Non-greasy and absorbs quickly
Effective for various skin issues
Convenient travel size
What We Don't Like
Packaging issues reported
#TOP 4

Globe Hydrocortisone Cream

Globe
8899-FBA-4
1 Ounce (Pack of 4)
Globe Hydrocortisone Cream Cover
Globe (4 Pack) Hydrocortisone Maximum Strength Anti-Itch Cream 1% w/Aloe, Intensive Formula for Redness, Rash, Bug & Mosquito Bites, Eczema, Hemorrhoids, Sensitive Skin, Instant Itch Relief,1 oz Tube

Globe Hydrocortisone Cream is a fast and effective solution for skin irritation and rashes. With the power of hydrocortisone 1% and the soothing properties of aloe vera, it provides relief for inflammation, redness, and itching caused by insect bites, poison ivy, oak, and sumac. It is also beneficial for conditions like eczema, psoriasis, and seborrheic dermatitis. This pharmacist-recommended cream is safe for adults and children 12 years and older. It can be used as a home remedy or included in your first aid kit for immediate relief. Globe Hydrocortisone Cream comes in a pack of 4 tubes, offering amazing value compared to leading brands.

What We Like
Effective relief for various skin issues
Affordable alternative to name brands
Convenient multi-pack value
Durable, leak-proof packaging
Same active ingredient as expensive brands
What We Don't Like
Limited availability noted by users
#TOP 5

Cortizone-10 Maximum Strength Fast Itch Relief

Multicolor
Cortizone-10 Maximum Strength Fast Itch Relief Cover
Cortizone 10 Maximum Strength Fast Itch Relief with Massaging Rollerball, 1% Hydrocortisone Anti-Itch Liquid, 1.5 oz.

Cortizone-10 Maximum Strength Fast Itch Relief with Massaging Rollerball is a 1.5 oz. tube that provides fast relief for itch and inflammation resulting from rashes, insect bites, and ivy and sumac. It features 1% hydrocortisone, which is the maximum-strength itch relief without a prescription. This itch relief liquid is fragrance-free and absorbs quickly. The massaging rollerball applicator allows for no-mess, no-touch relief. Cortizone-10 is the #1 Doctor-Recommended OTC Anti-Itch Brand* *2021 IQVIA Study.

What We Like
Quick itch relief
No mess application
Compact and travel-friendly
Absorbs quickly
Lightweight and easy to store
What We Don't Like
Applicator can be tight
Initial application may be tricky
#TOP 6

Cortizone-10 Ultra Soothing Anti-Itch Cream

Multicolor
2 Ounce (Pack of 1)
Cortizone-10 Ultra Soothing Anti-Itch Cream Cover
Cortizone 10 Maximum Strength Ultra Soothing Anti-Itch Cream, 1% Hydrocortisone Creme, 2 oz.

Cortizone-10 Ultra Soothing Anti-Itch Cream, also known as Cortizone-10 Itch Cream, is a maximum strength cream that provides fast relief for itch and inflammation associated with eczema, psoriasis, and poison oak, ivy, and sumac. With its 1% hydrocortisone formula, this cream offers maximum-strength itch relief without a prescription. It contains 10 moisturizers and aloe, which help to soften and soothe the skin. The cream is non-irritating, fragrance-free, and dye-free, making it suitable for sensitive skin. Cortizone-10 Ultra Soothing Anti-Itch Cream provides quick relief in under 10 minutes and lasts for hours, allowing you to go about your day without the discomfort of itching and inflammation.

What We Like
Quick relief from itching
Effective for various skin irritants
Non-greasy cream option
Trusted brand with quality
Good value for the price
#TOP 7

Cortizone 10 Maximum Strength Ointment

Multicolor
2 Ounce (Pack of 1)
Cortizone 10 Maximum Strength Ointment Cover
Cortizone 10 Maximum Strength Water Resistant Anti-Itch Ointment, 1% Hydrocortisone, 2 oz.

Cortizone 10 Anti-Itch Ointment is designed to provide quick relief from itching and inflammation caused by conditions like eczema, psoriasis, and reactions to poison ivy, oak, or sumac. This ointment contains 1% hydrocortisone, offering maximum-strength relief without needing a prescription. Its water-resistant formula, enriched with petrolatum, helps create a protective barrier on your skin while locking in moisture. You can expect relief in under 10 minutes, with effects that last for hours, making it a convenient choice for those seeking effective itch relief.

