Best Genetic Tests of 2025

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Genetic tests are a type of medical test that examines a person's DNA to determine if they have any genetic mutations or predispositions to certain diseases. These tests can provide valuable information about a person's health and help them make more informed decisions about their lifestyle and medical care. Genetic tests can also be used to identify inherited conditions in families and help individuals understand their risk of passing on these conditions to their children. While genetic testing can be a powerful tool, it is important for individuals to understand the limitations and potential risks of these tests before undergoing them.
At a Glance: Our Top Picks
Top 10 Genetic Tests
23andMe Ancestry + Traits Service DNA Test Kit
Discover your ancestry to the 0.1% across 2000+ geographic regions with the 23andMe Ancestry + Traits Service DNA Test Kit. Opt-in to DNA Relative Finder to connect with people who share your DNA, and automatically build your family tree. Get personalized trait reports from 30+ reports that uncover how your genes make you unique. The process is simple and easy, all from home with no blood or needles required. Your data is encrypted, protected, and under your control.
AncestryDNA Genetic Test Kit
AncestryDNA Test Kit offers a unique DNA experience by revealing your origins in over 2,600 global regions and connecting you with living relatives. With a 3-month "World Explorer" membership, access billions of family history records. By combining DNA results with an Ancestry subscription, you can build your family tree and explore millions of family trees and records online. Get precise ethnicity estimates with detailed geographic information and see matches by parental side using SideView technology. Your data is protected with industry-standard security measures.
23andMe Health + Ancestry Service
Discover more about your health and ancestry with the 23andMe Health + Ancestry Service. This at-home DNA test kit provides personalized genetic insights and tools that can help you make informed decisions about your health. The health features include reports on your genetic predispositions to certain health conditions, wellness insights based on your DNA, and carrier status reports for inherited health conditions. The simple and easy testing process involves collecting a saliva sample using the provided kit and sending it back to the lab. Your data is private and protected, ensuring that you are in control of what you want to learn and share.
AncestryDNA + Traits Test
Discover your DNA story with AncestryDNA + Traits Test by following a few simple steps. In roughly six to eight weeks, you can explore how your genes might have influenced a range of appearance, sensory, fitness, nutrient, and other personal characteristics with 35+ of your most interesting traits. You can also get a more precise ethnicity estimate with greater geographic detail and in-depth historical insights that connects you to the places in the world where your story started. With an Ancestry subscription, you can combine what you learn from your DNA with over 100 million family trees and billions of records for more insight into your genealogy and origins. When you send in your DNA test kit, Ancestry employs industry-standard security measures in all stages of the process, work to protect your data, and give you control over it—with data encryption, secure databases, and easy-to-use controls.
AncestryDNA Genetic Ethnicity Test
Discover your DNA story and ancestry with AncestryDNA Genetic Ethnicity Test. In a few simple steps, activate your DNA kit online and send the sample to the lab for analysis. Get an ethnicity estimate with greater geographic detail, in-depth historical insights, and side view technology to show the ethnicities passed down from each parent. Combine the DNA results with an Ancestry subscription for access to millions of family trees and billions of records, and build your own family tree. AncestryDNA protects your privacy with industry-standard security measures and secure databases.
23andMe Health-only Service DNA Test
23andMe Health DNA Test provides more than 65 personalized reports on your health and wellness. Discover insights into your genetic predispositions, carrier status for inherited conditions, and how your DNA can influence lifestyle factors like diet and exercise. Your data is kept private and secure, giving you control over what you learn and share. By opting in to research, you contribute to scientific discoveries that could impact global health.
empowerDX MTHFR Gene Test Kit
empowerDX Gene Test Kit allows you to check for variants of the MTHFR gene at home. The MTHFR gene affects folate processing in your body, impacting mental health, fertility, and more. Using a simple mouth swab, you can discover if you have certain gene variants linked to mental health issues, fertility problems, and other conditions. The test results, available securely online, come with a guide for easy understanding. empowerDX Gene Test Kit offers convenience and privacy in exploring your genetic makeup.
LifeDNA Methylation Genes Test Kit
The LifeDNA Gene Test Kit allows you to analyze 12 different gene variants, including MTHFR and COMT, to gain insights into your genetic health. It's designed for easy at-home testing, letting you collect your DNA sample with a simple cheek swab. Your results are processed in accredited laboratories in the USA, ensuring high-quality analysis. Plus, you can review your findings with a LifeDNA expert, who can help you understand how your genes may affect your energy and mood. This comprehensive approach makes it simple to tailor your wellness strategy based on your unique genetic makeup.
