Best Baby Formula for Colic of 2025

Elisa Drew Avatar
Elisa Drew
Last Updated: Jan 7, 2025

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If your baby is suffering from colic, finding the right formula can make all the difference. There are a variety of baby formulas on the market that are designed to ease colic symptoms and provide relief for both baby and parents. Some popular options include Enfamil Gentlease, Similac Sensitive, and Gerber Good Start Soothe. These formulas are specially designed with gentle, easy-to-digest proteins and prebiotics to help soothe a baby's digestive system and reduce fussiness and gas. Always consult with your pediatrician before making any changes to your baby's diet.

At a Glance: Our Top Picks

Similac Alimentum Infant Formula Cover #TOP 1
Similac Alimentum Infant Formula
ftb score rating icon 9.8
Enfamil Nutramigen Hypoallergenic Baby Formula Cover #TOP 2
Enfamil Nutramigen Hypoallergenic Baby Formula
ftb score rating icon 9.7
Enfamil Nutramigen Hypoallergenic Formula Cover #TOP 3
Enfamil Nutramigen Hypoallergenic Formula
ftb score rating icon 9.5

Top 10 Baby Formula for Colic

Similac Alimentum Infant Formula

Similac Alimentum Infant Formula Cover
Similac Alimentum with 2’-FL HMO Hypoallergenic Infant Formula, for Food Allergies and Colic,* Suitable for Lactose Sensitivity, Baby Formula Powder, 19.8-oz Value Can

Similac Alimentum Formula by Similac is a hypoallergenic powder baby formula designed for infants with food allergies and colic. It contains a special milk protein that helps reduce allergic reactions in babies sensitive to cow's milk protein. This formula starts alleviating colic symptoms within 24 hours for most babies. Additionally, it is the first formula to include 2'-FL HMO, an immune-nourishing ingredient. Moreover, it is EBT eligible, making it accessible for purchase with SNAP benefits in select stores.

What We Like
Hypoallergenic formula
Reduces colic symptoms
Contains immune-nourishing ingredient

Enfamil Nutramigen Hypoallergenic Baby Formula

Enfamil Nutramigen Hypoallergenic Baby Formula Cover
Enfamil Nutramigen Hypoallergenic Baby Formula with Iron, Lactose Free, Colic Relief from Cow's Milk Allergy Starts in 24 Hours, Brain Building DHA, Probiotic LGG for Immune Support, 27.8 Oz Can

Enfamil Nutramigen Formula is a gentle, lactose-free powder baby formula designed to help ease your little one's colic, providing fast relief within 48 hours. It features the superstar LGG probiotic, supporting your baby's digestive health. With nourishing brain development components like omega-3 DHA and ARA, it aids in your baby's brain growth. Additionally, it offers immunity support, helping your baby adapt to standard milk formula. Trusted by pediatricians, this formula is a top choice for managing cow's milk allergy, ensuring a happier, better-rested baby and mom.

What We Like
Colic relief
Fast improvement
Brain development support

Enfamil Nutramigen Hypoallergenic Formula

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Enfamil Nutramigen Hypoallergenic Formula Cover
Enfamil Nutramigen Baby Formula, Hypoallergenic and Lactose Free Formula with Enflora LGG, Fast Relief from Severe Crying and Colic, Powder Can, 19.8 Oz (Pack of 1)

Enfamil Nutramigen Formula is designed to help ease your baby's colic caused by cow's milk allergies. It provides gentle relief, often reducing excessive crying in less than a day, making for a happier baby and a more restful parent. This formula features LGG probiotic, which supports your baby's digestive health, ensuring they feel their best. Additionally, it's hypoallergenic with hydrolyzed proteins, minimizing the risk of allergic reactions, and it's lactose-free, perfect for babies with lactose intolerance. With Nutramigen, you can feel confident knowing you're giving your little one a soothing solution.

What We Like
Clinically proven colic relief
Fast reduction of crying
Supports digestive health
Hypoallergenic and lactose-free
#TOP 4

Enfamil Nutramigen Infant Formula

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Enfamil Nutramigen Infant Formula Cover
Enfamil Nutramigen Hypoallergenic Baby Formula with Iron, Lactose Free, Colic Relief from Cow's Milk Allergy Starts in 24 Hours, Brain Building DHA, Probiotic LGG for Immune Support, 32 Fl Oz, 6 Count

Enfamil Nutramigen Formula is a liquid baby formula that provides fast relief from severe crying and colic due to cow's milk allergy. It includes LGG, a probiotic that supports digestive health, and important nutrients found in breast milk such as omega-3 DHA, ARA, and choline that provide brain support. This lactose-free formula helps support baby's immune system and is recommended by pediatricians. With 90% of infants improving within 48 hours, Enfamil Nutramigen Formula is a trusted brand for allergy management, brain-building, and immune support.

