Best Serum Scalp Treatments of 2025

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Serum scalp treatments are gaining popularity among people who want to improve the health of their hair and scalp. These treatments typically come in small bottles with a dropper, and are applied directly to the scalp. They contain a concentrated formula of nourishing ingredients such as vitamins, minerals, and essential oils that work to stimulate hair growth, reduce inflammation, and moisturize the scalp. Some serum scalp treatments are also designed to combat dandruff and other scalp conditions. These treatments are easy to use and can be incorporated into any hair care routine for optimal results.
At a Glance: Our Top Picks
Top 10 Serum Scalp Treatments
Pacifica Beauty Scalp Serum, Rosemary Mint Scented
Experience the gentle yet effective detox and hydration of Pacifica Beauty Scalp Love Rosemary Mint Serum. Infused with natural ingredients like rosemary, witch hazel, sage, and thyme, this vegan and cruelty-free serum purifies and revives your scalp while moisturizing it. Enjoy the refreshing rosemary mint scent that soothes dry and flaky scalps without leaving behind an oily residue. Apply 2 to 4 droppers and massage into your scalp; use it as an overnight treatment or shampoo after use. Free from harsh chemicals like parabens, phthalates, SLS, mineral oil, and petrolatum, this sulfate-free serum is a weekly must-have for all skin types, whether oily or dry.
Dove Density Boost Serum
Dove Density Boost is designed to enhance the fullness and strength of your hair. Within just 30 days, you can see a noticeable increase in thickness and volume, making your hair look healthier and more vibrant. This serum not only promotes denser hair but also serves as a treatment for dry scalp, providing hydration where it's needed most. Developed with dermatologists, its lightweight formula absorbs quickly without leaving a greasy residue. Infused with essential vitamins and peptides, it nourishes your scalp for optimal hair growth and health.
Head & Shoulders Supreme Scalp Serum
Head & Shoulders Supreme Scalp Serum is a hydrating scalp treatment that deeply refreshes and renews your skin's surface in between washes. With regular use, it provides a healthy foundation for beautiful hair growth from the scalp. Whenever you experience itchiness or irritation, simply add a few drops of this serum to your scalp for instant relief. Infused with vitamin E and argan oil, this dry scalp treatment nourishes and moisturizes your scalp, promoting overall scalp health. The fresh-smelling formula is dye-free and adds a soothing experience to your day. With Head & Shoulders Supreme Scalp Serum, you can maintain a healthy and refreshed scalp effortlessly.
Jupiter Anti-Dandruff Scalp Serum
Jupiter Anti-Dandruff Scalp Serum is a perfect medicated leave-on restoring treatment for dry, itchy, and oily scalp. It is a vegan, cruelty-free, and sulfate-free product that helps relieve itching, flaking, irritation, and redness. The serum is formulated with Zinc Pyrithione, Aloe Vera, Salicylic Acid, and Green Tea that help soothe and moisturize your scalp, gently exfoliate your scalp, and revitalize your scalp. You can apply it directly to your scalp up to 4x per day. It's perfect for all hair types and safe for color and chemically-treated hair.
DERMA-E Scalp Relief Treatment
DERMA-E Scalp Relief Treatment is a powerful water-based serum that provides soothing relief for itchy scalps. It calms and nourishes the scalp, promoting repair and leaving it balanced and healthy. With the cooling properties of Menthol and Tea Tree Oil, this serum provides instant relief from itching. Aloe Vera moisturizes dry skin, reducing flakiness and irritation. The natural formula of this treatment includes Sea Kelp and Amla Extract, which deeply moisturize, and a proprietary Herbal Blend with Neem, Burdock, and Bearberry, which hydrates the scalp. For best results, apply after washing and before styling. Simply part your hair into sections and apply a few drops to each section, massaging it into the scalp. DERMA-E Scalp Relief Treatment is a clean beauty product that is 100% vegan and cruelty-free, and it does not contain any harmful ingredients.
