Best Anesthetic & Antiseptic Oral Rinses of 2025

Plax Advanced PreBrushing Dental Rinse is a soft mint-flavored oral rinse that helps loosen and remove plaque when used before brushing. This rinse is clinically proven to remove more plaque than brushing alone. It has a pleasant taste and is easy to use. It is recommended to read all label information before use. This product falls under the category of Anesthetic & Antiseptic Oral Rinses.

Canker-X Mouthwash is a fast-acting and effective oral rinse that provides quick pain relief and promotes healing for various mouth sores. This clinically tested benzocaine-free and alcohol-free mouthwash is ideal for treating canker sores, cheek bites, mouth burns, gum sores, abrasions from braces and dentures, and other types of mouth sores. It works by forming a micro-thin, protective coating over the sores, soothing them, and blocking irritants like food and drink. With the goodness of Aloe Vera, Sodium Hyaluronate, and Polyvinylpyrrolidone (PVP), it provides up to 6 hours of pain relief. The easy-to-use measurement cap ensures the right amount is used, and the pleasant taste makes it suitable for multiple mouth sores. Safe for both children (6+ years) and adults, Canker-X Mouthwash is a reliable solution for fast pain relief and healing.

TheraBreath Healthy Gums Oral Rinse is formulated to support gum health, combat bad breath, and prevent oral problems such as gingivitis, plaque, and tartar buildup. It is dentist-formulated and contains CPC. The premium oral care line of TheraBreath includes toothpaste, mouthwash, breath sprays, tonsil stone kits, and more. The professional-grade products can help address halitosis, cavity prevention, and gum disease. The brand has been trusted since 1994.

S.T.37 Antiseptic Liquid by NUMARK LABORATORIES INC is a general antiseptic solution for household use. It quickly kills common pathogenic bacteria, making it an effective solution for minor cuts, abrasions, and burns. Unlike other antiseptics, S.T.37 is gentle to use, causing little to no stinging or burning sensation. It even soothes irritated areas, providing comfort and relief. Another advantage is that it doesn't stain the skin or leave any unpleasant odor. With S.T.37 Antiseptic, you can easily keep your skin clean and protected without any hassle or discomfort.

MetaQil Mouthwash is the first-of-its-kind oral rinse scientifically designed to alleviate metallic, bitter, and unusual tastes caused by chemotherapy, radiation, COVID-19, medication, or GERD. Its unique formula contains eight natural ingredients, including vitamin E, menthol, peppermint, and spearmint, which provide instant cooling relief without any burning sensation. Its natural sweeteners and alcohol-free, gluten-free, and sugar-free formulation make it a convenient and safe choice for daily use. Simply swish 1 tsp (approx. 5 mL) of refreshing oral rinse for 30 seconds in the mouth, and then spit out for instant relief. Packaged in an 8 oz bottle, it is perfect for on-the-go use as a breath freshener and mouth moisturizer.

Orajel Alcohol-Free Antiseptic Rinse is an anesthetic and antiseptic oral rinse that kills bacteria and promotes the healing of sores inside the mouth, all while featuring a refreshing mint flavor. Additionally, it is alcohol-free, making it a gentler option for those with sensitive mouths.

Supersmile Oral Rinse Mouthwash is a sugar-free, mint-flavored mouthwash that provides long-lasting germicidal and antibacterial protection. It contains sodium bicarbonate for fresh breath, cetyl pyridinium chloride for antibacterial protection, and tetra potassium pyrophosphate to inhibit plaque formation. It falls under the category of anesthetic and antiseptic oral rinses.

Kanka Professional Strength Mouth Pain Relief is a maximum strength formula that provides fast and effective relief from mouth pain. It forms a protective coating to shield against further irritation, and comes with a convenient control tip for better application. The ultra soft brush tip gently gets between teeth and gums, while the unique applicator makes it easy to apply in hard-to-reach areas. Combining two analgesics for dual relief, this anesthetic and antiseptic oral rinse is perfect for those seeking strong relief with a soft touch.

TheraSol Concentrate is a versatile antiseptic oral rinse that can be used as a mouthwash, an irrigation solution for shallow pockets, and for deep pockets where normal irrigation can't reach. It helps to maintain good oral hygiene by rinsing around the gumline and irrigating hard-to-reach areas.