Best Insect Bite Treatments of 2026

Bonnie Salem Avatar
Bonnie Salem
Last Updated: Jan 16, 2026

* We independently evaluate all recommended products and services. If you click on links we provide, we may receive compensation.

Insect bite treatments are essential to alleviate the discomfort and itching caused by mosquito, flea, and tick bites. A variety of products are available over-the-counter, including creams, gels, and sprays that contain antihistamines, hydrocortisone, or calamine. These products work by reducing inflammation, itching, and swelling around the bite area. For those who prefer natural remedies, essential oils, aloe vera, and baking soda may also provide relief. It is important to seek medical attention if the bite area becomes infected or if the individual experiences severe allergic reactions such as difficulty breathing or swelling of the face and throat.

At a Glance: Our Top Picks

TENA Benadryl Anti Itch Gel Cover #TOP 1
TENA Benadryl Anti Itch Gel
ftb score rating icon 9.9
Hyland's PRID Drawing Salve, 18g Cover #TOP 2
Hyland's PRID Drawing Salve, 18g
ftb score rating icon 9.8
TENA Benadryl Anti-Itch Cream Cover #TOP 3
TENA Benadryl Anti-Itch Cream
ftb score rating icon 9.6

Top 10 Insect Bite Treatments

TENA Benadryl Anti Itch Gel

312547171571 1/9
White
TENA Benadryl Anti Itch Gel Cover
Benadryl Extra Strength Anti Itch Relief Gel, 2% Diphenhydramine HCl, Relief from Insect Bites, Sunburn & More, Great for Camping Essentials, 3.5 fl oz

Benadryl Anti Itch Gel is an effective solution for relieving discomfort from insect bites, minor burns, sunburn, and skin irritations. This topical gel contains 2% diphenhydramine hydrochloride, providing quick relief from itching and minor pain. You can easily carry it with you for immediate cooling relief whenever you need it, whether at home or outdoors. It’s particularly beneficial for treating rashes caused by poison ivy, helping to dry oozing and soothe irritation. Suitable for both adults and children over two years old, it’s a must-have for outdoor activities like camping and hiking.

What We Like
Fast-acting itch relief
Cooling, soothing sensation
Non-greasy, clear gel
Long-lasting effect
Convenient for travel
What We Don't Like
Occasionally runny texture
Slight tackiness before drying
#TOP 2

Hyland's PRID Drawing Salve, 18g

PRIDU18GM
Orange
Hyland's PRID Drawing Salve, 18g Cover
Hyland's PRID Drawing Salve, Topical Skin Irritation Relief, For Splinters, Thorns, Ingrown Hairs, Itch Relief for Bug Bites, Boils, Minor Cuts and Scrapes, 18 Grams

Hyland's PRID Drawing Salve offers fast relief for common skin problems like boils, minor rashes, redness, and small cuts or scratches. When you apply it to the affected area, it helps reduce pain and irritation, making you feel more comfortable quickly. The salve is easy to use—just apply it as needed to soothe your skin. This product is made with natural ingredients, so it’s gentle on your skin and safe to use without worrying about drug interactions. If you’re looking for a simple and natural way to calm minor skin irritations, Hyland's PRID Drawing Salve is a reliable choice.

What We Like
Effective for skin irritations
Draws out splinters, cysts, glass
Natural and gentle ingredients
Reduces pain and swelling
Affordable and travel-friendly tin
What We Don't Like
Unpleasant smell
Possible fabric staining
#TOP 3

TENA Benadryl Anti-Itch Cream

White
1 Fl Oz
TENA Benadryl Anti-Itch Cream Cover
Benadryl Extra Strength Itch Stopping Cream, Topical Analgesic Cream with Diphenhydramine HCl & Zinc Acetate Skin Protectant, Anti-Itch Ointment for Insect Bite & Sunburn Relief, 1 oz

Benadryl Anti-Itch Cream is designed to provide quick relief from pain and itching caused by various outdoor irritations. Whether you've been bitten by insects, suffered a minor burn, or are dealing with sunburn, this cream has you covered. It features a cooling formula that soothes discomfort and can help dry up the oozing from poison ivy and similar plants. Suitable for both kids and adults, it's an essential item to keep on hand for outdoor adventures like camping or hiking, ensuring you can enjoy your time outside without the distraction of itchiness.