Whole Genome Sequencing Kit by Sequencing
The Sequencing DNA Test Kit offers valuable insights into your health by analyzing your entire genome. This means you'll receive personalized recommendations to help reduce your disease risks and improve your overall wellness. Your privacy is a top priority, as the kit guarantees that your data remains yours, with no sharing or selling to third parties. Additionally, you will gain access to the latest advancements in genetic research, empowering you with up-to-date information. The user-friendly kit makes it easy to get started, ensuring that you can understand your genetic profile without any hassle.
tellmeGen Advanced DNA Test
The tellmeGen Advanced DNA Test offers 7 tests in 1, providing you with more than 400 reports on health predispositions, carrier status, pharmacogenetics, ancestry, wellness, and traits. With lifetime updates and personalized genetic reports, you can adapt your lifestyle and improve your well-being. Plus, your genetic data is private and protected with encrypted data, and you can take the test from home with just a saliva sample.
Frequently Asked Questions (FAQs)
1. What can be detected with genetic testing?
Genetic testing can detect various conditions, including Down syndrome, Huntington's disease, cystic fibrosis, sickle cell disease, phenylketonuria, colon (colorectal) cancer, and breast cancer. These tests analyze an individual's genetic makeup to identify specific genetic mutations or variations associated with these conditions.
2. What are 2 common types of genetic testing?
Two common types of genetic testing are molecular tests and chromosomal tests. Molecular tests examine changes in one or more genes, while chromosomal tests analyze whole chromosomes or long lengths of DNA to identify large-scale changes. Additionally, gene expression tests can determine which genes are turned on or off in different types of cells.
3. Is there a genetic test for Ehlers Danlos syndrome?
For rarer forms of Ehlers-Danlos syndrome, genetic tests on a blood sample can confirm the diagnosis and rule out other conditions. However, for the most common form, hypermobile Ehlers-Danlos syndrome, there is currently no genetic testing available.
4. What are 7 genetic disorders?
Some examples of genetic disorders include albinism, Angelman syndrome, ankylosing spondylitis, Apert syndrome, Charcot-Marie-Tooth disease, congenital adrenal hyperplasia, cystic fibrosis (CF), and Down syndrome. These disorders are caused by genetic mutations and can lead to various physical and intellectual disabilities.
5. What Cannot be detected in a genetic test?
Genetic testing can provide limited information about an inherited condition. It cannot determine if a person will show symptoms of a disorder, the severity of the symptoms, or the progression of the disorder over time. Other factors, such as environmental influences, can also play a role in the development and manifestation of genetic disorders.
6. What is the most common genetic testing?
Newborn screening is one of the most common uses of genetic testing. Almost every newborn in the U.S. undergoes genetic testing for several genetic diseases as part of early detection and intervention efforts. This widespread screening aims to identify potential genetic conditions early on to initiate appropriate medical care and support.
7. What is the most specific genetic test?
Genome sequencing is considered the most comprehensive and specific genetic test. It examines an individual's entire DNA sequence, providing detailed information about their genetic makeup. By analyzing all of a person's DNA, genome sequencing can identify specific genetic variants or mutations associated with various conditions or diseases.
8. Is Ehlers-Danlos inherited from mother or father?
Ehlers-Danlos syndrome can be inherited through autosomal recessive inheritance, specifically for kyphoscoliotic EDS. In this case, the faulty gene responsible for the condition is inherited from both parents. Each child of these parents has a 1 in 4 chance of developing the condition.
9. Can 23 and me detect Ehlers-Danlos?
Direct-to-consumer genetic testing services like 23andMe and Ancestry.com are not suitable for diagnosing Ehlers-Danlos syndrome or hypermobility spectrum disorder. These tests typically analyze a limited number of single nucleotide polymorphisms (SNPs) and do not provide information on pathogenic genetic variants associated with these conditions.
10. What are the top 10 most common genetic disorders?
Some of the top 10 most common genetic disorders include Down syndrome (Trisomy 21), Fragile X syndrome, Klinefelter syndrome, Triple-X syndrome, Turner syndrome, Trisomy 18, and Trisomy 13. These disorders result from genetic abnormalities and can lead to various physical and developmental challenges.
11. What are the top 5 most common genetic disorders?
Some of the top 5 most common genetic disorders include Down syndrome, thalassemia, cystic fibrosis, Tay-Sachs disease, and sickle cell anemia. These disorders are caused by genetic mutations and can have significant impacts on an individual's health and quality of life.
During our genetic test research, we found 24 genetic test products and shortlisted 10 quality products. We collected and analyzed 768,797 customer reviews through our big data system to write the genetic tests list. We found that most customers choose genetic tests with an average price of $134.81.
The genetic tests are available for purchase. We have researched hundreds of brands and picked the top brands of genetic tests, including 23andMe, AncestryDNA, empowerDX, LIFEDNA, Sequencing. The seller of top 1 product has received honest feedback from 159 consumers with an average rating of 4.7.

Elisa Drew is a really professional copywriter specializing in baby products with five years of experience working as a pediatrician once. She has published a series of baby books purchased by over thirty thousand people in the United States.