Best Disinfectant Wipes of 2025

Bonnie Salem Avatar
Bonnie Salem
Last Updated: Jan 6, 2025

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Disinfectant wipes are an essential item for any household, workplace or public setting. These wipes are designed to kill germs and bacteria on surfaces, making them an effective tool in preventing the spread of illnesses. They are easy to use and provide a quick and convenient solution for disinfecting frequently touched surfaces such as doorknobs, countertops, and electronic devices. Disinfectant wipes come in a variety of sizes and scents, making them a versatile and user-friendly product. Whether you are looking to keep your home or workplace clean and healthy, disinfectant wipes are a must-have item.

At a Glance: Our Top Picks

Amazon Basics Disinfecting Wipes, Lemon & Fresh Scent, 85 Count, Pack of 4 Cover #TOP 1
Amazon Basics Disinfecting Wipes, Lemon & Fresh Scent, 85 Count, Pack of 4
ftb score rating icon 9.8
Clorox Disinfecting Wipes, Multi-surface Wipes with Moisture Seal Lid Cover #TOP 2
Clorox Disinfecting Wipes, Multi-surface Wipes with Moisture Seal Lid
ftb score rating icon 9.7
Lysol Disinfectant Handi-Pack Wipes, 480 Count (Pack of 6) Cover #TOP 3
Lysol Disinfectant Handi-Pack Wipes, 480 Count (Pack of 6)
ftb score rating icon 9.5

Top 5 Disinfectant Wipes

#TOP 1 Best Value

Amazon Basics Disinfecting Wipes, Lemon & Fresh Scent, 85 Count, Pack of 4

Amazon Basics
89-300LLFF851J
White
Amazon Basics Disinfecting Wipes, Lemon & Fresh Scent, 85 Count, Pack of 4 Cover
Amazon Basics Disinfecting Wipes, Lemon & Fresh Scent, Sanitizes/Cleans/Disinfects/Deodorizes, 340 Count (4 Packs of 85)

Amazon Basics Disinfecting Wipes are now available in a new look and come with 10 more wipes per canister. The pack includes two canisters of Lemon Scent and two canisters of Fresh Scent, with a total of 340 disinfecting wipes. These thick wipes kill COVID-19, cold & flu virus, bacteria, E. coli, and Salmonella. They are versatile and can be used on various washable hard surfaces such as kitchen countertops, sinks, and toys, making them great for touch-up cleaning and tough messes.

What We Like
Kills COVID-19, cold & flu virus, bacteria, E. coli, and Salmonella
Thick wipes for touch-up cleaning and tough messes
Versatile, can be used on various washable hard surfaces
#TOP 2

Clorox Disinfecting Wipes, Multi-surface Wipes with Moisture Seal Lid

10044600600335
White
Clorox Disinfecting Wipes, Multi-surface Wipes with Moisture Seal Lid Cover
Clorox Disinfecting Wipes, Bleach Free Cleaning Wipes, Household Essentials, Fresh Scent, Moisture Seal Lid, 75 Wipes, Pack of 3 (New Packaging)

Clorox Disinfecting Wipes are all-in-one cleaning wipes that can kill 99.9% of viruses and bacteria, including COVID-19 in 15 seconds. The wipes come in a space-saving pack that is easy to stack and carry around. They can be used on various surfaces such as finished wood, sealed granite and stainless steel. The new easy-pull flip-top pack allows for the easiest way to clean and disinfect. The wipes are bleach-free, deodorize and sanitize everything from toys to car spills with their fresh scent.

What We Like
Kills 99.9% of viruses and bacteria including COVID-19 in 15 seconds
Multi-surface cleaner for various surfaces including finished wood, sealed granite and stainless steel
New easy pull-pack for easy cleaning and disinfecting
#TOP 3 Best For Travel

Lysol Disinfectant Handi-Pack Wipes, 480 Count (Pack of 6)

1920099716
White
Lysol Disinfectant Handi-Pack Wipes, 480 Count (Pack of 6) Cover
Lysol Disinfectant Handi-Pack Wipes, Multi-Surface Antibacterial Cleaning Wipes, for Disinfecting and Cleaning, Lemon and Lime Blossom, 480 Count (Pack of 6)

The Lysol Disinfectant Handi-Pack Wipes are multi-surface cleaning wipes that are 3x stronger than a paper towel. They can kill 99.9% of viruses and bacteria, including COVID-19 virus, on hard, non-porous surfaces. These wipes are perfect for tackling tough messes on various surfaces such as remotes, tablets, and smartphones. With a fresh scent of Lemon and Lime Blossom, these wipes also remove allergens like pet dander, dust mites, and pollen.