What We Like
Fast itch relief
Good value for money
Long-lasting effectiveness
Convenient online ordering
Suitable for various skin irritations
What We Don't Like
Ointment is slightly greasy
May not suit everyone's preference
#TOP 8

Globe Hydrocortisone Maximum Strength Cream 1% w/Aloe, 16 oz

Globe
8897-FBA
White Cream
16 Ounce
Globe Hydrocortisone Maximum Strength Cream 1% w/Aloe, 16 oz Cover
Globe Hydrocortisone Maximum Strength Cream 1% w/Aloe, 16 oz, Anti-Itch Cream for Redness, Swelling, Itching, Rash, Bug/Mosquito Bites, Eczema, Hemorrhoids & More, 16 oz Jar

Globe Hydrocortisone Maximum Strength Cream combines hydrocortisone 1% with aloe vera, providing fast and effective relief for skin irritation, rashes, inflammation, redness, insect bites, poison ivy, oak, and sumac. It can also ease the symptoms of eczema, psoriasis, and other forms of dermatitis. This safe and effective home remedy is recommended by pharmacists and comes in a 16 oz jar for the price of 2 oz of the leading name brand.

What We Like
Great for sensitive dry skin
Cost-effective compared to smaller sizes
Good quality and quick shipping
Easy to use and spreads well
What We Don't Like
Somewhat thick texture
#TOP 9

Vanicream 1% Hydrocortisone Anti-Itch Cream

No Model
White
2 Ounce (Pack of 1)
Vanicream 1% Hydrocortisone Anti-Itch Cream Cover
Vanicream 1% Hydrocortisone Anti-Itch Cream - 2 oz - Maximum OTC-Strength Formula for Sensitive Skin

Vanicream Anti-Itch Cream is a maximum strength over-the-counter hydrocortisone cream that provides fast relief from flare-ups due to eczema, dermatitis, and psoriasis. It is specially formulated for sensitive skin and does not cause blackheads, making it suitable for use on the face. The cream is free of common chemical irritants such as dyes, fragrance, and parabens. Dermatologist tested, it contains ingredients that are considered desirable and not irritating or sensitizing to the skin. Whether you're dealing with itchy skin caused by eczema or other skin conditions, Vanicream Anti-Itch Cream offers ultimate relief in a mild and gentle formula.

What We Like
Effective anti-itch relief
Gentle on sensitive skin
Non-greasy texture
Fragrance-free formulation
Trusted brand with loyal customers
What We Don't Like
Perceived lower potency
#TOP 10

Medpride Hydrocortisone 1% Anti Itch Cream

Medpride Hydrocortisone 1% Anti Itch Cream Cover
Medpride 1% Hydrocortisone Cream - Maximum Strength Itch Relief for Mosquito Bites, Eczema, Dermatitis - 16 oz

Medpride Hydrocortisone 1% Anti Itch Cream provides instant relief against itch, rash, and pain caused by skin conditions such as eczema, dermatitis, skin rashes, allergic reactions, and hyper-sensitive skin. Suitable for all skin types, including children, it has a fast-acting formula that delivers instant results without causing any discomfort. Its maximum strength formula contains 1% hydrocortisone, which combats redness, swelling, and inflammation, making it a proven effective solution for an array of skin conditions. You can apply the cream up to 3 times a day to the affected area and soon all the pain and discomfort will be gone.

What We Like
Long-lasting product
Economical packaging
Effective itch relief
Good price compared to competitors
What We Don't Like
Lid difficult to operate
Unpleasant smell
Buying Guide Image

Get the Best Cortisone Treatments

What is Cortisone?

Cortisone is a type of steroid hormone that is naturally produced by the body's adrenal gland. It plays a crucial role in the body's immune system, helping to regulate inflammation and other immune responses. However, cortisone can also be synthesized in a laboratory and used as a medication to treat a variety of conditions.

Why Might Someone Need Cortisone Treatment?

Cortisone is often used to treat inflammatory conditions, such as allergies, asthma, and rheumatoid arthritis. It can also be used to treat certain skin conditions, such as eczema and psoriasis, and to reduce swelling and inflammation in the joints and other tissues. In some cases, cortisone may be used as a pain reliever or to suppress the immune system to prevent rejection of transplanted organs.

How is Cortisone Treatment Administered?

Cortisone can be administered in several ways, depending on the condition being treated and the severity of the symptoms. It can be taken orally, applied topically as a cream or ointment, injected into a muscle or joint, or inhaled through an inhaler.

How to Choose the Right Cortisone Treatment

When considering cortisone treatment, it is important to work with a healthcare provider who can help you determine the best course of action. This may involve discussing your medical history, performing a physical examination, and conducting any necessary tests to diagnose the underlying condition.

Once a diagnosis has been made, your healthcare provider will recommend a treatment plan that is tailored to your specific needs. This may include a combination of different cortisone treatments, as well as other medications or therapies.

It is also important to carefully consider the potential risks and benefits of cortisone treatment. While cortisone can be effective in reducing inflammation and providing relief from symptoms, it can also cause side effects, such as weight gain, mood changes, and thinning of the skin. In some cases, long-term use of cortisone may lead to more serious complications, such as osteoporosis or gastrointestinal ulcers.

