Best Cat Relaxants of 2025

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Cat relaxants are a great way to help calm down anxious or stressed felines. These products come in various forms such as sprays, diffusers, and chews. They contain natural ingredients like pheromones, essential oils, and herbs that help soothe the cats' nerves and promote relaxation. Cat owners can use these products to help their pets cope with stressful situations such as traveling, vet visits, or introducing new pets to the household. These relaxants are safe and effective, and they can help improve the overall well-being of cats.
At a Glance: Our Top Picks
Top 10 Cat Relaxants
TopSum Calming Collar for Cats
The TopSum Cat Calming Collar is designed to help your feline friend manage anxiety and stress effectively. It starts working within minutes, making it ideal for cats that experience fear from loud noises or new environments. The collar is made from soft materials, ensuring comfort during extended wear. You can adjust the size for a snug fit, suitable for cats of all sizes, including kittens and larger breeds. Plus, its lightweight design makes it travel-friendly, helping to ease anxiety during car rides or vet visits.
Sentry Calming Chews for Cats
Sentry Calming Chews are designed to help your cat cope with stress during challenging times. Whether your feline friend faces daily stress or occasional triggers, these chews provide essential support. They are scientifically proven, developed in collaboration with experts, ensuring a safe and effective way to keep your cat calm. Understanding the needs of anxious cats, these chews help manage stress in a healthy manner. Plus, with a tasty crunchy exterior and a creamy center, your cat will enjoy these soothing bites while feeling more relaxed.
FELIWAY Optimum Enhanced Calming Pheromone Diffuser
FELIWAY Optimum is a drug-free solution to help reduce common signs of stress in cats. The heated diffuser covers up to 700 square feet and is supported by 25+ years of feline stress expertise. The starter kit includes 1 diffuser head and 1 vial. For best results, position the diffuser where your cat spends most of their time and replace the vial once a month.
EDUZEBRA Cat Melatonin Sleep Aid
EDUZEBRA Cat Melatonin is designed to help your cat relax and feel calm, addressing issues like irritability and anxiety. By promoting restful sleep, this gentle formula ensures your feline companion can enjoy uninterrupted nights, especially if they struggle with settling down. It's easy to use—simply mix the recommended dose into your cat's food or water, making it a hassle-free addition to their routine. This product not only supports your cat’s well-being but also contributes to a more peaceful environment for both you and your pet.
FELIWAY MultiCat Diffuser Starter Kit
FELIWAY MultiCat Diffuser Starter Kit is a vet recommended solution that helps reduce tension between cats at home. It mimics a mother cat's natural nursing pheromones to promote social contact and acceptance. By plugging in the diffuser with the vents facing up in your cat's favorite room, you can see improvements in behaviors like conflict, fighting, chasing, and blocking. With a refill needed monthly, this drug-free diffuser offers a convenient way to create a harmonious environment for your feline friends.
FELIWAY Optimum Refill
FELIWAY Calming Pheromone Refill is the ultimate solution to reduce stress in cats. It helps with common signs of stress like scratching, urine spraying, tension between cats, fears, and reactions to changes. This drug-free option has been rated highly by 93% of cat owners, with an average satisfaction rating of 9.1 out of 10. Backed by over 25 years of feline stress expertise, FELIWAY Calming Pheromone Refill covers up to 700 square feet and lasts for a month. Position the diffuser where your cat spends most of its time for optimal results.
TriOak 4 Pack Cat Calming Collar
The TriOak Cat Calming Collar offers a safe and effective way to reduce your cat's anxiety and stress. This collar works quickly, helping your cat feel relaxed in just minutes. With a convenient 4-pack, you can ensure your pet has a calming solution for up to 120 days, perfect for unexpected stressful situations. Made from soft materials, the collar is comfortable for your cat to wear all day without irritation. Plus, its adjustable size makes it suitable for cats of all shapes and sizes, ensuring a snug fit that allows your cat to move freely.