What We Like
Kills 99.9% of viruses and bacteria, including COVID-19 virus (when used as directed)
3x stronger than a paper towel
Suitable for multiple surfaces, including remotes, tablets, and smartphones
#TOP 4

PDI Super Sani-Cloth Surface Disinfectant Cleaner Wipe Canister

PDI
PDIQ55172
Purple
PDI Super Sani-Cloth Surface Disinfectant Cleaner Wipe Canister Cover
Professional Disposables Surface Disinfectant Super Sani-Cloth Wipes, 160Count

Keep your healthcare environment safe and clean with PDI Disinfectant Wipes. These wipes are effective against 30 microorganisms including MRSA, VRE, HIV and HBV, and are compatible with a broad range of surfaces and equipment. With 160 wipes per canister and 55% isopropyl alcohol, these wipes are perfect for quick and easy cleaning. The wipes are 6 X 675 inch in size, making them easy to handle. Use PDI Disinfectant Wipes to ensure the safety of your staff and patients while providing a convenient and efficient cleaning solution.

What We Like
Effective against 30 microorganisms
Compatible with a broad range of surfaces and equipment
160 wipes per canister
#TOP 5 Best Natural

Seventh Generation Disinfecting Multi-Surface Wipes

SG-068
Multi
Seventh Generation Disinfecting Multi-Surface Wipes Cover
Seventh Generation Disinfecting Multi-Surface Wipes, Lemongrass Citrus, 70 Count, Pack of 3 (Packaging May Vary)

These disinfectant wipes from Seventh Generation are perfect for daily cleaning tasks and tough jobs. They clean and disinfect in one easy step, killing 99.99% of bacteria and viruses. The wipes are made with a botanical disinfectant containing Thymol and have a Lemongrass Citrus Scent. They leave no residue and do not require rinsing, even on food contact surfaces and children's toys.

What We Like
Convenient for daily touch-ups and tough cleaning jobs
Kills 99.99% of bacteria and viruses
No rinse required, even on food contact surfaces and children's toys
Buying Guide Image

Household Disinfectant Wipes to Remove Germs

Household disinfectant wipes consist of a germ-killing solution, making them capable of killing viruses and bacteria on surfaces like countertops, doorknobs, smartphones, and other hard surfaces. The demand for disinfectant wipes has increased significantly due to their countless benefits. Due to such high demand, numerous companies have launched their wipes, making it arduous to choose the right and reliable one. Read ahead to know all the essential things that you must know before purchasing household disinfectant wipes.

Advantages of Household Disinfectant Wipes

Works Effectively with Active Ingredients

According to the US Institute of Antimicrobial Resistance and Infection Control, wipes reduce the highest ATP from the surfaces. This theory is valid for wipes that consist of the correct ratio of active ingredients as they will lose fewer substances resulting in wipes working more effectively and remove germs.

Convenient

You are no longer needed to carry a bowl of water with disinfectant fluid along with a sponge to clean your house when you have an option of using disinfectant wipes. The disinfectant wipes will clean all the hard surfaces at your place quickly without any hassle.

Safe to Use

Experts conduct proper research and tests before adding the active ingredients to the wipes, reducing the possibility of harmful effects by the wipes. Unlike a disinfectant spray, the particles can not be released and inhaled by the users and surrounding people. Furthermore, disinfectant wipes are designed to be used once, thus reducing the risk of cross-contamination or overuse of dirty rags.

Reduces Contact Moments

Disinfectant wipes usually come along with a dispenser which does not only enhances the overall appearance but with disinfectant wipes placed in the dispenser, the contact moment is also reduced.

