Best Electric Toothbrush Heads for Oral-B Pro 500 of 2026

Elisa Drew Avatar
Elisa Drew
Last Updated: Jan 16, 2026

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Electric toothbrush heads for the Oral-B Pro 500 are an essential accessory for maintaining optimal oral hygiene. These high-quality brush heads are designed to fit perfectly onto the Oral-B Pro 500 electric toothbrush, providing a superior clean that reaches all areas of the mouth. With advanced bristle technology and a round brush head, these toothbrush heads effectively remove plaque and prevent gum disease. The Oral-B Pro 500 electric toothbrush heads are easy to replace and come in a variety of styles for personalized brushing. Upgrade your oral care routine with these top-quality toothbrush heads for the Oral-B Pro 500.

At a Glance: Our Top Picks

GENKENT Replacement Toothbrush Heads Cover #TOP 1
GENKENT Replacement Toothbrush Heads
ftb score rating icon 9.8
20 Pcs Replacement Brush Heads for Oral-B Electric Toothbrush Cover #TOP 2
20 Pcs Replacement Brush Heads for Oral-B Electric Toothbrush
ftb score rating icon 9.7
Voguish Replacement Toothbrush Heads for Oral-B Cover #TOP 3
Voguish Replacement Toothbrush Heads for Oral-B
ftb score rating icon 9.5

Top 4 Electric Toothbrush Heads for Oral-B Pro 500

GENKENT Replacement Toothbrush Heads

12110586030
White
GENKENT Replacement Toothbrush Heads Cover
Replacement Toothbrush Heads Compatible with Oral B Braun, 12 Pcs Professional Electric Toothbrush Brush Heads Compatible with Oral B Replacement Heads Refill 7000/Pro 1000/9600/500/3000

GENKENT Brush Heads are a pack of 12 high-quality replacement toothbrush heads. With 4 color rings to distinguish them, these brush heads are perfect for sharing with your family. They are compatible with various Oral-B electric toothbrush models, except for a few specific ones. The soft and flexible Dupont bristles ensure a superior brushing experience, as they are durable and won't easily fall off. The advanced bristle system, with precise angled bristles, can reach deep between teeth and along the gum line, removing more plaque than a manual toothbrush. Installing and using these brush heads is easy and convenient. Simply pull off the old head and snap on the new one. With GENKENT Brush Heads, you can enjoy a thorough and effective cleaning every time.

What We Like
Affordable price
Perfect fit for Oral-B
Easy replacement process
Decent cleaning performance
Durable bristles
#TOP 2

20 Pcs Replacement Brush Heads for Oral-B Electric Toothbrush

12110586051
White - Adult
20 Pcs Replacement Brush Heads for Oral-B Electric Toothbrush Cover
Replacement Toothbrush Heads Compatible with Oral-B Braun, 20 Pcs Professional Electric Toothbrush Brush Heads for Oral B Replacement Head Refill Pro 500/1000/1500/3000/3757/5000/7000/7500/8000

Genkent offers a pack of 20 affordable and high-quality replacement brush heads compatible with most Oral-B electric toothbrush models, except Vitality Sonic, Sonic Complete, Pulsonic, CrossAction Power and iO. The brush heads are designed with soft and flexible Dupont bristles that are durable and not easy to fall off, ensuring a superior brushing experience. The precise angled bristles can reach deep between teeth and remove more plaque along the gum line and in between teeth than a manual toothbrush. With 4 different color rings, the brush heads can be distinguished among family members. The installation process is easy and smooth, and the replacement toothbrush head can be firmly fixed by pressing the head during installation.

What We Like
Cost-effective alternative
Good quality and performance
Compatible with Oral-B
Multiple replacements available
Soft bristles
#TOP 3

Voguish Replacement Toothbrush Heads for Oral-B

MK-09
White
1 Count (Pack of 4)
Voguish Replacement Toothbrush Heads for Oral-B Cover
Replacement Toothbrush Heads Compatible with Oral B Braun, 4 Pack Electric Toothbrush Heads Brush Heads Refill for Oral-B 7000/Pro 1000/9600/ 500/3000/8000

The Voguish Replacement Toothbrush Heads for Oral-B come in a pack of 4 with color rings to distinguish them. The extra soft bristles are gentle on sensitive and inflamed areas, removing plaque and defending against gingivitis. The toothbrush heads prevent cavities with side-to-side bristles and a moving power tip that penetrates hard-to-reach areas. They work with most Oral-B rechargeable handles and are easy to install, making them a great value purchase.

