Best Zinc Pyrithione Conditioner of 2026

The CeraVe Anti Dandruff Conditioner is designed to help you get rid of dandruff effectively with its 0.5% Pyrithione Zinc formula, which reduces flakes and soothes itchy, irritated scalp. It also keeps your hair and scalp hydrated using a blend of ceramides, niacinamide, and hyaluronic acid, helping to maintain your hair’s natural moisture. This conditioner works best when paired with CeraVe’s Anti-Dandruff Shampoo, leaving your hair feeling soft, nourished, and healthy. Developed with dermatologists, it’s gentle enough for sensitive scalps, safe for color-treated hair, and free from harsh ingredients like sulfates and parabens.

Head and Shoulders Royal Oils Moisture Renewal Conditioner is a rich and creamy formula that restores moisture to hair and scalp, leaving you with touchably soft and healthy hair. It is expertly designed to provide scalp relief for natural, relaxed, kinky, and coily crowns. It is free of sulfates, parabens, and dyes, and has a fresh coconut scent. Customers have reported that it helps to reduce dandruff and itching, and brings great moisture to brittle hair. It is suitable for all hair types, including bleached blonde hair.

Head & Shoulders Supreme Sulfate Free Conditioner with Argan Oil, Anti-Dandruff Treatment, Soothe & Strengthen Hair & Scalp, 28.2 Fl Oz is a large sized bottle of conditioner that works well. It is free from parabens, dyes, phosphates, phthalates, silicones and sulfated surfactants, and is infused with rose essence and naturally derived argan oil. It soothes scalp discomfort and strengthens hair at the root, and is clinically proven to protect against flakes, itch, oil and dryness with regular use. It has a strong perfume smell, but this rinses out okay and only lingers a bit. It is a little drying in hair, but overall it is a good product and will work well for most.

The Otter co. Dandruff Conditioner Bar is designed to help you fight flakes and soothe an itchy scalp with natural ingredients like tea tree oil, apple cider vinegar, and zinc Pyrithione. These work together to calm irritation and reduce dandruff quickly. This bar uses plant-based ingredients, including nourishing argan oil, shea butter, and coconut milk, providing a gentle yet effective conditioning experience without harsh chemicals or sulfates. Plus, it’s a low-waste option, packaged in compostable materials, making it easy to carry around and eco-friendly. By choosing this bar, you also support wildlife conservation efforts, giving your hair care routine a meaningful purpose.

The Dove Scalp Conditioner is designed to soothe and care for your scalp, helping to reduce irritation and dandruff with the power of Zinc Pyrithione. This means you can enjoy a more comfortable and flake-free scalp. It works to remove up to 100% of visible flakes when used regularly, leaving your hair smooth and dandruff-free from root to tip. The conditioner also helps repair your scalp’s natural moisture barrier with ingredients like Niacinamide and Glycerin, promoting a healthier scalp environment. Developed with dermatologists, this conditioner supports your scalp care routine with trusted and effective ingredients.

The Biolage Scalp Sync conditioner is designed to care for all scalp types while keeping your hair nourished and hydrated. It works alongside the Scalp Sync shampoo, which contains zinc pyrithione to help reduce dandruff symptoms effectively. This conditioner deeply cleanses your scalp and hair without stripping away natural oils, so your scalp stays balanced and healthy. It also helps control visible flakes and soothes any irritation you may experience. Plus, it leaves your hair with Biolage’s signature fresh fragrance, making your hair care routine both effective and pleasant.

Dove DermaCare Scalp Anti-Dandruff Conditioner is a fragrant and indulgent conditioner that is formulated to tackle dandruff effectively. It is designed to nourish and hydrate hair while providing relief to a dry and itchy scalp. The conditioner contains active Pyrithione Zinc that helps to control dandruff and reduce scalp redness. Additionally, this conditioner also smooths strands for less frizzy hair, working as an anti-dandruff frizz control hair product. With the regular use of this conditioner, you can get flake-free hair with no visible flakes.

As I Am Dry & Itchy Scalp Care Conditioner is a rinse-out conditioner enriched with Zinc Pyrithione, Olive Oil, and Tea Tree Oil to fight dandruff and Seborrheic Dermatitis. It moisturizes and promotes shine, strengthens and repairs hair, and improves scalp moisture by 148%. Customers have reported that it relieves scalp itch, flaking, and irritation associated with Seborrheic Dermatitis and Dandruff, and improves detangling of curls by 49%.

Teenology Detangler is a hair conditioning and heat protectant product specially designed for teens. It stands out from other hair care products because it is free from harmful ingredients like sulfates and parabens that can cause acne breakouts. With its deeply moisturizing ingredients such as comfrey, sage, and grapefruit extracts, as well as aloe vera and vitamin B5, this detangler not only conditions and hydrates the hair but also removes knots, tangles, and frizz, leaving the hair soft, shiny, and easy to manage. It also helps to promote clear skin by unblocking pores and reducing redness with sage, comfrey, and grapefruit peel extract. The addition of zinc pyrithione, recommended by dermatologists for fighting acne, further enhances its skin-clearing properties. The refreshing grapefruit scent uplifts the senses, relieving stress and boosting energy. Teenology Detangler is a premium product that is silicone-free, gluten-free, cruelty-free, soy-free, phthalate-free, and color safe, making it suitable for all hair types and ages.

Free & Clear Medicated Anti-Dandruff Shampoo is a protein-free, sulfate-free, and gluten-free formula that is dermatologist-tested and effective against dandruff and seborrheic dermatitis. It is made with maximum OTC strength zinc pyrithione 2% and is free of common chemical irritants such as dyes, fragrance, and parabens.