How to Properly Use Household Disinfectant Wipes?

  • The first step you must take is to look at the product's packaging to find the EPA registration number to confirm that the product is EPA approved.
  • Next, thoroughly read all the instructions and warnings as it usually contains beneficial information. At times it asks you to wear gloves before using them, and at some places, it tells you what to do if a drop of cleaning solutions enters your eyes.
  • Then, remove all the dirt and debris from the surface before using the wipes to ensure that the wipes disinfect your surface correctly. Wipes can not get in touch with germs if there is a layer of dirt and debris.
  • Now clean the surface using the disinfectant wipes. Make sure that the entire surface is wet as the solution needs time to kill all the germs. The amount of time that you must leave it on the surface without cleaning or washing it, also known as Contact Time, would be mentioned on the packaging.
  • After that, remove your gloves and wash your hands properly with soap and water.
  • Rinse the surface once the contact time is over.

Frequently Asked Questions

Q) What is the difference between disinfectant wipes and antibacterial wipes?

Disinfectant wipes are for hard surfaces like kitchen countertops, side tables, doorknobs, etc. However, antibacterial wipes are usually used for cleaning hands. Antibacterial wipes will kill bacteria, not viruses; on the other hand, disinfectant wipes will kill both.

Q) Will my disinfectant wipe work after it has dried out?

No, it won't work once the wipe has died out. Disinfectant wipes often have a high alcohol content to kill bacteria and viruses. But alcohol is also the reason why liquid evaporates quickly, making it ineffective. Disinfectant wipes will only work while wet.

Frequently Asked Questions (FAQs)

1. What do you use disinfecting wipes for?

Disinfecting wipes are used to clean and disinfect surfaces, killing 99.9% of germs including viruses and bacteria. They are effective against various pathogens such as cold and flu germs, MRSA, staph, E. coli, strep, salmonella, and the organism that causes whooping cough.

2. Is it better to spray or wipe disinfectant?

Both disinfectant spray and wipes are effective when used correctly, but wipes are generally more user-friendly. They provide an easy and convenient way to clean and disinfect surfaces. Wipes also have a wider range of usage compared to spray disinfectants, as they eliminate the need for potentially harmful liquids.

3. Why you should stop using Clorox wipes?

There are concerns about the chemicals in Clorox wipes being absorbed dermally or orally, as well as the potential risk of inhalation. These chemicals can also attach to dust and become airborne. It is important to consider these factors and choose alternative disinfecting options if you have sensitivities or concerns.

4. Do you have to rinse after using disinfectant wipes?

If the surface is to be used for food preparation or eating, it is recommended to rinse the area with fresh water and dry it with a clean towel after the disinfectant has dried. This helps remove any residual chemicals and ensure the surface is safe for food contact.

5. Can you use disinfecting wipes to clean yourself?

Disinfecting wipes, including kitchen disinfecting wipes, are not safe for direct skin contact. They are formulated with harsh ingredients that can cause skin irritation and contact dermatitis. It is important to use these wipes only for their intended purpose of cleaning and disinfecting surfaces.

Editor's Notes

During our disinfectant wipe research, we found 26 disinfectant wipe products and shortlisted 5 quality products. We collected and analyzed 1,394,499 customer reviews through our big data system to write the disinfectant wipes list. We found that most customers choose disinfectant wipes with an average price of $11.97.

The disinfectant wipes are available for purchase. We have researched hundreds of brands and picked the top brands of disinfectant wipes, including CLOROX, Lysol, PDI, Seventh Generation. The seller of top 1 product has received honest feedback from 385 consumers with an average rating of 4.7.

Written by
Bonnie Salem Avatar

Bonnie Salem is a stay-at-home mother with two-year-old twins and has spent almost half of her life surrounded by baby products. As a mother and a professional copywriter, she has an insightful and unique eye for researching products suitable for infants. Bonnie Salem is an expert in health and nutrition who lives with her family in New Jersey. She has over 15 years of working experience in an institute of medicine after graduating from the University of Toronto. She is highly interested in personal health and wellness.