What We Like
Fast itch relief
Effective extra strength formula
Non-greasy texture
Trusted brand
Long-lasting protection
What We Don't Like
Occasional reapplication needed
#TOP 4

Quitch Mosquito Bite Itch Relief Patch

quitch
Multi-color
Quitch Mosquito Bite Itch Relief Patch Cover
Quitch Mosquito Bite Itch Relief Patch, After Bite Insect Bite Treatment, Anti Itch Cream Alternative, Insect Bite Relief, Cruise, Travel and Camping Essential for Kids

The Quitch Itch Relief Patch is designed to give you fast relief from mosquito bite itching using a special hydrocolloid base that absorbs irritants like mosquito saliva. This makes it easier for you to stop scratching and feel comfortable quickly. The patches are gentle and safe for kids, made with natural ingredients like aloe and witch hazel, so you can use them without worrying about harsh chemicals. They're also super easy to use — just peel and stick the patch wherever you need it. Their small, travel-friendly packaging makes them perfect to carry on camping trips, cruises, or any outdoor adventure to keep your family itch-free.

What We Like
Fast itch relief
Stays on overnight
Gentle, kid-safe ingredients
Speeds up healing
Easy to use
What We Don't Like
Adhesive could last longer
Relief not immediate for all
#TOP 5

Amazon Basics Medicated Calamine Anti-Itch Lotion 6 oz

Amazon Basics
Pink
6 Fl Oz (Pack of 1)
Amazon Basics Medicated Calamine Anti-Itch Lotion 6 oz Cover
Amazon Basics Medicated Calamine Anti-Itch Lotion, Analgesic Skin Protectant, 6 Fluid Ounce, 1-Pack (Previously Solimo) (New Formula)

The Amazon Basics Calamine Lotion comes in a convenient 6-ounce bottle, providing you with easy-to-use relief for itchy skin. This lotion helps soothe pain and itching, making it a handy solution for insect bites and minor skin irritations. It works well if you’re dealing with rashes caused by poison oak, ivy, or sumac, offering temporary comfort. Additionally, the lotion has a drying effect that helps reduce moisture on the skin, which can speed up healing and make you feel more comfortable. If you like other calamine lotions, this product offers a similar, reliable option for your skin care needs.

What We Like
Fast itch relief
Gentle on sensitive skin
Non-sticky formula
Minimal scent
Good value
What We Don't Like
May not eliminate rash
#TOP 6

Benadryl Extra Strength Itch Relief Stick

493570
Benadryl Extra Strength Itch Relief Stick Cover
Benadryl Extra Strength Anti-Itch Relief Stick, Bug Bite Itch Relief, Diphenhydramine HCl Topical Analgesic & Zinc Acetate Skin Protectant, Great for Camping Essentials, 0.47 fl oz

The Benadryl Itch Relief Stick offers quick relief from skin discomfort. It works immediately upon application, easing pain and itching from insect bites, sunburn, and minor skin irritations. This handy stick is also effective against rashes caused by poison ivy and similar plants, making it a versatile addition to your first-aid kit. With a blend of diphenhydramine HCI and zinc acetate, it not only blocks histamines but also protects the skin, ensuring you feel comfortable and cared for in any outdoor situation.

What We Like
Fast itch relief
Compact and portable
Easy, mess-free application
Effective for various insect bites
Long shelf life
What We Don't Like
Relief may require reapplication
#TOP 7

Benadryl Extra Strength Itch Cooling Spray

24052
Multi
2 Fl Oz (Pack of 1)
Benadryl Extra Strength Itch Cooling Spray Cover
Benadryl Extra Strength Itch Cooling Spray, Topical Analgesic Spray with Diphenhydramine HCI & Zinc Acetate Skin Protectant for Fast Relief from Insect Bites, Travel Size, 2 fl. oz

The Benadryl Itch Cooling Spray is a handy 2-ounce travel-sized spray designed for both adults and children aged 2 and up. It offers quick relief from various outdoor itches caused by insect bites, minor burns, sunburn, and skin irritations like poison ivy or oak. The formula contains 2% diphenhydramine hydrochloride, which helps reduce pain and itching, and 0.1% zinc acetate to protect the skin and dry oozing from rashes. You can safely apply this spray up to three or four times daily to soothe affected areas, making it a convenient solution to keep you comfortable during outdoor activities.