What We Like
Extra soft bristles for gentle cleaning around sensitive and inflamed areas
Prevents cavities with side-to-side bristles and a moving power tip
Compatible with most Oral-B rechargeable handles
#TOP 4

Replacement Heads Compatible with Braun Oral B Pro 1000, Genius X

MOFELE
EB50-8-BK
8 Black
1 Count (Pack of 8)
Replacement Heads Compatible with Braun Oral B Pro 1000, Genius X Cover
Replacement Heads Compatible with Braun Oral B Pro 1000, Genius X, Smart 1500 Electric Toothbrush, 8 Pcs Precision Brush Heads Refills Compatible with Oral B (Black)

Features
[All Round Cleaning] :Toothbrush Heads Compatible With Oral B Uses Different Diameters Of Cross-Flowering Technology, Multi-Angle Deep Into The Teeth, Strike Out The Plaque That Is Difficult To Remove Between The Teeth, To Make The Cleaning Without Dead Ends.
[Perfect Compatibility] : Compatible With Most Oral B Toothbrush Handles, Such As Pro 1000, Genius X, Smart 1500, Vitality, Triumph, Professional, Pro 500, 7000 SmartSeries, Pro 8000 And So On.
[Great Customer Service] :We Offer A Worry-Free 90-Day Warranty Window. If You Are Not Satisfied Or The Product Breaks, Just Send A Message To Let Us Know And We Will Contact You And Handle Your Problem In Time.
[Gentle And Effective Cleaning] : The Brush Head Compatible With Oral B Is Made Of High Quality Bristles, And The Top Of Bristle Is Rounded To Effectively Clean And Carefully Care For Your Teeth At The Same Time.
[Easy To Install, Easy To Replace] : To Better Clean Your Teeth, We Recommend That You Replace The Brush Head Every Three Months. Simply Pop Out The Old Head And Snap In The New One , It's Easy And Smooth.
Buying Guide Image

Frequently Asked Questions (FAQs)

1. Do Oral-B toothbrush heads fit all models?

All of the Oral-B brush heads will fit to and work with any of the current and many older Oral-B electric toothbrushes. They are designed to be interchangeable*. All brush heads work on any Oral-B brush handle and cleaning mode.

2. Do all Oral-B electric toothbrushes use the same heads?

With the exception of Pulsonic models, all Oral B brush heads work with all Oral B toothbrushes so you can interchange different heads. This means you can build multiple heads into your cleaning routine, depending on the type of cleaning action you want. Precision Clean is the original Oral B brush head.

3. What heads are compatible with Oral-B toothbrush?

Answer: The Precision Clean toothbrush head is compatible with all Oral-B electric toothbrush handles except Oral-B Sonic. It works with Oral-B Triumph, Oral-B SmartSeries, Oral-B PRO, Oral-B Vitality (except for Vitality Sonic) and Oral-B Pro Health Power except for Oral-B iO.

4. How do I know which Oral-B brush head I have?

It is a 4-digit number which can be found on the underside of your toothbrush and is highlighted by the red arrows below. The Type Number should also be listed on the user manual for your toothbrush.

Editor's Notes

During our electric toothbrush head for oral-b pro 500 research, we found 24 electric toothbrush head for oral-b pro 500 products and shortlisted 4 quality products. We collected and analyzed 799,681 customer reviews through our big data system to write the electric toothbrush heads for oral-b pro 500 list. We found that most customers choose electric toothbrush heads for oral-b pro 500 with an average price of $15.23.

The electric toothbrush heads for oral-b pro 500 are available for purchase. We have researched hundreds of brands and picked the top brands of electric toothbrush heads for oral-b pro 500, including GENKENT, Voguish, MOFELE. The seller of top 1 product has received honest feedback from 1,118 consumers with an average rating of 4.8.

Written by
Elisa Drew Avatar

Elisa Drew is a really professional copywriter specializing in baby products with five years of experience working as a pediatrician once. She has published a series of baby books purchased by over thirty thousand people in the United States.