Best Commercial Drain Openers of 2025

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Commercial drain openers are powerful and effective solutions designed to unclog and clear stubborn blockages in commercial plumbing systems. These products are formulated with strong chemicals that dissolve hair, grease, and other organic materials that cause blockages in drain pipes. Commercial drain openers come in different types, including acidic, alkaline, and enzymatic formulas, and they work quickly to break down and dissolve blockages. These products are ideal for use in restaurants, hotels, hospitals, and other commercial settings where clogged drains can cause serious disruptions to business operations.
At a Glance: Our Top Picks
Top 10 Commercial Drain Openers
Green Gobbler Industrial Strength Drain Clog Remover
Green Gobbler Industrial Strength Drain Clog Remover is a powerful and easy-to-use drain cleaner gel that liquefies the toughest clogs, including hair, grease, soap scum, flushable wipes, and more. Its 3X thicker formula clings to clogs and removes hard water and mineral deposits. The odorless formula is safe for pipes, toilets, sinks, tubs, drains, and septic tanks, making it an excellent alternative to traditional bleach-based drain openers. Plus, it comes with a money-back guarantee.
Zep Advanced Tub and Shower Drain Opener Gel
Zep Advanced Tub and Shower Drain Opener Gel is a targeted solution for clearing clogs in tub and shower drains. Its thick gel formula can quickly dissolve hair, soap scum, and conditioner, cutting through standing water and directly to the clog in seconds. This product is safe for all pipes and septic systems, and is uniquely designed for tub and shower drains.
Instant Power Enzyme Drain Cleaner
Instant Power Drain Cleaner effectively tackles clogs in your kitchen and restroom drains. It uses natural enzymes to break down grease, food particles, and other debris, helping you maintain a clear drainage system. By addressing potential blockages early, you can avoid costly emergencies that disrupt your daily routine. Additionally, this product eliminates unpleasant odors caused by build-up, ensuring a fresh environment. Safe for your pipes and eco-friendly, it offers a reliable solution without harsh chemicals, making it a smart choice for both home and business use.
PEQUA P-10232 Heavy Duty Drain Opener
The PEQUA Drain Opener is a powerful solution designed to effectively unclog your drains. Its professional-grade formula helps you tackle tough blockages, such as grease and hair, without damaging your pipes. You can trust this product to safely and efficiently clear clogs, making it suitable for both home and commercial use. Plus, it’s odorless and easy to use, ensuring a comfortable experience even for those sensitive to strong chemicals. Just apply, wait, and rinse to restore your drains to full functionality.
ComStar Pure Lye Drain Opener
ComStar Pure Lye is an eco-friendly, industrial-strength, 99% pure sodium hydroxide bead formula that clears out drains, grease traps, and septic systems, while also being safe on fixtures. Its unique bead shape quickly attacks the cause of the blockage for a fast break-up, and it's a favorite product for soap makers due to its small, static-free beads that dissolve quickly. It's non-acid, biodegradable formula is safe on fine fixtures, chrome trim, and metal or plastic pipes, and enhances growth of active bacteria when applied regularly.
Zep Drain Defense Pipe Build-Up Remover - ZLDC648
Zep Drain Defense is a professional strength liquid pipe build-up remover that breaks down drain-clogging elements using an enzyme-based formula. It is safe for PVC and most other septic systems, making it suitable for use in sinks, garbage disposals, tub/shower drains, RVs, and grease traps. By using it monthly, you can prevent clogs, slow drains, and restore flow. The formula breaks down into CO2, minerals, and water, which means it is environmentally friendly. Enzymes remove years of build-up, providing 21 months of drain protection. With Zep Drain Defense, you can keep your plumbing system running smoothly and avoid costly repairs.
Bioda Drain Cleaner and Odor Eliminator
Bioda Drain Cleaner is a versatile and effective solution for keeping your drains clear and odor-free. With its preventative probiotic and enzyme formula, it helps to prevent clogs from forming in your plumbing system. This unique blend of enzymes and probiotics breaks down the buildups caused by grease, soap scum, and food particles, ensuring that your drains keep flowing smoothly. Not only is it highly effective, but it is also safe for your pipes and septic system, thanks to its use of beneficial bacteria instead of harsh chemicals. Additionally, Bioda Drain Cleaner eliminates odors at their source by breaking down the grease, fats, and other organic matter that cause unpleasant smells. Whether you need to unclog your kitchen sink, bathroom sink, garbage disposal, or even your RV or boat holding tanks, Bioda Drain Cleaner is the ideal solution.