FELIWAY MultiCat Calming Pheromone Refill
FELIWAY MultiCat Refill is a vet-recommended solution that helps reduce tension between cats at home, such as conflicts and fighting. With an 84% success rate reported by cat owners, this drug-free diffuser mimics a mother cat's natural nursing pheromones to promote social bonding. By plugging in the diffuser correctly and placing it where your cat spends most of its time, you can create a harmonious environment for your feline friends. Each refill lasts up to a month, ensuring continuous calming effects.
Pet Honesty Calming Chews for Cats
Pet Honesty Cat Calming Chews are designed to help your feline friend relax during stressful situations. With a delightful chicken flavor and a unique texture, these chews are not only tasty but also easy for your cat to enjoy. They contain key ingredients like L-Theanine and Chamomile, which work together to soothe anxiety and promote a sense of calm. Additionally, they support overall nervous system health and help curb destructive behavior. By offering these chews, you can help your cat feel more comfortable during travel, vet visits, or any time they might feel anxious.
Comfort Zone Multi Cat Calming Diffuser Refills
Comfort Zone Cat Calming Refills by Comfort Zone offer a value pack with 6 refills lasting up to 6 months. You can reuse the diffuser for 12 months, replacing the refill for continuous calming. It helps reduce tension, fighting, and stress between cats, creating a relaxing environment. This drug-free solution calms cats, reducing unwanted behaviors like urine spraying and scratching. Veterinarian recommended, these refills come with a satisfaction guarantee, showing improved cat behavior in just 2 weeks.
During our cat relaxant research, we found 24 cat relaxant products and shortlisted 10 quality products. We collected and analyzed 396,394 customer reviews through our big data system to write the cat relaxants list. We found that most customers choose cat relaxants with an average price of $22.55.
The cat relaxants are available for purchase. We have researched hundreds of brands and picked the top brands of cat relaxants, including TopSum, Sentry, FELIWAY, EDUZEBRA, TriOak. The seller of top 1 product has received honest feedback from 238 consumers with an average rating of 4.9.

Janie Foster is a writer & pet blogger from Los Angeles, she enjoys living with her two cats and three dogs. She owned her first dog 10 years ago and then started her personal blog to record her dog's daily life. Throughout her personal life, she has developed specialized knowledge in pet care, pet nutrition, feeding habits, and more.
Cat Relaxants Comparison Table
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Brand | TopSum | Sentry | FELIWAY | EDUZEBRA | FELIWAY | FELIWAY | TriOak | FELIWAY | Pet Honesty | Comfort Zone |
Brand Name | TopSum | Sentry | FELIWAY | EDUZEBRA | FELIWAY | FELIWAY | TriOak | FELIWAY | Pet Honesty | Comfort Zone |
Target Audience Keyword | house-cats | house-cats, Cats | house-cats, Cats | house-cats | house-cats | house-cats, cats | house-cats | house-cats | house-cats | house-cats |
Age Range Description | All Life Stages | Adult | All Life Stages | All Life Stages | All Life Stages | All Life Stages | All life stages | All ages | All Ages | All Life Stages |
Specific Uses for Product | cat | Behavior | Behavior | Active | Behavior | Behavior | cats | Behavior | Calming | Behavior |