What We Like
Immediate itch relief
Cooling sensation
Effective for hives and rashes
Works well on bug bites
Reduces swelling
What We Don't Like
Awkward pump application
Dries slightly sticky
#TOP 8

BUG BITE THING Suction Tool - Poison Remover

BBT0001
White
1 Count (Pack of 1)
BUG BITE THING Suction Tool - Poison Remover Cover
BUG BITE THING Suction Tool - Bug Bites and Bee/Wasp Stings, Natural Insect Bite Relief, Chemical Free - White/Single

The BUG BITE THING Suction Tool is a natural insect bite relief product that removes insect venom, saliva, and other irritants left under the skin using suction. It stops the body from producing the reaction that causes itching and swelling. It works on various insect bites, including mosquitoes, bees, wasps, biting flies, no-see-ums, chiggers, sea lice, and more. The product is compact, lightweight, reusable, and easy to carry. It is clinically proven, kid-friendly, and offers a 100% guarantee.

What We Like
Immediate itch relief
Drug-free and chemical-free
Easy to use and portable
Effective for kids and adults
Reusable and travel-friendly
What We Don't Like
Works best on fresh bites
Cap may crack easily
#TOP 9

Cutter BiteMD Insect Bite Relief Stick

95614
Multicolor
Cutter BiteMD Insect Bite Relief Stick Cover
Cutter BiteMD Insect Bite Relief Stick, Analgesic And Antiseptic 0.5 Fl Oz (Pack of 1)

The Cutter BiteMD Insect Bite Relief Stick is a convenient pocket-sized stick applicator that provides fast pain relief and relieves itching from bites and stings caused by insects like mosquitoes, ticks, chiggers, and wasps. The 3-in-1 formula of this first aid antiseptic stick reduces the chance of infection and features a soft tip for controlled application. It is the perfect solution for hikers and travelers as it is easy to carry and provides precise application without any mess.

What We Like
Fast itch relief
Convenient applicator
Reduces redness and swelling
Works for multiple insect bites
Safe for kids
What We Don't Like
Temporary stickiness
May sting on open skin
#TOP 10

quitch Bug Bite Itch Relief Patch

quitch
QUITCHSTKR36
quitch Bug Bite Itch Relief Patch Cover
quitch Bug Bite Itch Relief Patch FSA Eligible, Summer Travel Essentials for Kids, Mosquito Anti Itch Cream Alternative, Summer Camp Essentials Itch Relief, Baby hydrocortisone Cream Alternative

The quitch Bug Bite Patch offers a natural and effective solution to soothe mosquito bites quickly. If you want fast relief without chemicals, this patch uses a special hydrocolloid base combined with aloe and witch hazel to calm itching naturally. It's perfect for families heading to summer camps or outdoor adventures, as it’s easy to apply and safe for kids of all ages. Plus, it’s approved for FSA and HSA spending, making it a convenient option for parents who want a medicine-free way to protect their little ones from irritating bug bites.

What We Like
Instant itch relief
Mess-free and portable
Long-lasting adhesion
Safe for kids
Nearly invisible on skin
What We Don't Like
Limited large patch sizes
May be difficult to remove
Buying Guide Image

Frequently Asked Questions (FAQs)

1. When should you worry about an insect bite?

You should be concerned about an insect bite if a large area around the bite becomes red and swollen (around 10cm or larger), if you have symptoms of a wound infection such as pus, increasing pain, swelling, or redness, or if you experience symptoms of a more widespread infection such as a high temperature, swollen glands, and flu-like symptoms.

