Best USB Serial Cables of 2025

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USB serial cables are an essential tool for connecting devices that use serial communication protocols to a computer or other device. These cables are designed to provide a reliable and fast connection between devices, allowing for data transfer and communication between them. With their compact size and plug-and-play functionality, USB serial cables are a convenient and versatile solution for a wide range of applications, including industrial automation, medical devices, and consumer electronics. Whether you need to connect a printer, scanner, or other device to your computer, or you need to transfer data between two devices, USB serial cables are an excellent choice.
At a Glance: Our Top Picks
Top 10 USB Serial Cables
SABRENT USB to Serial Converter Cable
The SABRENT USB to Serial Converter Cable provides a simple connection between USB and traditional RS-232 serial port for Windows, Mac, and Linux users. It supports various operating systems including Windows 11/10/8.1/8/7/VISTA/XP, Mac OS X 10.6 and Above, and Linux 2.4 or above. The adapter is easy to set up, simply plug your device into the adapter and the adapter into your PC or Mac. You can modify COM ports and Baud rates to your desired setup, providing flexibility and convenience.
CableCreation USB to RS232 Adapter
The CableCreation USB to RS232 Adapter is a 6.6ft USB 2.0 Male to RS232 Female DB9 Serial Converter Cable that connects devices such as modems, scanners, and digital cameras to a USB port on your computer. It features the latest Prolific PL2303 chipset and supports various operating systems including Windows, Linux, and Mac OS X. This adapter is easy to connect and is compatible with a wide range of devices with DB9 serial ports. It is USB bus powered, eliminating the need for an external power adapter.
TRENDnet USB to Serial Converter Cable
The TRENDnet USB to Serial Converter Cable allows you to connect RS-232 serial devices, such as modems and printers, to a USB 2.0 port. The flexible 21-inch cable accommodates most installation scenarios, and it supports USB 1.1, 2.0, and 3.0 ports. It is compatible with Windows and Mac operating systems, and it offers easy setup with plug-and-play functionality.
UGREEN USB to RS232 Adapter Serial Cable
This USB to RS232 adapter connects serial devices via USB port and is widely used in shopping malls and offices. It is compatible with Win 7 8 10 Win XP Vista Mac OS Linux system and suitable for connecting various RS232 serial devices such as cash registers, scanners, printers, and more. The double shielding layer isolates interference and its baud rate supports 20bps to 256kbps. Equipped with a powerful PL2303 chip, it can transmit signals at high speed and stably, protecting your data safely without loss.
CableCreation USB to RS232 Serial Cable
The CableCreation USB to RS232 Serial Cable connects serial DB9 devices such as a modem to a USB port on your computer. It features a USB port with 1Mbps data transfer rate, latest Prolific PL2303 chipset, easy connectivity, premium material and does not require an external power adapter. It works with modems, digital cameras, PDA, CNC, POS, bar code scanner and other devices with DB9 serial ports. Please note it is not compatible with Cutting Plotter or SCM.
Cable Matters USB to RJ45 Serial Console Cable
The Cable Matters USB Console Cable is a convenient solution for configuring networking switches and routers. With its USB port and RJ45 console port compatibility, it allows you to connect new computers and laptops without a serial port. The snagless male to male design protects the tab from being torn off and stuck in the console port. Installation is simple with the included FTDI drivers and instructions. This USB cable is compatible with Windows, Mac, and Linux, making it versatile for various systems. It also features a USB rollover cable that directly connects to routers, switches, servers, or wireless access points for easy configuration from the console port. With the Cable Matters USB Console Cable, you can program equipment without the need for a network or internet connection.
EVISWIY PL2303TA USB to TTL Serial Cable
The EVISWIY PL2303TA USB to TTL Serial Cable is an easy way to connect to microcontrollers, Raspberry Pi, and WiFi routers. With a built-in PL2303TA chipset, it supports a wide range of OSes, including Linux, and can be configured for either v5 or v3.3 power output. The four wires, including red, black, green, and white, make setup a breeze. Widely used for laboratories, product testing, and low cost MCU communications.
