Best Benzalkonium Chloride Hand Soap of 2026

Lisa Bechard Avatar
Lisa Bechard
Last Updated: Jan 13, 2026

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Benzalkonium Chloride Hand Soap is a highly effective and popular hand soap that is commonly used in healthcare settings, food service establishments, and other industries where cleanliness and hygiene are of utmost importance. This soap is known for its powerful disinfecting properties, which help to kill germs and bacteria on contact. It is also gentle on the skin, making it a great choice for those with sensitive skin or allergies. Benzalkonium Chloride Hand Soap is available in a variety of formulations, including foaming and non-foaming, and can be used in both commercial and residential settings.

At a Glance: Our Top Picks

Spa Sense Antibacterial Hand Soap Cover #TOP 1
Spa Sense Antibacterial Hand Soap
ftb score rating icon 9.9
Provon Antimicrobial Lotion Soap 4 Oz Cover #TOP 2
Provon Antimicrobial Lotion Soap 4 Oz
ftb score rating icon 9.8
Zep Commercial Antimicrobial Hand Soap, 1 Gallon, R46124, 128 Fl Oz (Pack of 1) Cover #TOP 3
Zep Commercial Antimicrobial Hand Soap, 1 Gallon, R46124, 128 Fl Oz (Pack of 1)
ftb score rating icon 9.6

Top 10 Benzalkonium Chloride Hand Soap

#TOP 1

Spa Sense Antibacterial Hand Soap

SS1601
Spa Sense Antibacterial Hand Soap Cover
Spa Sense Antibacterial Hand Soap with Aloe Vera - Kills 99.99% of Germs - Non-Drying, Hydrating, Conditioning - Rich, Creamy, and Nourishing Hand Wash, 16 Ounce, Unscented

Spa Sense Hand Soap is a soothing antibacterial cleanser designed to keep your hands germ-free while providing hydration. Its rich, creamy lather effectively removes dirt, grease, and grime without drying out your skin. The key ingredient, Benzalkonium Chloride, ensures that 99.99% of common germs are eliminated, making it a reliable choice for your home. This eco-conscious formula is gentle and nourishing, allowing you to enjoy a luxurious handwashing experience that leaves your skin feeling clean and cared for.

What We Like
Non-drying formula
Hydrating and conditioning
Effective germ protection
Earth-conscious ingredients

Provon Antimicrobial Lotion Soap 4 Oz

SG_B00BHU3ULS_US
4 Fl Oz (Pack of 1)
Provon Antimicrobial Lotion Soap 4 Oz Cover
Provon Antimicrobial Lotion Soap - 4 Oz

Provon Antimicrobial Soap is designed to keep your hands clean while being gentle on your skin. Its creamy lather helps wash away germs effectively without causing dryness, ensuring your hands feel soft and moisturized. You can enjoy all-day freshness with its odor protection feature, which keeps you feeling clean throughout your busy day. The soap's hydrating formula rinses away easily, striking the perfect balance between cleanliness and moisture. This makes it an excellent choice for daily use, so you can maintain healthy skin while combating germs.

What We Like
Moisturizing formula
Odor protection
Creamy lather
Easy rinsing

Zep Commercial Antimicrobial Hand Soap, 1 Gallon, R46124, 128 Fl Oz (Pack of 1)

Zep
R46124
Zep Commercial Antimicrobial Hand Soap, 1 Gallon, R46124, 128 Fl Oz (Pack of 1) Cover
Zep Commercial Antimicrobial Hand Soap, 1 Gallon, R46124, 128 Fl Oz (Pack of 1)

Zep Antimicrobial Hand Soap is a gentle formula that encourages frequent use. It does not use harsh alkalis, abrasives or solvents, making it perfect for those with sensitive skin. The mild solution prevents drying skin and the clean-rinsing design prevents leaving sticky residue on hands. This soap is perfect for use in any setting, whether it be at home or in a commercial environment. With its gentle formula, Zep Antimicrobial Hand Soap is a great choice for anyone looking for a reliable and effective hand soap.

What We Like
Gentle formula
Mild solution
Clean-rinsing design
#TOP 4

Dial Professional Gold Antibacterial Liquid Hand Soap

88047EA
Gold
Dial Professional Gold Antibacterial Liquid Hand Soap Cover
Dial Professional Gold Antibacterial Liquid Hand Soap, 1 Gallon Refill Bottle, 128 Fl Oz

Dial Professional Gold Antibacterial Liquid Hand Soap is a mild and effective hand soap that helps remove dirt, residue, and bacteria from hands. The 1-gallon refill bottle makes it convenient to refill smaller containers. It contains skin conditioners that keep your hands soft and supple. It is effective against various bacteria, yeast, and mold. Moreover, it is biodegradable and comes in recyclable packaging.

