Best Stain Resistant Mattress Protectors of 2026

The BEDLORE Mattress Protector is designed to keep your mattress safe and comfortable. With its unique quilted top, it provides support while reducing heat and moisture buildup. The 100% waterproof layer effectively shields against spills, sweat, and other accidents, making it ideal for households with kids or elderly individuals. Its soft and noiseless microfiber material ensures a peaceful sleep, while the deep pocket design fits snugly on mattresses up to 18 inches deep, preventing any shifting during the night. This protector not only enhances your sleeping experience but also keeps your mattress clean and dry.

The Utopia Bedding Premium Waterproof Terry Mattress Protector is designed to fit Twin size mattress with dimensions 39 inches by 75 inches by 15 inches. It features a soft blended surface that is extra absorbent, cozy and breathable. The waterproof top and high-quality seam construction stops liquids from passing through the mattress. The fitted style all-around elastic band creates a secure fit on mattress depths. The mattress protector protects your mattress from unwelcome spills, keeping your mattress clean and safe. It is machine washable and can be tumble dried on low.

Protect your investment with the PlushDeluxe Mattress Protector! Made from natural bamboo fabric, this ultra-soft and breathable mattress cover safeguards your mattress from dirt, water, and normal wear and tear. The waterproof and breathable membrane resists water, including accidental spills and bodily fluids, making it an excellent choice for potty training, nursing sick kids, or having pets in your home. It fits all types of mattresses including memory foam, latex, or spring, and produces no crinkling sound. With a 10-year warranty, you can trust this mattress protector to keep your mattress fresh and clean for years to come.

Protect your mattress from fluids and moisture with the SafeRest Mattress Protector. Its noiseless, breathable, and wrinkle-free surface with membrane back coating ensures you sleep in silence without any disturbance. You won't even feel the soft cotton terry material, which maintains the original feel of your mattress. Suitable for all ages, this bedding essential is perfect for college dorm rooms, new homes, or first apartments.

The Springspirit Waterproof Protector is designed for ultimate comfort and protection. Its ultra-soft terry fabric feels gentle against your skin, while the waterproof backing safeguards your mattress from spills and stains, making it ideal for families with children or pets. The strong elastic ensures a snug fit on various mattress sizes, so you won’t have to worry about it slipping off. Plus, it’s machine washable, allowing for easy maintenance. Having a couple of these protectors on hand means you’ll always have a clean option ready when accidents happen.

The Premium Waterproof Mattress Protector with Bamboo Fiber Surface is designed to keep your mattress safe from spills and stains. The eco-friendly and natural bamboo fiber surface is cooling, skin-friendly, and good at wicking away moisture. The 100% waterproof back is made of premium TPU, which allows for breathability and noiseless protection. The 3D Air Fabric is soft, comfortable, and highly breathable, making your bed more comfortable. With an 18" deep pocket, it fits all types of mattresses up to 21" and prevents unwanted movement. Customer service is available, with a 30-day return/replacement service. For frequent accidents, we recommend purchasing multiple protectors to ensure a quick and easy swap.

The Amazon Basics Mattress Protector offers reliable waterproof protection to keep your mattress safe from spills and moisture, helping you maintain a clean and dry sleeping surface. Made with hypoallergenic cotton-terry material, it provides a comfortable and allergy-friendly option for a restful night's sleep. Its breathable design allows air to circulate, so you stay cool and comfortable without noise disruption. Plus, the fitted-sheet style fits mattresses up to 18 inches deep, ensuring a secure and snug fit that won’t shift during the night. This protector combines convenience with comfort for everyday use.

The MUXHOMO Waterproof Mattress Cover offers a breathable design made from bamboo rayon and polyester, helping you stay cool and comfortable throughout the night by evenly distributing heat. Its advanced waterproof layer protects your mattress from sweat, spills, and stains, giving you peace of mind against accidents. The cover is also quiet and soft, thanks to bamboo-derived viscose, so you won’t hear any crinkling noises as you move. Plus, its deep, stretchable pockets fit mattresses from 8 to 21 inches thick, including memory foam and latex, ensuring a snug fit that stays in place without slipping. This makes it a convenient and reliable choice for a better night’s sleep.

The Linenspa Waterproof Smooth Top Premium Queen Mattress Protector is designed to keep your mattress surface safe and fresh. The fitted-sheet-style mattress protector is made of flexible, vinyl-free fabric that fits up to 14” mattresses. It is 100% waterproof and safeguards your mattress against liquids, spills, and accidents. The smooth brushed polyester finish on the bed protector is soft, breathable and noiseless, allowing a peaceful night's sleep that won't change the feel of your mattress. The mattress protector is machine washable and dryer safe on low heat, making it an easy clean.

The DMI Waterproof Mattress Protector and Mattress Cover is a durable, waterproof pad that encases the entire mattress with a zipper closure, protecting against bedwetting, pet dander, spills, and more. The deep pockets keep it securely in place and the dependable material will not crack, peel, or discolor over time.