What We Like
Fast relief from colic
Brain support nutrients
Trusted brand for allergy management

Gerber Good Start Baby Formula Powder

Good Start
Gerber Good Start Baby Formula Powder Cover
Gerber Good Start Baby Formula Powder, SoothePro Comforting Probiotics, Stage 1, 12 Ounces

Features
Probiotic Formula: Good Start Soothe Formula Features Prebiotics, Comfort Proteins And Probiotics That Improve The Good Bacteria In Tummies And Promote Soft Stools; It's Our Closest Formula To Breastmilk
Soothing Nutrition: Modeled After The Complete Nutrition And Gentleness Of Breastmilk, This Formula Offers Nutrition For Babies Up To 12 Months Experiencing Colic, Excessive Crying, Fussiness And Gas
Wholesome Options: Introduce Your Infant To Complimentary Staged Products Like Single Grain Cereals And 1st Foods Fruit And Veggie Purees With Gerber Infant Formulas, Probiotic Supplements And More
Nutrition For Growing: Like Your Baby, We're Always Growing And Learning. More Than Ever We're Committed To Being Your Partner In Parenthood With Quality Ingredients, Nutritious Food And Expert Guidance
Give Your Baby A Good Start: Your Baby's Nutritional Needs Evolve Over Time. That's Why We Created The Gerber Good Start Line. Made To Comfort Your Baby's Tummy And Available In A Range Of Products
#TOP 6

Enfamil Nutramigen Infant Formula, Lactose Free, 6 Liquid Bottles (4 Count)

Nutramigen
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Enfamil Nutramigen Infant Formula, Lactose Free, 6 Liquid Bottles (4 Count) Cover
Enfamil Nutramigen Baby Formula, Hypoallergenic and Lactose Free Formula with Enflora LGG, Fast Relief from Severe Crying and Colic, Ready to Use Bottle, 8 Fl Oz (24 Count) (Pack of 4)

The Enfamil Nutramigen Infant Formula is a lactose-free and hypoallergenic baby formula designed to provide fast relief from colic caused by cow's milk allergy. It includes LGG, a probiotic that helps manage allergies and supports digestion. Nutramigen also contains important nutrients like omega-3 DHA, ARA, and choline that provide brain and immune support for the baby. Clinically proven to provide relief as early as the first feeding, it helps the baby's immune system return to consuming traditional milk protein formula without an allergic response. Enfamil Nutramigen Infant Formula is the #1 trusted brand for brain-building and immune support, and is recommended by pediatricians.

What We Like
Provides fast relief from colic due to cow's milk allergy
Includes LGG probiotic for allergy management and digestion support
Contains important nutrients like omega-3 DHA, ARA, and choline for brain and immune support
#TOP 7

Gerber Good Start Baby Formula Powder

Good Start
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Gerber Good Start Baby Formula Powder Cover
Gerber Good Start Baby Formula Powder, SoothePro Comforting Probiotics, Stage 1, 30.6 Ounce

Features
Probiotic Formula: Good Start Soothe Formula Features Prebiotics, Comfort Proteins And Probiotics That Improve The Good Bacteria In Tummies And Promote Soft Stools; It's Our Closest Formula To Breastmilk
Soothing Nutrition: Modeled After The Complete Nutrition And Gentleness Of Breastmilk, This Formula Offers Nutrition For Babies Up To 12 Months Experiencing Colic, Excessive Crying, Fussiness And Gas
Wholesome Options: Introduce Your Infant To Complimentary Staged Products Like Single Grain Cereals And 1st Foods Fruit And Veggie Purees With Gerber Infant Formulas, Probiotic Supplements And More
Nutrition For Growing: Like Your Baby, We're Always Growing And Learning. More Than Ever We're Committed To Being Your Partner In Parenthood With Quality Ingredients, Nutritious Food And Expert Guidance
Give Your Baby A Good Start: Your Baby's Nutritional Needs Evolve Over Time. That's Why We Created The Gerber Good Start Line. Made To Comfort Your Baby's Tummy And Available In A Range Of Products
#TOP 8

Gerber Good Start Baby Formula Powder

Good Start
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Gerber Good Start Baby Formula Powder Cover
Gerber Good Start Baby Formula Powder, SoothePro, Stage 1, 19.4 Ounce

Gerber Good Start Baby Formula Powder, also known as Gerber Formula Powder, is a high-quality baby formula that provides soothing nutrition for babies up to 12 months. It is specially formulated for babies experiencing colic, excessive crying, fussiness, and gas. The formula is modeled after the complete nutrition and gentleness of breastmilk, making it an ideal choice for parents looking for a formula that closely resembles breastmilk. It contains prebiotics, Comfort Proteins, and probiotics that improve the good bacteria in babies' tummies and promote soft stools. With Gerber Good Start Baby Formula Powder, you can give your baby a good start and meet their evolving nutritional needs. In addition to the formula, Gerber offers a range of complimentary staged products like single grain cereals and fruit and veggie purees, providing wholesome options for your growing baby. Choose Gerber Good Start Baby Formula Powder for quality ingredients, nutritious food, and expert guidance in parenthood.