Dermeleve Scalp Serum for Itch Relief
The Dermeleve Scalp Serum is designed to provide fast relief from itchy scalp conditions. Its easy application method allows you to dispense just the right amount directly onto your scalp, ensuring you avoid greasy hair. This steroid-free formula offers immediate and lasting relief from itchiness associated with conditions like neuropathic itch and scalp psoriasis. With its clear, non-greasy texture, you can use it as often as needed without worrying about unwanted residue. Additionally, the serum is hypoallergenic and safe for all skin types, making it ideal for those with sensitive skin.
Nioxin Scalp Recovery Soothing Serum
The Nioxin Scalp Recovery Soothing Serum is a luxury beauty product that helps with itchy, flaky scalps and dandruff. The serum contains pyrithione zinc and comes in a 3.38 oz bottle. The product is made in the United States and falls under the category of scalp treatments.
Renpure Apple Cider Vinegar Scalp Serum
The Renpure Apple Cider Vinegar Scalp Serum is a natural peppermint oil-based product designed to clarify and shine your scalp. It features apple cider vinegar to rebalance your scalp and remove flakes, leaving your hair refreshed and conditioned. The scalp serum uses plant-based conditioning nutrients, working in synergy with the scalp scrub, to give your scalp a fresh finish and add clarity and shine to your hair. Renpure is known for its gentle and nourishing formulas, using carefully chosen ingredients like tea tree oil, argan oil, shea butter, and coconut. This scalp serum is part of the Renpure Collection, which offers a range of responsibly sourced and ethically produced products for gentle cleansing from head to toe. With its plant-based beauty approach, this serum is free from sulfates, parabens, dyes, gluten, phthalates, propylene glycol, and bad vibes.
SEEN Restore Scalp Serum
SEEN Scalp Serum is a fragrance-free treatment that hydrates and soothes your scalp, reducing dryness, flakes, and irritation. It supports a healthy scalp barrier, absorbs quickly, and is not greasy. It is safe for all skin types, including sensitive, eczema-prone, and acne-prone skin. This non-comedogenic serum is formulated without harmful ingredients like fragrances, sulfates, and parabens, making it gentle and effective for scalp health.
MY BLACK IS BEAUTIFUL Cooling Scalp Serum
MBIB Scalp Serum is a dandruff treatment that relieves scalp dryness and itch associated with dandruff. It refreshes your scalp between wash days, making it perfect for protective styles like braids and twists. The Cooling Mint & Vitamin B3 in this serum provides a minty, cooling sensation that revitalizes your scalp, giving you a refreshing experience. With no sulfates or parabens, this scalp treatment is gentle on your hair.
Frequently Asked Questions (FAQs)
1. Are scalp serums good for hair?
By moisturizing the scalp with scalp serums for hair moisture, you can create an environment for healthy hair growth and more hydrated strands. Many people also use scalp serum for hair loss because scalp serums create a healthier environment for healthy hair to grow and stay put.
2. Do scalp serums work?
If hair serums contain ingredients that moisturize the scalp and increase blood flow to the scalp, they can significantly improve the condition of the scalp. So, a hair serum will not increase hair growth, but it may encourage producing follicles to grow thicker, shinier hair.
3. What is the use of scalp serum?
Scalp serums are meant to hydrate the skin beneath your hair, making them an increasingly popular solution for dry scalps. While a serum for your scalp may provide similar benefits to other hair treatments and scalp moisturizers already in your routine, the difference is, they're made with concentrated ingredients.
During our serum scalp treatment research, we found 48 serum scalp treatment products and shortlisted 10 quality products. We collected and analyzed 54,320 customer reviews through our big data system to write the serum scalp treatments list. We found that most customers choose serum scalp treatments with an average price of $14.29.
The serum scalp treatments are available for purchase. We have researched hundreds of brands and picked the top brands of serum scalp treatments, including Pacifica, Dove, Head & Shoulders, Jupiter, Derma E. The seller of top 1 product has received honest feedback from 385 consumers with an average rating of 4.7.

Lisa Bechard is a skin therapist with 12 years of working experience in the beauty industry and also an experienced beauty writer who has expertise in skincare, medical aesthetics and cosmetic surgery, and wellness. Her writing skills are excellent and all her content is very persuasive and insightful.