Conclusion

Cortisone treatment can be an effective way to manage inflammation and relieve symptoms of certain medical conditions. However, it is important to work with a healthcare provider to determine the right course of action and to carefully consider the potential risks and benefits of cortisone treatment.

Frequently Asked Questions (FAQs)

1. What are the possible side effects of cortisone treatment?

Possible side effects of cortisone treatment include skin thinning, loss of color in the skin, intense pain (post-injection flare), facial flushing, insomnia, and high blood sugar. It's important to be aware of these potential side effects when considering cortisone treatment.

2. How long do cortisone injections last for?

The effects of a cortisone injection can last anywhere from 6 weeks to 6 months. Cortisone reduces inflammation, which can provide temporary relief and make you feel better during that time.

3. Is a cortisone shot a big deal?

Cortisone shots are generally safe, and the risk of side effects is rare. However, overusing cortisone can lead to potential risks, such as long-lasting skin discoloration and ruptured tendons. It's important to use cortisone shots judiciously and under the guidance of a healthcare professional.

4. Are cortisone injections worth having?

Cortisone injections may provide temporary pain relief and improve function in the short term. However, it's important to note that these injections may not be beneficial for long-term joint health. Adverse events associated with cortisone shots are being increasingly recognized, and physicians should carefully consider the potential risks before recommending them.

5. Who should avoid cortisone?

Cortisone injections are not recommended for patients with existing infections, including skin infections and septic arthritis. Additionally, patients taking blood thinners or those with broken bones may not be suitable candidates for cortisone injections. It's important to consult with a healthcare professional to determine if cortisone is appropriate for your situation.

6. Is there a downside to cortisone shots?

While there is a potential for complications such as cartilage damage, bone death, joint infection, and nerve damage, these complications are exceedingly rare when the cortisone shot is administered by an experienced doctor. It's important to choose a qualified healthcare professional to minimize the risks associated with cortisone shots.

7. Why are doctors hesitant for cortisone shots?

Doctors may be hesitant to administer repeated cortisone shots due to concerns about potential damage to the cartilage within a joint. Limiting the number of cortisone shots into a joint helps minimize the risk of cartilage damage and other complications.

8. Why do doctors not like to give cortisone shots?

Doctors may be cautious about giving cortisone shots due to concerns about potential damage to the cartilage within a joint. Minimizing the number of cortisone shots helps reduce the risk of cartilage damage and other complications.

Editor's Notes

During our cortisone treatment research, we found 25 cortisone treatment products and shortlisted 10 quality products. We collected and analyzed 247,370 customer reviews through our big data system to write the cortisone treatments list. We found that most customers choose cortisone treatments with an average price of $7.12.

The cortisone treatments are available for purchase. We have researched hundreds of brands and picked the top brands of cortisone treatments, including Cortizone 10, Globe, Vanicream, MED PRIDE. The seller of top 1 product has received honest feedback from 385 consumers with an average rating of 4.7.

Written by
Bonnie Salem Avatar

Bonnie Salem is a stay-at-home mother with two-year-old twins and has spent almost half of her life surrounded by baby products. As a mother and a professional copywriter, she has an insightful and unique eye for researching products suitable for infants. Bonnie Salem is an expert in health and nutrition who lives with her family in New Jersey. She has over 15 years of working experience in an institute of medicine after graduating from the University of Toronto. She is highly interested in personal health and wellness.

Cortisone Treatments Comparison Table

#TOP1
#TOP2
#TOP3
#TOP4
#TOP5
#TOP6
#TOP7
#TOP8
#TOP9
#TOP10
Brand Amazon Basic Care Cortizone 10 Cortizone 10 Globe Cortizone 10 Cortizone 10 Cortizone 10 Globe Vanicream MED PRIDE
Special Feature Clinically Proven fast_acting Anti itch Clinically Proven fast_acting clinically_proven Fast-Acting Fast-Acting Anti-Itch fast-acting
Item dimensions L x W x H 1.06 x 1.5 x 5.75 inches 1.44 x 5.75 x 2.75 inches - 4 x 1 x 7 inches 1.58 x 3 x 5.78 inches 1.44 x 5.75 x 2.75 inches 1.44 x 5.75 x 2.75 inches 5 x 5 x 7 inches 1.75 x 1.75 x 5.5 inches -
Product Benefits Itch Control Itch Control - Swelling, Itch Control Itch Control Itch Control Itch Control Dermatitis, Eczema, Mosquito - Anti Itch,Itch Relief
Item Weight - 2.9 Ounces - 0.06 Pounds 1.5 Ounces 0.18 Pounds - 1 Pounds - 1 Pounds
FTB Score
ftb score rating icon 9.8
ftb score rating icon 9.7
ftb score rating icon 9.5
ftb score rating icon 9.4
ftb score rating icon 9.3
ftb score rating icon 9.3
ftb score rating icon 9.2
ftb score rating icon 9.0
ftb score rating icon 9.0
ftb score rating icon 9.0
Where to Buy