CableCreation USB Console Cable - 6 FT
The CableCreation USB Console Cable is a practical serial cable that connects a computer or laptop through USB port to Network Switch, Router, or other devices with console port. It is powered by USB port and supports Windows, Mac, Linux, and Android. The flat and slim flexible cable is easy to store and the gold plated connector ensures durability and fast data transmission.
C2G USB to DB9 RS232 Serial Adapter Cable
The C2G USB to DB9 RS232 Serial Adapter Cable allows you to connect DB9 devices to a PC without serial ports, making it ideal for devices like PDAs and digital cameras. The USB-A male to DB9 male cable offers a data transfer rate of over 230 kbps, ensuring fast and reliable data transfer.
Cable Matters USB to Serial Adapter
The Cable Matters USB Serial Cable makes it easy to connect your computer’s USB-A port to devices with a female DB9 port. This means you can quickly configure or program your equipment without hassle. Setting it up is straightforward, thanks to downloadable drivers, ensuring you spend less time troubleshooting. It’s also compatible with a wide range of Windows and Mac operating systems, which allows you to use it with various devices. If you encounter incompatible ports, a simple DB9 mini gender changer can help you connect effortlessly.
Frequently Asked Questions (FAQs)
1. What is USB serial cable?
The U209-000-R USB-to-Serial Adapter Cable allows you to connect a 9-pin RS-232 serial device to a computer or laptop with a USB Type-A port. It works with modems, digital cameras, PDAs, ISDN terminals and other devices with a serial port.
2. Are all USB to serial cables the same?
A standard port connection uses a DB-9 pin male or female serial connector. Other industrial type USB serial adapters may use an RJ-45 connector for data signal communication. You'll also need to look at your USB port; newer computers can contain a USB Type-C port for a host connection.
3. What cable is used for serial port?
What kind of cable do I need for a serial port connection between two computers? For the type of connection we are talking about here, you need a so called 'null modem cable'. A null modem cable is an RS-232 serial cable where the transmit and receive lines are crosslinked.
4. Can I use USB for serial communication?
Sabrent SBT-USC1K USB to Serial CableSTARTECH USBPlugable USB to Serial AdapterC2G USB to DB9 Serial Adapter Cable 26886StarTech.com ICUSB2321X USBTRENDnet TU-S9 USB to Serial ConverterStarTech USB DB9 DB25 RS232CableCreation USB to RS232 AdapterSabrent 6ft USB 2.0 to Serial DB-9 RS-232 Adapter Cable CB-FTDIKeyspan USA-19HS Tripp Lite High Speed USB to Serial AdapterStarTech.com USB C to Serial Adapter Cable RS232 DB9 (ICUSB232C)Sabrent USB 2.0 To Serial DB-9 RS-232 Converter CableAdafruit Industries 954 Usb-to-ttl Serial CableStarTech USB RS232 DB9 AdapterStarTech.com ICUSB232PROC USB C to Serial Adapter with Com RetentionC2G 5ft Trulink USB to DB9 Male Serial Adapter Cable 26887Startech.com 6' Professional Rs422/485 USB Serial Cable Adapter with COM Retention, Size: 6 feet, BlackUSB to RS232 Serial Adapter, CableCreation USB to DB9 Female Converter CableDTECH Serial Cable to USB Adapter DB9 Male RS232 Port Supports Windows 10 8 7 Mac
During our usb serial cable research, we found 24 usb serial cable products and shortlisted 10 quality products. We collected and analyzed 116,658 customer reviews through our big data system to write the usb serial cables list. We found that most customers choose usb serial cables with an average price of $15.19.
The usb serial cables are available for purchase. We have researched hundreds of brands and picked the top brands of usb serial cables, including SABRENT, CableCreation, TRENDnet, UGREEN, Cable Matters. The seller of top 1 product has received honest feedback from 1,833 consumers with an average rating of 4.9.

Mike Davis is a professionally trained electrician with six years of working experience in the electronics industry. He has written an array of web and mobile-based articles for e-magazines and blogs. He loves trying out some novel and popular gadgets and his expertise is in the areas of electronics and computers which is built over many years of working and personal experiences.