What We Like
Mild and effective hand soap
Contains skin conditioners for soft and supple hands
Effective against various bacteria, yeast, and mold
1-gallon refill bottle for convenient use
Biodegradable and uses recyclable packaging
#TOP 5

McKesson Antibacterial Liquid Hand Soap

53-28067-18
1 Count (Pack of 1)
McKesson Antibacterial Liquid Hand Soap Cover
McKesson Antibacterial Liquid Hand Soap, 18 oz [Pack of 1] Pump Bottle, Clean Scent

Features
To Reduce Bacteria On The Skin, It Contains Benzethonium Chloride (0.13); Gentle Formulation Gently Cleans And Moisturizes Skin, And The Clean Scent Keeps Your Hands Feeling Fresh
Daily Protecting Benzethonium Chloride Soap Guards Against A Host Of Germs; To Properly Clean Hands, A Dense And Rich Lather Is Formed When Used
Gentle And Mild On Your Hands With A pH-Balanced Formula; Liquid Comes In Light Orange Color
Comes In An 18 Ounce Pump Bottle With A Screw-Top Cap For Quick And Convenient Usage; Aids In The Reduction Of Any Cross-Contamination; For Easy Use
Clean Scent And Rich In Lather To Throoughly Clean Hands
#TOP 6

Dial Antibacterial Defense Liquid Hand Soap + Aloe

00017000209463
Dial Antibacterial Defense Liquid Hand Soap + Aloe Cover
Dial Antibacterial Defense Liquid Hand Soap + Aloe, Aloe Scent, 11 Fl Oz (Pack of 12), Dermatologist-Tested Hand Wash, Gentle Formula

Features
Tough On Bacteria, Gentle On Skin: From The #1 Dr Recommended Brand,* This Liquid Hand Soap Rinses Clean Without Leaving A Residue. Dermatologist-Tested & pH Balanced, Suitable For All Skin Types *Antibacterial Hand Soap
Gentle Formula: Dial Up Your Handwashing Routine With This Antibacterial Liquid Hand Soap That Kills More Than 99.9% Of Bacteria* And Creates A Luxurious Lather. Cleanses Deep While Being Gentle On Skin. *Encountered In Household Settings
With Moisturizers: Dial Formulas Are Created With Conditioners & Gentle Cleansers, Giving You A Balanced Clean. Formulated With Aloe Vera, This Liquid Hand Soap Removes Dirt And Impurities And Leaves Skin Feeling Thoroughly Clean And Soft
Vegan Hand Soap: Made Without SLS/SLES, Parabens, Phthalate & Silicones. Approved As Cruelty Free Under The Leaping Bunny Program. Bottle Made With 100% Recycled Plastic (pump Excluded) Sodium Lauryl Sulfate/Sodium Laureth Sulfate
User-Friendly For Every Sink: Whether At The Kitchen Sink, Bathroom Counter, Or In Shared Spaces, Dial Hand Soap Is Great For High-Traffic Areas
Leaves Skin Feeling Clean: As One Of The Founding American Personal Cleansing Brands, Dial Became A Household Name In The 1940s. Today, Dial Continues To Innovate Across Body Wash, Bar And Hand Soap To Help You, And Your Family, Dial Up Your Clean
#TOP 7

Clorox 16 oz Antibacterial Hand Soap

BB16742
Soothing Aloe
Clorox 16 oz Antibacterial Hand Soap Cover
Clorox Antibacterial Liquid Hand Soap with Pump, Soothing Aloe Scent - Scented Hand Wash, Liquid Soap for Bathroom or Kitchen - Washes Away Dirt from Hands and Keeps Them Soft, 16 Fl Oz

Clorox Antibacterial Hand Soap is designed to keep your hands clean while being gentle on your skin. With its powerful formula, it effectively eliminates 99.99% of germs, giving you peace of mind every time you wash your hands. The soothing aloe scent adds a refreshing touch, making handwashing a pleasant experience. You’ll appreciate how easy it is to use—just pump a small amount onto wet hands, lather for 30 seconds, and rinse. This 16 oz bottle is perfectly sized for your kitchen or bathroom, ensuring you have just the right amount of soap when you need it.

What We Like
Effective germ elimination
Soothing aloe scent
Gentle on skin
Easy to use
Perfect bottle size
#TOP 8

McKesson Antibacterial Liquid Hand Soap

53-28067-18
Light Orange
McKesson Antibacterial Liquid Hand Soap Cover
McKesson Antibacterial Liquid Hand Soap, 18 oz [Pack of 12] Pump Bottle, Clean Scent

Features
To Reduce Bacteria On The Skin, It Contains Benzethonium Chloride (0.13); Gentle Formulation Gently Cleans And Moisturizes Skin, And The Clean Scent Keeps Your Hands Feeling Fresh
Daily Protecting Benzethonium Chloride Soap Guards Against A Host Of Germs; To Properly Clean Hands, A Dense And Rich Lather Is Formed When Used
Gentle And Mild On Your Hands With A pH-Balanced Formula; Liquid Comes In Light Orange Color
Comes In An 18 Ounce Pump Bottle With A Screw-Top Cap For Quick And Convenient Usage; Aids In The Reduction Of Any Cross-Contamination; For Easy Use
Clean Scent And Rich In Lather To Throoughly Clean Hands
#TOP 9