2. What helps bug bites heal faster?

To help bug bites heal faster, you can try applying ice to decrease inflammation and swelling, using hydrocortisone cream to reduce inflammation, applying baking soda to dry out the bite and reduce inflammation, using oatmeal to soothe the skin, applying toothpaste, and using calamine lotion.

3. What are three signs of an infected bite?

Three signs of an infected bite include the presence of pus in or around the bite, swollen glands, and increased pain, swelling, and redness in and around the bite.

4. How do I figure out what bit me?

To determine what bit you, you can look for specific characteristics. For example, bedbug bites leave small red and itchy marks, bee stings cause a red skin bump with white around it, and flea bites often leave itchy welts on the skin, commonly found on the ankles and legs.

5. When should you get a bite checked out?

You should see a doctor if you have signs of a systemic infection such as chills or a fever, especially if the fever is above 100°F (37.7°C). It is also important to seek medical attention if your child has any signs of an infected bug bite or if you have signs of lymphangitis, such as red streaks extending from the bite.

6. What does an infected bite look like?

An infected bite may appear as a red or dark line extending from the bite, with discoloration and swelling around it. Sores or abscesses may also develop on or around the bite, along with swollen glands (lymph nodes).

7. What do spider bites look like?

Spider bites typically resemble other bug bites, appearing as red, inflamed, sometimes itchy or painful bumps on the skin. In most cases, harmless spider bites do not produce any other symptoms. However, it's important to note that many skin sores can look similar but have different causes, such as bacterial infections.

8. What bug bite leaves a hard lump?

Bites from midges, mosquitoes, and gnats often result in the formation of small itchy papules or lumps on the skin.

Editor's Notes

During our insect bite treatment research, we found 24 insect bite treatment products and shortlisted 10 quality products. We collected and analyzed 694,082 customer reviews through our big data system to write the insect bite treatments list. We found that most customers choose insect bite treatments with an average price of $6.71.

The insect bite treatments are available for purchase. We have researched hundreds of brands and picked the top brands of insect bite treatments, including Benadryl, Hyland's, quitch, BUG BITE THING, Cutter. The seller of top 1 product has received honest feedback from 384 consumers with an average rating of 4.7.

Written by
Bonnie Salem Avatar

Bonnie Salem is a stay-at-home mother with two-year-old twins and has spent almost half of her life surrounded by baby products. As a mother and a professional copywriter, she has an insightful and unique eye for researching products suitable for infants. Bonnie Salem is an expert in health and nutrition who lives with her family in New Jersey. She has over 15 years of working experience in an institute of medicine after graduating from the University of Toronto. She is highly interested in personal health and wellness.

Insect Bite Treatments Comparison Table

#TOP1
#TOP2
#TOP3
#TOP4
#TOP5
#TOP6
#TOP7
#TOP8
#TOP9
#TOP10
Brand Benadryl Hyland's Benadryl quitch Amazon Basics Benadryl Benadryl BUG BITE THING Cutter quitch
Product Benefits Allergy Control Irritant Drawing, Pain Relief Itch Control - Itch Control Anti-itch Relief,Itch Relief Itch Control - - Itch Control
Item dimensions L x W x H 1.47 x 2.43 x 6.35 inches 0.75 x 2.13 x 2.06 inches 9.06 x 4.88 x 1.19 inches - 2.11 x 2.11 x 5.55 inches - 1.24 x 1.75 x 4.62 inches - - 2.56 x 2.36 x 0.04 inches
Item Weight 4 ounces 0.04 Pounds - - 7.84 ounces 0.47 Ounces - - - 0.03 Ounces
Specific Uses For Product Allergy Insect Bite Relief, Minor cuts, Scrapes - - - Bladder Control See label - - Mosquito
FTB Score
ftb score rating icon 9.9
ftb score rating icon 9.8
ftb score rating icon 9.6
ftb score rating icon 9.4
ftb score rating icon 9.3
ftb score rating icon 9.2
ftb score rating icon 9.1
ftb score rating icon 9.0
ftb score rating icon 8.8
ftb score rating icon 8.6
Where to Buy