Directions | Read instructon manual for more details | DIRECTIONS FOR USE: For use in cats 12 weeks and older. Give 1 chew per 1 lb of weight daily or as needed. Do not exceed the recommended daily amount in a 24-hour period. | FELIWAY Optimum heated diffuser and refill provide calming pheromones continually for up to 30 days in a 700 square foot area. We recommend using an additional diffuser if the room is bigger than 700 square feet. We recommend plugging in the FELIWAY Optimum diffuser in the room where you cat spends the most time. Try not to plug the diffuser under items (e.g. shelves) or close to objects (e.g. behind curtain or doors) as this affects efficacy. We do not recommend plugging your diffuser in near your litterbox or in a hallway - your cat likely does not spend as much time in the places as you'd think. Use FELIWAY Optimum each month to create a constant calming environment. Check the diffuser monthly and replace it twice a year (every six months) to guarantee the best effect. Do not use another plugin with FELIWAY Optimum refills. Do not use FELIWAY diffuser with another refill of another brand. Make sure you are using a FELIWAY Optimum diffuser with your FELIWAY Optimum vials and refills. Each FELIWAY Diffuser comes with a plug adapted to the local electric systems. Please do not use this diffuser in a another country that has a different voltage or with an adapter: it may conduct serious security concerns. Make sure that your diffuser has the fitting plug for your country before plugging in. | for cats | Replace Every 30 Days. Plug the diffuser in with the vents facing up, and avoid placing the diffuser under shelves and behind doors, curtains, or furniture: for the best results, place in the room(s) where your cat spends most of his or her time. To maximize effectiveness, replace the vial once a month, and the diffuser every 6 months. | FELIWAY Optimum refills provide calming pheromones continually for up to 30 days in a 700 square foot area. We recommend using an additional diffuser if the room is bigger than 700 square feet. We recommend plugging in the FELIWAY Optimum diffuser in the room where you cat spends the most time. Try not to plug the diffuser under items (e.g. shelves) or close to objects (e.g. behind curtain or doors) as this affects efficacy. We do not recommend plugging your diffuser in near your litterbox or in a hallway - your cat likely does not spend as much time in the places as you'd think. Use FELIWAY Optimum each month to create a constant calming environment for your cat. Each refill will last up to 30 days - we recommend replacing your refills on a monthly basis. Check the diffuser monthly and replace it twice a year (every six months) to guarantee the best effect. Do not use another plugin with FELIWAY Optimum refills. Additionally, do not use a FELIWAY Optimum diffuser with a refill of another brand. Make sure you are using a FELIWAY Optimum diffuser with your FELIWAY Optimum vials and refills. Each FELIWAY Optimum Diffuser comes with a plug adapted to the local electric systems. Please do not use this diffuser in a another country that has a different voltage or with an adapter: it may conduct serious security concerns. Make sure that your diffuser has the fitting plug for your country before plugging in. | see manual | Replace Every 30 Days | Give 1 chew per 1 lb of body weight. Begin with half the suggested amount, and gradually increase to the suggested daily amount. Amounts can be split between AM and PM. | - |
Model Name | New2024 | Calming Chews for Cats | Feliway Optimum | me1959 | Feliway MultiCat Diffuser Starter Kit Constant Harmony & Calming Between Cats at Home | Feliway Optimum | New24 | Feliway Animal Health Multicat Feliway Refill (3 Pack) | - | Multicat Calming Diffuser Refill, 48 ml- 6 Pack, 180 Day Use |
Item Weight | - | 4 ounces | 4.8 ounces | 3.2 ounces | 5.6 ounces | 1.6 ounces | 2.39 ounces | 7.2 ounces | 3.7 ounces | 10.9 ounces |
Item Package Dimensions L x W x H | - | 7.87 x 5.47 x 1.13 inches | 6.38 x 4.65 x 2.8 inches | 4.29 x 1.46 x 1.42 inches | 6.14 x 4.61 x 3.7 inches | 4.61 x 2.05 x 2.01 inches | 5.87 x 4.76 x 0.75 inches | 4.02 x 3.7 x 3.5 inches | 6.88 x 4.54 x 1.34 inches | 10.43 x 3.78 x 3.62 inches |
Color | Gray | Brown | Translucent | transparent | clear | Translucent | Light Purple | Basic | - | - |
Size | - | 4 Oz | 1 Pack | - | 1.62 Fl Oz (Pack of 1) | 1 pack | - | 3 Count (Pack of 1) | 30 Count (Pack of 1) | 6-Pack |
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