Liquid-Plumr Clog Destroyer Gel
Liquid-Plumr Clog Gel offers a powerful solution for stubborn drain clogs. Its 3-in-1 formula not only breaks down tough blockages like hair and grease, but also helps prevent future clogs, ensuring your drains remain clear. This gel is safe for all types of pipes, including PVC and copper, which means you can use it without worrying about damage. Additionally, it effectively eliminates unpleasant odors from your drains, making your home feel fresher. Using this product monthly can help maintain clear pipes and extend the life of your plumbing.
Zep 10 Minute Drain Opener Gel
Zep Drain Opener Gel is designed to tackle stubborn clogs quickly, making it ideal for busy households. Its commercial-strength formula effectively penetrates standing water to dissolve hair and grease, ensuring your drains flow freely. You’ll appreciate how it protects your pipes from corrosion, extending their lifespan. Whether you’re dealing with bathroom sinks, tubs, or shower drains, this gel is safe for all types of plumbing, including metal, plastic, and brass, as well as septic systems. Enjoy hassle-free drain maintenance with this powerful solution at your side.
Best Eco Friendly Drain Line Cleaner for Residential or Commercial Drains
This eco-friendly drain line cleaner is effective against various types of clogs such as grease, hair, rust, and more. It can be used for bathroom sinks, toilets, kitchen sinks, floor drains, urinals, and other types of drains. Compared to toxic liquid drain chemicals, this cleaner is a safer alternative. The product comes with a guarantee, and the manufacturer will reimburse dissatisfied customers in full.
Frequently Asked Questions (FAQs)
1. How do you unclog a commercial drain?
For basic drain maintenance, you can use soapy water and a drain snake or auger to break up clogs. However, some clogs may require professional help. It is also recommended to have a professional inspection of commercial floor drain pipes at least once a year to prevent clogs.
2. What do plumbers use to open drains?
Plumbers often use hydrochloric acid, also known as muriatic acid, to dissolve clogs in drains. This strong acid breaks down organic materials like hair, grease, and soap scum that can accumulate in pipes and cause blockages.
3. What will dissolve hair in a drain?
To dissolve hair in a drain, you can use baking soda. Start by pouring a cup of baking soda down the drain, followed by a cup of vinegar (white vinegar). Allow the mixture to sit for several minutes. This safe and easy method can help dissolve hair and clear the drain.
4. How do you unclog the toughest drain?
There are a few methods you can try for tough clogs. One method is to pour equal parts of baking soda and salt down the drain, let it sit for 20-30 minutes, and then flush it with hot water. Another method is to mix equal parts of salt and vinegar in a bowl, add a half part of lemon juice, and pour the mixture down the drain.
5. How do you clear a severely clogged drain?
To clear a severely clogged drain, you can try the following steps: remove standing water, remove visible blockages and check the garbage disposal, try pouring boiling water and salt or vinegar and baking soda down the drain, use a plunger, clean the P-trap and use a drain snake.
6. What do professionals use to unclog drains?
Professionals often use a cable and drum machine to unclog drains. This equipment consists of a long steel wire cable with a cutting head on one end. The cable is inserted into the drain to scrape away stubborn clogs until the flow is restored.
During our commercial drain opener research, we found 24 commercial drain opener products and shortlisted 10 quality products. We collected and analyzed 77,713 customer reviews through our big data system to write the commercial drain openers list. We found that most customers choose commercial drain openers with an average price of $20.51.
The commercial drain openers are available for purchase. We have researched hundreds of brands and picked the top brands of commercial drain openers, including Green Gobbler, Zep, Instant Power, PEQUA INDUSTRIES, Comstar. The seller of top 1 product has received honest feedback from 4,036 consumers with an average rating of 4.9.

Brian Howie is a content writer and senior industrial designer. After graduation from Westminster College, he has been engaged in product design and manufacturing for 18 years. Brian Howie has always found great pleasure in designing industrial products and sharing his ideas and experience online.