McKesson Antibacterial Liquid Hand Soap

53-28061-GL
Light Orange
McKesson Antibacterial Liquid Hand Soap Cover
McKesson Antibacterial Liquid Hand Soap, 1 Gallon [Pack of 1] Refill, Clean Scent

Features
To Reduce Bacteria On The Skin, It Contains Benzethonium Chloride (0.13); Gentle Formulation Gently Cleans And Moisturizes Skin, And The Clean Scent Keeps Your Hands Feeling Fresh
Daily Protecting Benzethonium Chloride Soap Guards Against A Host Of Germs; To Properly Clean Hands, A Dense And Rich Lather Is Formed When Used
Hand Wash Lathers Up Softly And Richly, Leaving A Fresh Scent Behind
Gentle And Mild On Your Hands With A pH-Balanced Formula; Liquid Comes In Light Orange Color
Comes In 1 Gallon Jar With A Screw-Top Cap For Quick And Convenient Usage; Aids In The Reduction Of Any Cross-Contamination; For Easy Use, Transfer The Liquid Into A Smaller Bottle
#TOP 10

CLn® HandWash - Advanced Hygiene

CLn
CLN-HW-240ml-FBM
Clear
8 Fl Oz (Pack of 1)
CLn® HandWash - Advanced Hygiene Cover
CLn® HandWash - Advanced Hygiene for Hands, Formulated with Glycerin, for Sensitive Skin Prone to Hand Dermatitis, Redness, Irritation, Eczema, and Rash, Fragrance-Free, 8 fl oz

Features
Mild Yet Effective Formula: Patented Combination Of Sodium Hypochlorite And USP-Grade Glycerin For Additional Hydration Unlike The Drying Effects Of Alcohol Sanitizers.
Developed By Physicians: Clinically Proven Formula Is Gentle, Yet Effective To Help With Compromised Hands Prone To Itching And Flaking Caused By Frequent Hand Washing, Dryness, And Irritation.
Non-Drying: Can Be Used Often Without Over-Drying Or Disrupting The Skin Barrier, Making It Ideal For Those Who Come In Contact With Bacteria On A Daily Basis Like Health Care Professionals.
How To Use: Wet Hands And Lather HandWash Over The Backs Of Your Hands, Your Palms, Between Your Fingers And Under Your Nails. Massage For 30-60 Seconds. Rinse Thoroughly Under Running Water.
Fragrance-Free, Paraben-Free AndHypoallergenic: Formulated Without Common Irritants, This Cleanser Is Free Of Parabens, SLS, Triclosan, And Fragrances. Not Tested On Animals.
2025 Beauty Innovation Award Hand Product Of The Year.
Buying Guide Image

Frequently Asked Questions (FAQs)

1. Is benzalkonium chloride safe in soap?

There are three main ingredients currently being used in antibacterial soap: benzalkonium chloride, benzelthonium chloride and chloroxylenol. The FDA has noted that there is a lack of evidence as to the safety and effectiveness of these ingredients. As of now, the FDA has not banned these ingredients.

2. What is benzalkonium chloride in hand soap for?

What is Benzalkonium Chloride? This ingredient is commonly used as a surfactant and antibacterial agent, and is commonly found in household cleaning products. Benzethonium Chloride has replaced Triclosan as the new “antibacterial” agent in cosmetic and commercial soaps and santizers.

3. Is benzalkonium chloride safe on skin?

This cosmetic ingredient is not a sensitizer to normal humans at concentrations of 0.1%, but may be to individuals with diseased skin. It is concluded that Benzalkonium Chloride can be safely used as an antimicrobial agent at concentrations up to 0.1%.

Editor's Notes

During our benzalkonium chloride hand soap research, we found 23 benzalkonium chloride hand soap products and shortlisted 10 quality products. We collected and analyzed 162,879 customer reviews through our big data system to write the benzalkonium chloride hand soap list. We found that most customers choose benzalkonium chloride hand soap with an average price of $15.56.

The benzalkonium chloride hand soap are available for purchase. We have researched hundreds of brands and picked the top brands of benzalkonium chloride hand soap, including Spa Sense, unitedtattoosupply, Zep, Dial, McKesson. The seller of top 1 product has received honest feedback from 1,695 consumers with an average rating of 4.9.

Written by
Lisa Bechard Avatar

Lisa Bechard is a skin therapist with 12 years of working experience in the beauty industry and also an experienced beauty writer who has expertise in skincare, medical aesthetics and cosmetic surgery, and wellness. Her writing skills are excellent and all her content is very persuasive and insightful.