What We Like
Soothing nutrition
Modeled after breastmilk
Improves good bacteria
#TOP 9

Nutricia Pepticate Baby Formula

NUTRICIA PEPTICATE
Nutricia Pepticate Baby Formula Cover
Pepticate Baby Formula, Hypoallergenic Powdered Infant Formula for Cow Milk Allergy, with Omega 3 DHA, ARA, Iron & Prebiotics, 13.2oz

Pepticate Formula is a hypoallergenic powdered infant formula by Nutricia Pepticate, designed for infants with cow milk allergy. It has over 30 years of experience managing cow milk allergy symptoms like eczema and colic. Inspired by breast milk, it contains prebiotic oligosaccharides for digestive health, nucleotides for the immune system, and DHA plus ARA for brain and eye development. Made in Europe, it's a safe and well-tolerated formula trusted in over 75 countries.

What We Like
Hypoallergenic for cow milk allergy
Contains essential nutrients
Trusted brand with experience
#TOP 10

Enfamil Nutramigen Baby Formula, Hypoallergenic and Lactose Free Formula with Enflora LGG, Fast Relief from Severe Crying and Colic

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Gold and White Can
Enfamil Nutramigen Baby Formula, Hypoallergenic and Lactose Free Formula with Enflora LGG, Fast Relief from Severe Crying and Colic Cover
Enfamil Nutramigen Baby Formula, Hypoallergenic and Lactose Free Formula with Enflora LGG, Fast Relief from Severe Crying and Colic, Powder Can, 12.6 Oz (6 Count)

Enfamil Nutramigen Infant Formula is a hypoallergenic and lactose-free formula that is designed to provide fast relief from severe crying and colic. It contains clinically proven ingredients such as extensively hydrolyzed proteins, LGG probiotic, omega-3 DHA, ARA, and choline to provide brain support and immune system support. It is the #1 trusted brand recommended by pediatricians and is available in powder form. Customers are satisfied with the product, however, the price is too high and some customers have experienced damaged cans on delivery.

What We Like
Clinically proven relief for colic due to cow’s milk allergy
Contains LGG probiotic for allergy management
Omega-3 DHA, ARA, and choline for brain support
Immune support
#1 trusted brand
Pediatrician recommended
Buying Guide Image

Frequently Asked Questions (FAQs)

1. What formula is best for colic baby?

Best baby formulas. Best baby formula for colic: Gerber Good Start SoothePro Powder Infant Fomula.Best baby formula for reflux: Enfamil A.R. Infant Formula.Best baby formula for gas: Enfamil Gentlease Infant Formula.Best baby formula for constipation: Enfamil Reguline Infant Formula.

2. Which milk is best for colic?

Goat milk formula is being anecdotally recommended by families who have switched their baby to goat milk based formula and seen an improvement in their baby's colic symptoms. This may have something to do with the fact that there is no added whey in the formula and it also has a lower lactose content.

3. Should I change formula if baby has colic?

Switching from a cow's milk formula to a hydrolyzed formula that's gentler on a baby's tummy has been recommended by the American Academy of Pediatrics for babies with colic. The AAP said parents could try a two-week trial of hydrolyzed formula to see if the gentler formula helps calm their baby.

4. Can babies get colic from formula?

Bottle feeding too fast (less than 20 minutes) or giving too much formula can trigger colic episodes.

Editor's Notes

During our baby formula for colic research, we found 24 baby formula for colic products and shortlisted 10 quality products. We collected and analyzed 89,496 customer reviews through our big data system to write the baby formula for colic list. We found that most customers choose baby formula for colic with an average price of $31.48.

The baby formula for colic are available for purchase. We have researched hundreds of brands and picked the top brands of baby formula for colic, including Similac, Enfamil, Good Start, Nutramigen, NUTRICIA PEPTICATE. The seller of top 1 product has received honest feedback from 385 consumers with an average rating of 4.7.

Written by
Elisa Drew Avatar

Elisa Drew is a really professional copywriter specializing in baby products with five years of experience working as a pediatrician once. She has published a series of baby books purchased by over thirty thousand people in the United States.