Best Medical Skin Protectants & Barrier Creams of 2026

Brian Howie Avatar
Brian Howie
Last Updated: Aug 30, 2023

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Are you looking for the medical skin protectants & barrier creams from different brands on the market, such as Smith & Nephew, 3M, Medline, Ensur, Decon Labs, but don't know where to start? To help you find the top 7 Best Medical Skin Protectants & Barrier Creams that meet different needs, we have carefully researched a large amount of medical skin protectants & barrier creams.

Based on our extensive evaluations of testing dozens of medical skin protectants & barrier creams in different price ranges from $9.00 to $159.00, we have concluded this list of the best medical skin protectants & barrier creams. We picked Smith & Nephew Medical Skin Protectants & Barrier Cream as our preferred option. Read on for a list of our top picks, as well as a buying guide on how to select.

At a Glance: Our Top Picks

Smith and Nephew SECURA Protective Ointment Skin Protectant, 5.6 Ounce (Pack of 2) Cover #TOP 1
Smith and Nephew SECURA Protective Ointment Skin Protectant, 5.6 Ounce (Pack of 2)
ftb score rating icon 9.8
3M Health Care 3346 Cavilon No Sting Barrier Film, Pump Spray Bottle, 28 mL Capacity (Pack of 12) Cover #TOP 2
3M Health Care 3346 Cavilon No Sting Barrier Film, Pump Spray Bottle, 28 mL Capacity (Pack of 12)
ftb score rating icon 9.7
Medline Skintegrity Hydrogel Wound Dressing, 12 Count, 4 Ounce Cover #TOP 3
Medline Skintegrity Hydrogel Wound Dressing, 12 Count, 4 Ounce
ftb score rating icon 9.5

Top 7 Medical Skin Protectants & Barrier Creams

#TOP 1

Smith and Nephew SECURA Protective Ointment Skin Protectant, 5.6 Ounce (Pack of 2)

TM80665
Smith and Nephew SECURA Protective Ointment Skin Protectant, 5.6 Ounce (Pack of 2) Cover
Smith and Nephew SECURA Protective Ointment Skin Protectant, 5.6 Ounce (Pack of 2)

Features
Clove Oil Helps Mask Odor
Contains 98% Petrolatum
Vitamins A, D And E To Soothe And Condition Sensitive Skin
Pediatrician Tested
#TOP 2

3M Health Care 3346 Cavilon No Sting Barrier Film, Pump Spray Bottle, 28 mL Capacity (Pack of 12)

3M
3346
3M Health Care 3346 Cavilon No Sting Barrier Film, Pump Spray Bottle, 28 mL Capacity (Pack of 12) Cover
3M Health Care 3346 Cavilon No Sting Barrier Film, Pump Spray Bottle, 28 mL Capacity (Pack of 12)

Features
The Intelligent Choice To Help Prevent Medical Adhesive-Related Skin Injury (MARSI) Around Infusion Sites And Wounds: CHG Compatible
More Clinical Evidence Than Any Other Moisture Barrier Or Barrier Film
Will Not Clog Or Reduce Absorbency Of Diapers Or Pads
Helps Protect Skin Around Wounds And Ostomies From Moisture And Body Fluids
#TOP 3

Medline Skintegrity Hydrogel Wound Dressing, 12 Count, 4 Ounce

MSC6104
4 Ounce
Medline Skintegrity Hydrogel Wound Dressing, 12 Count, 4 Ounce Cover
Medline Skintegrity Hydrogel Wound Dressing, 12 Count, 4 Ounce

Features
Contains Glycerin As A Humectant To Remain Moist And Viscous And Aloe
Donates Moisture To Create An Optimal Moist Wound Healing Environment
Ideal For Dry-To-Moist Clean Wounds
Helps Create A Moist Wound Environment
Easily Irrigated From The Wound At Dressing Change
Balanced Formulation
Available In Squeezable Bellows Bottle For Convenient, Targeted Application
#TOP 4

DermaPhor Skin Protectant 4 Ounce Tube Unscented Ointment, 00184 - Sold by: Pack of ONE

00184
3.75 Ounce
DermaPhor Skin Protectant 4 Ounce Tube Unscented Ointment, 00184 - Sold by: Pack of ONE Cover
DermaPhor Skin Protectant 4 Ounce Tube Unscented Ointment, 00184 - Sold by: Pack of ONE

Features
White Petrolatum
White Petrolatum
Unscented
Ointment
#TOP 5

Decon Labs 9503 Proguard Professional Handcream (Pack of 12)

9503
Decon Labs 9503 Proguard Professional Handcream (Pack of 12) Cover
Decon Labs 9503 Proguard Professional Handcream (Pack of 12)

Features
Package Weight: 3 Pounds
Package Dimensions: 7 L X 4.25 H X 6 W (inches)
Part Number: 9503
Country Of Origin : United States
#TOP 6

StingFree Skin Prep Spray Bottle, 2 oz

00236
2 Ounce
StingFree Skin Prep Spray Bottle, 2 oz Cover
StingFree Skin Prep Spray Bottle, 2 oz.

Features
Will Not Clog Diapers Or Interfere With Absorbent Pads
Provides Up To 72-Hours Of Protection
To Protect Against Excessive Moisture Due To Wound Exudate, Tube Drainage Or Incontinence
To Prevent Skin Stripping From Adhesives
To Decrease Friction Damage Over Bony Prominences
#TOP 7

Selan Barrier Cream with Zinc Oxide - 4oz Tube (Each/1) by Span America

80841400
Selan Barrier Cream with Zinc Oxide - 4oz Tube (Each/1) by Span America Cover
Selan Barrier Cream with Zinc Oxide - 4oz Tube (Each/1) by Span America

Features
Span America 80841400 SELAN+ With Zinc Oxide - 4 Oz Tube - 1 Each
Buying Guide Image
Editor's Notes

During our medical skin protectants & barrier cream research, we found 7 medical skin protectants & barrier cream products and shortlisted 7 quality products. We collected and analyzed 1,843 customer reviews through our big data system to write the medical skin protectants & barrier creams list. We found that most customers choose medical skin protectants & barrier creams with an average price of $52.94.

The medical skin protectants & barrier creams are available for purchase. We have researched hundreds of brands and picked the top brands of medical skin protectants & barrier creams, including Smith & Nephew, 3M, Medline, Ensur, Decon Labs. The seller of top 1 product has received honest feedback from 17,053 consumers with an average rating of 4.9.

Written by
Brian Howie Avatar

Brian Howie is a content writer and senior industrial designer. After graduation from Westminster College, he has been engaged in product design and manufacturing for 18 years. Brian Howie has always found great pleasure in designing industrial products and sharing his ideas and experience online.