Best Bus-Powered Audio Interfaces of 2025

The Focusrite Clarett+ 2Pre USB-C Audio Interface is designed to produce high-quality recordings with its professional-grade preamps, all-analogue Air, improved A-D and D-A converters, and JFET instrument inputs. The USB-C connection provides bus power and the improved headphone output ensures flat frequency response at all output levels with any type of headphones. The software for PC, Mac and iOS devices gives complete control over all aspects of Clarett+.

The Antelope Zen Quadro offers exceptional audio quality with high-fidelity conversion, ensuring your recordings sound clear and professional. With four discrete preamps providing 75dB gain, you can capture every detail of your performance, whether it's vocals or instruments. The real-time DSP+FPGA processing feature allows you to track and monitor with nearly no latency, giving you the ability to enjoy authentic vintage tones in your mixes. Additionally, the interface includes 37 vintage-inspired effects, adding warmth and character to your projects, making it an ideal choice for audio professionals seeking creativity and precision.

The PreSonus USB Audio Interface is a value-packed 2-channel USB 2.0 interface that is perfect for personal and portable recording. With its high-quality Class-A mic preamps, you can easily achieve a great sound. It also features high-headroom instrument inputs, allowing you to record guitar, bass, and other line-level devices, as well as MIDI I/O. The studio-grade converters support up to 24-bit/96 kHz recording and playback, ensuring professional-level audio quality. Plus, it comes with over $1000 worth of recording software, including Studio One Artist, Ableton Live Lite, and the Studio Magic Plug-In suite. The USB bus-power makes it mobile friendly, and the onboard mixer control allows you to monitor with zero latency. With its high-powered headphone output and balanced ¼” TRS outputs, this audio interface is a versatile and convenient tool for any recording setup. The +48V phantom power accommodates studio condenser microphones, making it suitable for a wide range of recording applications.

The SSL 2+ MKII Interface is perfect for producers, podcasters, and live musicians. It features two XLR mic preamps and additional line inputs, making it easy for you to connect various audio sources. With its high-quality 32-bit/192 kHz AD/DA converters, you can expect exceptional sound clarity. The device also includes zero-latency monitoring, allowing you to hear your recordings in real-time without delays. Plus, the stereo loopback function is great for streaming or recording sessions, as it lets you capture audio from multiple sources simultaneously.

The Antelope Audio Zen Q Synergy Core USB-C Audio Interface offers professional sound and stability with its highly efficient AD/DA converter chips and proprietary 64-bit AFC. It features 2 ultra-linear preamps designed with authentic console circuitry for classic warmth and sonic depth, and 2 additional analog inputs with switchable Hi-Z/Line modes. The interface also provides real-time, low latency processing of 37 included analog-modeled Synergy Core effects with 50+ optional expansions, and flexible I/O connectivity with 8 additional inputs over ADAT and stereo I/O over S/PDIF.

The SSL 2 MKII Interface is an excellent choice for producers, podcasters, and musicians. It features two XLR mic preamps, allowing you to connect professional microphones for high-quality recordings. With two 1/4" line inputs and Hi-Z options, you can easily plug in instruments or other audio sources. The interface also offers 48V phantom power and zero-latency monitoring, ensuring that you can hear yourself in real-time without any delay. Additionally, the stereo loopback feature is perfect for live streaming or recording sessions, simplifying the process of capturing your audio.

The PreSonus AudioBox USB is a powerful audio and MIDI interface designed for musicians and recording enthusiasts. It connects easily through USB, making it convenient for both Mac and Windows users. With its 24-bit resolution and multiple sampling rates, you can achieve high-quality sound for your recordings. The interface features two combo mic/instrument inputs, allowing you to connect various audio sources while ensuring low noise and high performance. Plus, the 48V phantom power provides the necessary boost for condenser microphones, enhancing your recording capabilities.

The Universal Audio Volt 276 is your all-in-one solution for creating music, livestreams, and podcasts on various devices like Mac, PC, iPad, and iPhone. You can achieve rich, full sound by utilizing the Vintage Mic Preamp mode when recording vocals and instruments. The 76 Compressor adds clarity to your audio, reminiscent of the renowned 1176 model. Along with these features, you’ll have access to top-tier software, including Ableton and Melodyne, making your production process seamless and professional.

The Arturia MiniFuse 2 is a versatile audio and MIDI interface designed for musicians, producers, and podcasters. With USB Type-C connectivity, you can easily connect your devices for seamless audio transfer. It features two mic/line/instrument preamps, allowing you to record vocals and instruments with clarity. The headphone output ensures you can monitor your sound in real-time, while the stereo monitor output provides a professional listening experience. Plus, the 24-bit/192 kHz converters deliver high-quality audio, making it ideal for both home studios and on-the-go recording.

The CAD Audio Interface is designed for seamless audio recording with its impressive 24 Bit/96KHz resolution, ensuring high-quality sound for your projects. You can easily power it using USB, making it a convenient choice for mobile setups. With +48V phantom power, you can connect condenser microphones, enhancing your recording options. Best of all, this interface is plug-and-play, meaning you won’t need to install any drivers, allowing you to focus on your creativity without technical hassles. Plus, it works well with various recording software on both Windows and Mac systems.